Alzheimer's disease: role of aging in pathogenesis (Q34614555)

3 August 2017

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title

Alzheimer's disease: role of aging in pathogenesis (English)

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3 August 2017

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Denham Harman

1

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3 August 2017

language of work or name

English

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publication date

1 April 2002

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Annals of the New York Academy of Sciences

3 August 2017

published in

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3 August 2017

volume

959

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3 August 2017

page(s)

384-95; discussion 463-5

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Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14

3 August 2017

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Distribution of Alzheimer-type pathologic changes in nondemented elderly individuals matches the pattern in Alzheimer's disease

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Mutations in mitochondrial cytochrome c oxidase genes segregate with late-onset Alzheimer disease

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The amyloid precursor protein of Alzheimer's disease is found on the surface of static but not activity motile portions of neurites.

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The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin

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Three-dimensional map of the plasma membrane H+-ATPase in the open conformation.

21 January 2018

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The mechanism of Ca2+ transport by sarco(endo)plasmic reticulum Ca2+-ATPases

21 January 2018

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The control of neuronal Ca2+ homeostasis

21 January 2018

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Inositol phosphates and cell signalling

21 January 2018

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Inhibition of the skeletal muscle ryanodine receptor calcium release channel by nitric oxide.

21 January 2018

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Phospholamban regulates the Ca2+-ATPase through intramembrane interactions

21 January 2018

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An investigation of the mechanism of inhibition of the Ca(2+)-ATPase by phospholamban

21 January 2018

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Antagonistic effect of ganglioside GM1 and GM3 on the activity and conformation of sarcoplasmic reticulum Ca(2+)-ATPase

21 January 2018

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Alteration of acylphosphatase levels in familial Alzheimer's disease fibroblasts with presenilin gene mutations.

21 January 2018

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Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: reduced oxidative stress and preserved mitochondrial function

21 January 2018

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Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation.

21 January 2018

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21 January 2018

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Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease.

21 January 2018

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Increased mitochondrial superoxide generation in neurons from trisomy 16 mice: a model of Down's syndrome

21 January 2018

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Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro.

21 January 2018

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The association between head trauma and Alzheimer's disease

21 January 2018

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The occult aftermath of boxing

21 January 2018

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Neurological sequelae of boxing

21 January 2018

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21 January 2018

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The cerebral vasculature in dementia pugilistica

21 January 2018

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Hydrogen peroxide mediates amyloid beta protein toxicity

21 January 2018

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Prospects for pharmacological intervention in Alzheimer disease

21 January 2018

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A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study.

21 January 2018

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Neuroprotection by the metabolic antioxidant alpha-lipoic acid

21 January 2018

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Vitamin C crosses the blood-brain barrier in the oxidized form through the glucose transporters

21 January 2018

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Propofol hemisuccinate protects neuronal cells from oxidative injury

21 January 2018

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The elusive function of metallothioneins

21 January 2018

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Enhanced neurotrophic activity in Alzheimer's disease cortex is not associated with down-regulation of metallothionein-III (GIF).

21 January 2018

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31P NMR study of improvement in oxidative phosphorylation by vitamins K3 and C in a patient with a defect in electron transport at complex III in skeletal muscle.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02109.X

Clinical trial of indomethacin in Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02109.X

Inverse association of anti-inflammatory treatments and Alzheimer's disease: initial results of a co-twin control study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02109.X

Inflammation and Alzheimer's disease pathogenesis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02109.X

Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02109.X

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02109.X

A substrate-based difluoro ketone selectively inhibits Alzheimer's gamma-secretase activity.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02109.X

Risky apolipoprotein in brain

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02109.X

Structure of the calcium pump from sarcoplasmic reticulum at 8-Å resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02109.X

10.1111/J.1749-6632.2002.TB02109.X

21 January 2018

Identifiers

DOI

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3 August 2017

1 reference