Triacylglycerol accumulation activates the mitochondrial apoptosis pathway in macrophages (Q34606342)

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19 January 2020

title

Triacylglycerol accumulation activates the mitochondrial apoptosis pathway in macrophages (English)

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19 January 2020

5

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19 January 2020

Julia Ring

6

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19 January 2020

Heimo Wolinski

9

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19 January 2020

Sepp D Kohlwein

10

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19 January 2020

Rudolf Zechner

11

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19 January 2020

Wolfgang Graier

14

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19 January 2020

Roland Malli

15

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19 January 2020

Dagmar Kratky

17

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19 January 2020

author name string

Elma Aflaki

1

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19 January 2020

Branislav Radovic

2

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19 January 2020

Prakash G Chandak

3

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19 January 2020

Dagmar Kolb

4

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19 January 2020

Ismene Fertschai

7

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19 January 2020

Andreas Uellen

8

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19 January 2020

Sanja Levak-Frank

12

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19 January 2020

Wolfgang Sattler

13

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19 January 2020

Frank Madeo

16

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19 January 2020

language of work or name

English

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publication date

1 January 2011

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19 January 2020

number of pages

11

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Journal of Biological Chemistry

inferred from page(s)

published in

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19 January 2020

volume

286

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19 January 2020

issue

9

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19 January 2020

page(s)

7418-7428

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Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice

19 January 2020

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Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase

7 July 2018

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7 July 2018

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Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways.

7 July 2018

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Triglyceride alters lysosomal cholesterol ester metabolism in cholesteryl ester-laden macrophage foam cells

7 July 2018

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Lipid droplets at a glance

7 July 2018

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7 July 2018

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An increase in intracellular Ca2+ is required for the activation of mitochondrial calpain to release AIF during cell death

7 July 2018

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Mertk receptor mutation reduces efferocytosis efficiency and promotes apoptotic cell accumulation and plaque necrosis in atherosclerotic lesions of apoe-/- mice

7 July 2018

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The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy

7 July 2018

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Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase

7 July 2018

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Cholesterol-induced macrophage apoptosis requires ER stress pathways and engagement of the type A scavenger receptor

7 July 2018

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Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase

7 July 2018

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Reduced macrophage apoptosis is associated with accelerated atherosclerosis in low-density lipoprotein receptor-null mice

7 July 2018

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Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities

7 July 2018

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Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis.

7 July 2018

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Consequences of cellular cholesterol accumulation: basic concepts and physiological implications

7 July 2018

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Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

7 July 2018

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CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation

7 July 2018

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Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis

7 July 2018

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7 July 2018

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Free cholesterol loading of macrophages induces apoptosis involving the fas pathway.

7 July 2018

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Apoptosis driven by IP(3)-linked mitochondrial calcium signals

7 July 2018

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Mitochondrial depolarization accompanies cytochrome c release during apoptosis in PC6 cells

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Free cholesterol loading of macrophages is associated with widespread mitochondrial dysfunction and activation of the mitochondrial apoptosis pathway

21 January 2018

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The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages

21 January 2018

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Triglyceride deposit cardiomyovasculopathy

21 January 2018

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Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis

21 January 2018

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Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells

21 January 2018

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Hydrolysis and excretion of cytoplasmic cholesteryl esters by macrophages: stimulation by high density lipoprotein and other agents

21 January 2018

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12 December 2020

Novel duplication mutation in the patatin domain of adipose triglyceride lipase (PNPLA2) in neutral lipid storage disease with severe myopathy

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12 December 2020

The lack of the C-terminal domain of adipose triglyceride lipase causes neutral lipid storage disease through impaired interactions with lipid droplets

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12 December 2020

Cell toxicity induced by inhibition of acyl coenzyme A:cholesterol acyltransferase and accumulation of unesterified cholesterol

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12 December 2020

Effects of intracellular free cholesterol accumulation on macrophage viability: a model for foam cell death

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12 December 2020

Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange

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12 December 2020

Biphasic pattern of cell turnover characterizes the progression from fatty streaks to ruptured human atherosclerotic plaques

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12 December 2020

Identifiers

DOI

10.1074/JBC.M110.175703

1 reference

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19 January 2020

1 reference

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19 January 2020

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