Cellular Werner phenotypes in mice expressing a putative dominant-negative human WRN gene (Q34608450)

3 August 2017

Cellular Werner phenotypes in mice expressing a putative dominant-negative human WRN gene (English)

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3 August 2017

L Wang

1

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3 August 2017

C E Ogburn

2

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3 August 2017

C B Ware

3

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3 August 2017

W C Ladiges

4

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3 August 2017

H Youssoufian

5

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3 August 2017

G M Martin

6

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3 August 2017

J Oshima

7

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3 August 2017

language of work or name

English

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publication date

1 January 2000

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3 August 2017

6

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inferred from page(s)

published in

Genetics

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3 August 2017

154

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3 August 2017

1

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3 August 2017

357-362

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WRN mutations in Werner syndrome

3 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1460888

Cloning of two new human helicase genes of the RecQ family: biological significance of multiple species in higher eukaryotes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1460888

A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1460888

Werner helicase is localized to transcriptionally active nucleoli of cycling cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1460888

Structure and function of the human Werner syndrome gene promoter: evidence for transcriptional modulation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1460888

Nucleolar localization of the Werner syndrome protein in human cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1460888

An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1460888

The Werner syndrome protein is a DNA helicase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1460888

DNA helicase activity in Werner's syndrome gene product synthesized in a baculovirus system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1460888

Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1460888

Positional cloning of the Werner's syndrome gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1460888

Cloning and characterization of RECQL, a potential human homologue of the Escherichia coli DNA helicase RecQ

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1460888

The Bloom's syndrome gene product is homologous to RecQ helicases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1460888

Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1460888

Clonal selection, attenuation and differentiation in an in vitro model of hyperplasia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1460888

Colony size distributions as a measure of in vivo and in vitro aging

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1460888

Growth characteristics of Werner syndrome cells in vitro

7 July 2018

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12 December 2020

Cytogenetic aspects of Werner syndrome

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12 December 2020

Spontaneous and induced chromosomal instability in Werner syndrome

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12 December 2020

The expression of proliferation-dependent antigens during the lifespan of normal and progeroid human fibroblasts in culture

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12 December 2020

Somatic mutations are frequent and increase with age in human kidney epithelial cells

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12 December 2020

Down-regulation of the defective transcripts of the Werner's syndrome gene in the cells of patients

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12 December 2020

Impaired nuclear localization of defective DNA helicases in Werner's syndrome

1 reference

12 December 2020

Hierarchical deterioration of body systems in Werner's syndrome: implications for normal ageing

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12 December 2020

Identifiers

PMCID

1460888

1 reference

3 August 2017

1 reference