ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis (Q34602870)

3 August 2017

title

ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis (English)

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3 August 2017

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11

Wolfgang W Schamel

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19

Stephan Ehl

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3

Anne Rensing-Ehl

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3 August 2017

Andrea Maul-Pavicic

1

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3 August 2017

Samuel C C Chiang

2

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Birthe Jessen

4

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Cyril Fauriat

5

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Stephanie M Wood

6

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Sebastian Sjöqvist

7

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Markus Hufnagel

8

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Ilka Schulze

9

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3 August 2017

Thilo Bass

10

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Sebastian Fuchs

12

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Hanspeter Pircher

13

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Christie-Ann McCarl

14

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Katsuhiko Mikoshiba

15

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Klaus Schwarz

16

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Stefan Feske

17

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Yenan T Bryceson

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3 August 2017

language of work or name

English

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publication date

7 February 2011

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3 August 2017

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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3 August 2017

volume

108

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3 August 2017

issue

8

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3 August 2017

page(s)

3324-3329

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Molecular mechanisms of biogenesis and exocytosis of cytotoxic granules

3 August 2017

cites work

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7 July 2018

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Molecular basis of calcium signaling in lymphocytes: STIM and ORAI

7 July 2018

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7 July 2018

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Two novel 2-aminoethyl diphenylborinate (2-APB) analogues differentially activate and inhibit store-operated Ca(2+) entry via STIM proteins.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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R93W mutation in Orai1 causes impaired calcium influx in platelets

7 July 2018

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Hair loss and defective T- and B-cell function in mice lacking ORAI1

7 July 2018

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Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release-activated calcium channels

7 July 2018

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Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients

7 July 2018

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7 July 2018

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7 July 2018

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Genetic defects affecting lymphocyte cytotoxicity

7 July 2018

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Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis

7 July 2018

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7 July 2018

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7 July 2018

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Analysis of natural killer-cell function in familial hemophagocytic lymphohistiocytosis (FHL): defective CD107a surface expression heralds Munc13-4 defect and discriminates between genetic subtypes of the disease

7 July 2018

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CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry

7 July 2018

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A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

7 July 2018

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Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells.

7 July 2018

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7 July 2018

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STIM1, an essential and conserved component of store-operated Ca2+ channel function

7 July 2018

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7 July 2018

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7 July 2018

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Role of calcium influx in cytotoxic T lymphocyte lytic granule exocytosis during target cell killing

7 July 2018

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CD18 activation epitopes induced by leukocyte activation

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Antigen receptor-regulated exocytosis in cytotoxic T lymphocytes

7 July 2018

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Transmembrane signaling during natural killer cell-mediated cytotoxicity. Regulation by protein kinase C activation

7 July 2018

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Linker for activation of T cells, zeta-associated protein-70, and Src homology 2 domain-containing leukocyte protein-76 are required for TCR-induced microtubule-organizing center polarization

7 July 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1013285108

Localized diacylglycerol drives the polarization of the microtubule-organizing center in T cells

21 January 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1013285108

Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3).

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.1013285108

Dynamic polarization of the microtubule cytoskeleton during CTL-mediated killing.

21 January 2018

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The duration of nuclear residence of NFAT determines the pattern of cytokine expression in human SCID T cells

26 October 2018

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12 December 2020

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

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12 December 2020

Requirements for triggering of lysis by cytolytic T lymphocyte clones

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12 December 2020

Severe combined immunodeficiency due to defective binding of the nuclear factor of activated T cells in T lymphocytes of two male siblings

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12 December 2020

Full Activation of the T Cell Receptor Requires Both Clustering and Conformational Changes at CD3

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1013285108

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3 August 2017

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3 August 2017

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