Mucosal and enterocyte IL-6 production during sepsis and endotoxemia--role of transcription factors and regulation by the stress response (Q34614244)

3 August 2017

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title

Mucosal and enterocyte IL-6 production during sepsis and endotoxemia--role of transcription factors and regulation by the stress response (English)

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3 August 2017

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Eric Hungness

2

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ORCID Public Data File 2021

author name string

Timothy Pritts

1

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3 August 2017

Quan Wang

3

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3 August 2017

Bruce Robb

4

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3 August 2017

Dan Hershko

5

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3 August 2017

Per-Olof Hasselgren

6

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3 August 2017

language of work or name

English

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publication date

1 April 2002

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The American Journal of Surgery

3 August 2017

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3 August 2017

183

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3 August 2017

4

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3 August 2017

372-383

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Mucosal production of complement C3 and serum amyloid A is differentially regulated in different parts of the gastrointestinal tract during endotoxemia in mice

3 August 2017

1 reference

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Effect of sepsis or cytokine administration on release of gut peptides

7 January 2021

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Intestinal production of interleukin-1 alpha during endotoxemia in the mouse.

7 January 2021

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Sepsis and endotoxemia stimulate intestinal interleukin-6 production

7 January 2021

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Gut-derived mesenteric lymph but not portal blood increases endothelial cell permeability and promotes lung injury after hemorrhagic shock.

7 January 2021

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Sepsis increases production of total secreted proteins, vasoactive intestinal peptide, and peptide YY in isolated rat enterocytes

7 January 2021

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Endotoxin stimulates interleukin-6 production in intestinal epithelial cells. A synergistic effect with prostaglandin E2.

7 January 2021

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Role of the gut in multiple organ failure: bacterial translocation and permeability changes

7 January 2021

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Increased intestinal permeability following blunt and penetrating trauma

7 January 2021

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Increased gut permeability after hemorrhage is associated with upregulation of local and systemic IL-6

7 January 2021

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Colonic Mucosal Interleukin-6 in Inflammatory Bowel Disease

7 January 2021

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Cytokine serum level during severe sepsis in human IL-6 as a marker of severity

7 January 2021

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The pathophysiologic roles of interleukin-6 in human disease

7 January 2021

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Treatment of endotoxemic mice with anti-interleukin-6 antibody paradoxically increases interleukin-6 levels and stimulates mucosal protein synthesis

7 January 2021

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Interleukins and IgA synthesis. Human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cells

7 January 2021

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Endotoxemia and IL-1 beta stimulate mucosal IL-6 production in different parts of the gastrointestinal tract.

7 January 2021

1 reference

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Nitric oxide inhibits LPS-induced IL-6 production in enterocytes

7 January 2021

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Multiple cytokines are required to induce hepatocyte nitric oxide production and inhibit total protein synthesis

7 January 2021

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Nitric oxide may upregulate in vivo hepatic protein synthesis during endotoxemia

7 January 2021

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The discovery of nitric oxide as the endogenous nitrovasodilator

7 January 2021

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Spontaneous release of interferon gamma by intestinal lamina propria lymphocytes in Crohn's disease. Kinetics of in vitro response to interferon gamma inducers

7 January 2021

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Signal transduction by tumor necrosis factor and gene regulation of the inflammatory cytokine interleukin-6.

7 January 2021

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The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter.

7 January 2021

1 reference

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Multiple nuclear factors interact with the immunoglobulin enhancer sequences

7 January 2021

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The NF-kappa B and I kappa B proteins: new discoveries and insights

7 January 2021

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NF-kappa B: ten years after

7 January 2021

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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

7 January 2021

1 reference

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IL-6 production in human intestinal epithelial cells following stimulation with IL-1 beta is associated with activation of the transcription factor NF-kappa B.

7 January 2021

1 reference

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Intestinal NF-kappaB is activated, mainly as p50 homodimers, by platelet-activating factor.

7 January 2021

1 reference

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Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa.

7 January 2021

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Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice

7 January 2021

1 reference

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Nuclear factor-kappaB is activated in intestinal mucosa during endotoxemia

7 January 2021

1 reference

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Activation of NF-kappaB varies in different regions of the gastrointestinal tract during endotoxemia.

7 January 2021

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IL-6-regulated transcription factors

7 January 2021

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The Role of C/EBP Isoforms in the Control of Inflammatory and Native Immunity Functions

7 January 2021

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Biological role of the CCAAT/enhancer-binding protein family of transcription factors

7 January 2021

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Regulation of CCAAT/enhancer binding protein isoforms by serum and glucocorticoids in the rat intestinal epithelial crypt cell line IEC-6.

7 January 2021

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Counter-regulatory effect of sodium butyrate on tumour necrosis factor-alpha (TNF-alpha)-induced complement C3 and factor B biosynthesis in human intestinal epithelial cells

7 January 2021

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Calcium channel blockers activate the interleukin-6 gene via the transcription factors NF-IL6 and NF-kappaB in primary human vascular smooth muscle cells

7 January 2021

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The transcription factor activator protein-1 is activated and interleukin-6 production is increased in interleukin-1beta-stimulated human enterocytes.

7 January 2021

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Transforming growth factor-beta1 induces interleukin-6 expression via activating protein-1 consisting of JunD homodimers in primary human lung fibroblasts.

7 January 2021

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Rapid activation of NF-kappaB and AP-1 and target gene expression in postischemic rat intestine

7 January 2021

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Sodium arsenite induces heat shock protein-72 kilodalton expression in the lungs and protects rats against sepsis

7 January 2021

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Effect of ethanol and sodium arsenite on HSP-72 formation and on survival in a murine endotoxin model.

7 January 2021

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The influence of heat shock protein 70 induction on hemodynamic variables in a porcine model of recurrent endotoxemia.

7 January 2021

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Clinical implications of the stress response

7 January 2021

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Effect of acute-phase and heat-shock stress on apoptosis in intestinal epithelial cells (Caco-2).

7 January 2021

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Induction of heat-shock protein 72 protects against ischemia/reperfusion in rat small intestine

7 January 2021

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Induction of the stress response increases interleukin-6 production in the intestinal mucosa of endotoxaemic mice

7 January 2021

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Induction of the stress response in vivo decreases nuclear factor-kappa B activity in jejunal mucosa of endotoxemic mice

7 January 2021

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Interleukin-6 production in human intestinal epithelial cells increases in association with the heat shock response

7 January 2021

1 reference

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Molecular aspects of arsenic stress

7 January 2021

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Arsenic inhibits NF-kappaB-mediated gene transcription by blocking IkappaB kinase activity and IkappaBalpha phosphorylation and degradation

7 January 2021

1 reference

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10.1016/S0002-9610(02)00812-7

7 January 2021

Identifiers

DOI

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3 August 2017

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