Reduced syncytin-1 expression levels in placental syndromes correlates with epigenetic hypermethylation of the ERVW-1 promoter region (Q34606561)

3 August 2017

title

Reduced syncytin-1 expression levels in placental syndromes correlates with epigenetic hypermethylation of the ERVW-1 promoter region (English)

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3 August 2017

1 reference

8

Fabian B Fahlbusch

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3 August 2017

3

Arif B Ekici

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3 August 2017

9

Matthias W Beckmann

1 reference

3 August 2017

Matthias Ruebner

1

1 reference

3 August 2017

Pamela L Strissel

2

1 reference

3 August 2017

Elisabeth Stiegler

4

1 reference

3 August 2017

Ulf Dammer

5

1 reference

3 August 2017

Tamme W Goecke

6

1 reference

3 August 2017

Florian Faschingbauer

7

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3 August 2017

Reiner Strick

10

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3 August 2017

language of work or name

English

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publication date

14 February 2013

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3 August 2017

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3 August 2017

volume

8

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3 August 2017

issue

2

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3 August 2017

page(s)

e56145

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Creative Commons Attribution 4.0 International

3 August 2017

copyright license

start time

14 February 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Syncytin-1 and glial cells missing a: hypoxia-induced deregulated gene expression along with disordered cell fusion in primary term human trophoblasts

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Effect of cryopreservation on human cytotrophoblast cells in culture: hCG and PALP production.

7 July 2018

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Apoptosis and its role in the trophoblast

7 July 2018

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CpG methylation suppresses transcriptional activity of human syncytin-1 in non-placental tissues

7 July 2018

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7 July 2018

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DNA binding selectivity of MeCP2 due to a requirement for A/T sequences adjacent to methyl-CpG.

7 July 2018

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Human endogenous retroviruses: from infectious elements to human genes

7 July 2018

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Structural and sequence motifs of protein (histone) methylation enzymes

7 July 2018

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Functional characterization of two newly identified Human Endogenous Retrovirus coding envelope genes

7 July 2018

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Diagnosis, prevention, and management of eclampsia

7 July 2018

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CpG methylation directly regulates transcriptional activity of the human endogenous retrovirus family HERV-K(HML-2)

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573012

A retroviral promoter and a cellular enhancer define a bipartite element which controls env ERVWE1 placental expression.

7 July 2018

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Identification of endogenous retroviral reading frames in the human genome

7 July 2018

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Lsh, an epigenetic guardian of repetitive elements

7 July 2018

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The distribution and expression of HERV families in the human genome

7 July 2018

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Retroelements and the human genome: new perspectives on an old relation

7 July 2018

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MED1: a central molecule for maintenance of genome integrity and response to DNA damage

7 July 2018

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Isolation and Characterization of the Human Syncytin Gene Promoter1

7 July 2018

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Transcriptional effects of hypoxia on fusiogenic syncytin and its receptor ASCT2 in human cytotrophoblast BeWo cells and in ex vivo perfused placental cotyledons

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573012

Lsh, a modulator of CpG methylation, is crucial for normal histone methylation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573012

Hypoxia alters expression and function of syncytin and its receptor during trophoblast cell fusion of human placental BeWo cells: implications for impaired trophoblast syncytialisation in pre-eclampsia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573012

Direct Involvement of HERV-W Env Glycoprotein in Human Trophoblast Cell Fusion and Differentiation

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573012

Molecular epidemiology of preeclampsia

7 July 2018

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GCMa regulates the syncytin-mediated trophoblastic fusion

7 July 2018

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Mechanisms of syncytial fusion: a review

7 July 2018

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Molecular mechanisms of gene silencing mediated by DNA methylation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573012

DNA methylation patterns and epigenetic memory

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573012

Reprogramming of genome function through epigenetic inheritance

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573012

Epigenetic reprogramming in mammalian development

7 July 2018

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Initial sequencing and analysis of the human genome

7 July 2018

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An envelope glycoprotein of the human endogenous retrovirus HERV-W is expressed in the human placenta and fuses cells expressing the type D mammalian retrovirus receptor

7 July 2018

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Etiology and pathogenesis of preeclampsia: current concepts

7 July 2018

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

7 July 2018

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MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

7 July 2018

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The viruses in all of us: characteristics and biological significance of human endogenous retrovirus sequences

7 July 2018

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Hemolysis, elevated liver enzymes and low platelet count. The HELLP syndrome

7 July 2018

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7 July 2018

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7 July 2018

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Maternal mortality associated with hypertensive disorders of pregnancy in Africa, Asia, Latin America and the Caribbean

7 July 2018

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Fetal growth restriction: a workshop report.

7 July 2018

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Hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome: a review of diagnosis and management

21 January 2018

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Expression of syncytin in leukemia and lymphoma cells.

21 January 2018

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Syncytin immunoreactivity in colorectal cancer: potential prognostic impact

21 January 2018

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Proliferation and cell-cell fusion of endometrial carcinoma are induced by the human endogenous retroviral Syncytin-1 and regulated by TGF-beta.

21 January 2018

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Distinct epigenetic phenotypes in seminomatous and nonseminomatous testicular germ cell tumors

21 January 2018

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Purification, Characterization, andin vitroDifferentiation of Cytotrophoblasts from Human Term Placentae*

21 January 2018

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Methylation status of a single CpG locus 3 bases upstream of TATA-box of receptor activator of nuclear factor-kappaB ligand (RANKL) gene promoter modulates cell- and tissue-specific RANKL expression and osteoclastogenesis.

21 January 2018

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Expression of HERV-W Env glycoprotein (syncytin) in the extravillous trophoblast of first trimester human placenta.

21 January 2018

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Histone deacetylase inhibitor trichostatin A induces cell-cycle arrest/apoptosis and hepatocyte differentiation in human hepatoma cells

21 January 2018

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Placental alkaline phosphatase (PLAP) staining and human chorionic gonadotropin (hCG) production in cultures of fresh and cryopreserved cytotrophoblasts isolated by CD9/MHC class I/MHC class II immunoelimination

21 January 2018

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12 December 2020

Involvement of connexin 43 in human trophoblast cell fusion and differentiation

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12 December 2020

Impaired cytotrophoblast cell-cell fusion is associated with reduced Syncytin and increased apoptosis in patients with placental dysfunction

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12 December 2020

Prognostic role of syncytin expression in breast cancer

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Surface area of chorionic villi of placentas: an index of intrauterine growth restriction of fetuses

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On the structure of the human placenta with full-time and immature foetus, living or dead

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Modulation of phosphatidylserine epitope expression by BeWo cells during forskolin treatment

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Impaired cell fusion and differentiation in placentae from patients with intrauterine growth restriction correlate with reduced levels of HERV envelope genes

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12 December 2020

Hypomethylation of functional retrotransposon-derived genes in the human placenta

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12 December 2020

10.1371/JOURNAL.PONE.0056145

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DOI

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3 August 2017

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3 August 2017

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