In vivo oxidative metabolism of a major peroxidation-derived DNA adduct, M1dG. (Q34597942)

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19 January 2020

title

In vivo oxidative metabolism of a major peroxidation-derived DNA adduct, M1dG (English)

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19 January 2020

8

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Brenda C Crews

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19 January 2020

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Lawrence J Marnett

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19 January 2020

author name string

Michael B Otteneder

1

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19 January 2020

Charles G Knutson

2

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19 January 2020

J Scott Daniels

3

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19 January 2020

Muhammed Hashim

4

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19 January 2020

Rory P Remmel

6

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19 January 2020

Hao Wang

7

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language of work or name

English

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publication date

13 April 2006

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Proceedings of the National Academy of Sciences of the United States of America

19 January 2020

published in

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volume

103

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19 January 2020

issue

17

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page(s)

6665-6669

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Pyrimido[1,2-a]-purin-10(3H)-one, M1G, is less prone to artifact than base oxidation

19 January 2020

cites work

1 reference

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Measurement of the malondialdehyde-2'-deoxyguanosine adduct in human urine by immuno-extraction and liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry

7 July 2018

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Induction of frameshift and base pair substitution mutations by the major DNA adduct of the endogenous carcinogen malondialdehyde

7 July 2018

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Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein

7 July 2018

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Pyrimido[1,2-alpha]purin-10(3H)-one: a reactive electrophile in the genome.

7 July 2018

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Oxyradicals and DNA damage

7 July 2018

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Synthesis of oligonucleotides containing the alkali-labile pyrimidopurinone adduct, M(1)G

7 July 2018

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Indirect mutagenesis by oxidative DNA damage: formation of the pyrimidopurinone adduct of deoxyguanosine by base propenal

7 July 2018

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7 July 2018

Oxidative Decay of DNA

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Mutagenicity in Escherichia coli of the major DNA adduct derived from the endogenous mutagen malondialdehyde

7 July 2018

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Metabolic studies of allopurinol, an inhibitor of xanthine oxidase

7 July 2018

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Excretion of benzo[a]pyrene-Gua adduct in the urine of benzo[a]pyrene-treated rats

7 July 2018

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Excretion of the mercapturic acid S-[2-(N7-guanyl)ethyl]-N-acetylcysteine in urine following administration of ethylene dibromide to rats

7 July 2018

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Relevance of urinary DNA adducts as markers of carcinogen exposure

7 July 2018

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Quantification of multiple DNA adducts formed through oxidative stress using liquid chromatography and electrospray tandem mass spectrometry

7 July 2018

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Chemical and biological evidence for base propenals as the major source of the endogenous M1dG adduct in cellular DNA.

21 January 2018

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In vitro bypass of malondialdehyde-deoxyguanosine adducts: differential base selection during extension by the Klenow fragment of DNA polymerase I is the critical determinant of replication outcome

21 January 2018

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Repair of propanodeoxyguanosine by nucleotide excision repair in vivo and in vitro

21 January 2018

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Development of a method for determination of the malondialdehyde-deoxyguanosine adduct in urine using liquid chromatography-tandem mass spectrometry

21 January 2018

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Potent inhibition of human liver aldehyde oxidase by raloxifene

21 January 2018

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Reaction of malondialdehyde-DNA adducts with hydrazines-development of a facile assay for quantification of malondialdehyde equivalents in DNA.

21 January 2018

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Kinetic and thermodynamic analysis of the hydrolytic ring-opening of the malondialdehyde-deoxyguanosine adduct, 3-(2'-deoxy-beta-D-erythro-pentofuranosyl)- pyrimido[1,2-alpha]purin-10(3H)-one

21 January 2018

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Oxidative stress and lipid peroxidation-derived DNA-lesions in inflammation driven carcinogenesis.

21 January 2018

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Characterization of 2'-deoxycytidine adducts derived from 4-oxo-2-nonenal, a novel lipid peroxidation product

21 January 2018

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4,5-Epoxy-2(E)-decenal-induced formation of 1,N(6)-etheno-2'-deoxyadenosine and 1,N(2)-etheno-2'-deoxyguanosine adducts.

21 January 2018

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Formation of cyclic 1,N2--adducts by reaction of deoxyguanosine with alpha-acetoxy-N-nitrosopyrrolidine, 4-(carbethoxynitrosamino)butanal, or crotonaldehyde.

21 January 2018

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Stereocontrolled syntheses of all four stereoisomeric 1,N2-deoxyguanosine adducts of the lipid peroxidation product trans-4-hydroxynonenal

26 October 2018

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12 December 2020

Excretion of an aflatoxin-guanine adduct in the urine of aflatoxin B1-treated rats

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12 December 2020

Isolation of urinary 3-methyladenine using immunoaffinity columns prior to determination by low-resolution gas chromatography-mass spectrometry

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Human liver oxidative metabolism of O6-benzylguanine

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Analysis of the malondialdehyde-2'-deoxyguanosine adduct pyrimidopurinone in human leukocyte DNA by gas chromatography/electron capture/negative chemical ionization/mass spectrometry

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0602017103

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19 January 2020

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19 January 2020

PubMed publication ID

16614064

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