TSG-6 as a biomarker to predict efficacy of human mesenchymal stem/progenitor cells (hMSCs) in modulating sterile inflammation in vivo. (Q34601443)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25385603%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

TSG-6 as a biomarker to predict efficacy of human mesenchymal stem/progenitor cells (hMSCs) in modulating sterile inflammation in vivo (English)

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22 February 2020

0 references

0 references

6

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22 February 2020

8

Darwin J Prockop

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22 February 2020

author name string

Ryang Hwa Lee

1

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22 February 2020

Ji Min Yu

2

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22 February 2020

Andrea M Foskett

3

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22 February 2020

Grant Peltier

4

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22 February 2020

John C Reneau

5

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22 February 2020

Joo Youn Oh

7

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22 February 2020

language of work or name

English

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publication date

10 November 2014

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22 February 2020

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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22 February 2020

volume

111

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22 February 2020

issue

47

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22 February 2020

page(s)

16766-16771

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Phase-directed therapy: TSG-6 targeted to early inflammation improves bleomycin-injured lungs

22 February 2020

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TSG-6 produced by hMSCs delays the onset of autoimmune diabetes by suppressing Th1 development and enhancing tolerogenicity

7 July 2018

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Intravenous mesenchymal stem cells prevented rejection of allogeneic corneal transplants by aborting the early inflammatory response

7 July 2018

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7 July 2018

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7 July 2018

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Medical therapies with adult stem/progenitor cells (MSCs): a backward journey from dramatic results in vivo to the cellular and molecular explanations

7 July 2018

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Mesenchymal stem/stromal cells (MSCs): role as guardians of inflammation

7 July 2018

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Therapeutic factors secreted by mesenchymal stromal cells and tissue repair

7 July 2018

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Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-κB signaling in resident macrophages.

7 July 2018

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Sterile inflammation: sensing and reacting to damage

7 July 2018

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Anti-inflammatory protein TSG-6 reduces inflammatory damage to the cornea following chemical and mechanical injury.

7 July 2018

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Sox11 is expressed in early progenitor human multipotent stromal cells and decreases with extensive expansion of the cells

7 July 2018

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Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6

7 July 2018

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The estrogen 17beta-estradiol and phytoestrogen genistein mediate differential effects on osteoblastic NF-kappaB activity.

7 July 2018

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Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production

7 July 2018

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Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury

7 July 2018

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TSG-6 protein binding to glycosaminoglycans: formation of stable complexes with hyaluronan and binding to chondroitin sulfates.

7 July 2018

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TSG-6: a multifunctional protein associated with inflammation

7 July 2018

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Identification of a subpopulation of rapidly self-renewing and multipotential adult stem cells in colonies of human marrow stromal cells

7 July 2018

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Donor variation in the growth properties and osteogenic potential of human marrow stromal cells

7 July 2018

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TSG-6: An IL-1 /TNF-inducible protein with anti-inflammatory activity

7 July 2018

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Activation of the TSG-6 gene by NF-IL6 requires two adjacent NF-IL6 binding sites

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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21 January 2018

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Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation

21 January 2018

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21 January 2018

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21 January 2018

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12 December 2020

Action at a distance: systemically administered adult stem/progenitor cells (MSCs) reduce inflammatory damage to the cornea without engraftment and primarily by secretion of TNF-α stimulated gene/protein 6

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12 December 2020

Stem cell therapy market

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1416121111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25385603%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

0 references

1 reference

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22 February 2020

PubMed publication ID

25385603

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25385603%20AND%20SRC:MED&resulttype=core&format=json