Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial (Q34622955)

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English	Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial (English)

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Europe PubMed Central

PubMed publication ID

3 August 2017

single-nucleotide polymorphism

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based on heuristic

inferred from title

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based on heuristic

inferred from title

acute coronary syndrome

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Bryan J Barratt

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Bryan J Barratt

5

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Robert F. Storey

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Robert F Storey

3

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1

object named as

Lars Wallentin

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Europe PubMed Central

PubMed publication ID

3 August 2017

8

object named as

Hugo Katus

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Europe PubMed Central

PubMed publication ID

3 August 2017

author name string

Stefan James

2

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Europe PubMed Central

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3 August 2017

Martin Armstrong

4

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Europe PubMed Central

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3 August 2017

Jay Horrow

6

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Europe PubMed Central

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3 August 2017

Steen Husted

7

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Europe PubMed Central

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3 August 2017

P Gabriel Steg

9

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Europe PubMed Central

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3 August 2017

Svati H Shah

10

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Europe PubMed Central

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3 August 2017

Richard C Becker

11

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Europe PubMed Central

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3 August 2017

PLATO investigators

12

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3 August 2017

language of work or name

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publication date

1 October 2010

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Europe PubMed Central

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3 August 2017

number of pages

9

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3 August 2017

376

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3 August 2017

9749

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3 August 2017

1320-1328

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PubMed publication ID

3 August 2017

ACC/AHA 2007 guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Rev

1 reference

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7 January 2021

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inferred from DOI database lookup

Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes

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https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2961274-3

7 January 2021

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2009 Focused Updates: ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction (updating the 2004 Guideline and 2007 Focused Update) and ACC/AHA/SCAI Guidelines on Percutaneous Coronary Intervention (updating the 200

1 reference

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7 January 2021

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Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: The Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology:

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7 January 2021

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Prasugrel versus clopidogrel in patients with acute coronary syndromes

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https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2961274-3

7 January 2021

based on heuristic

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Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects

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Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis

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Cytochrome p-450 polymorphisms and response to clopidogrel

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7 January 2021

based on heuristic

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Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy

1 reference

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7 January 2021

based on heuristic

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Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease

1 reference

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7 January 2021

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Assessment of P2Y(12) inhibition with the point-of-care device VerifyNow P2Y12 in patients treated with prasugrel or clopidogrel coadministered with aspirin

1 reference

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7 January 2021

based on heuristic

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Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study

1 reference

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based on heuristic

inferred from DOI database lookup

Cardiovascular risk in clopidogrel-treated patients according to cytochrome P450 2C19*2 loss-of-function allele or proton pump inhibitor coadministration: a systematic meta-analysis

1 reference

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based on heuristic

inferred from DOI database lookup

Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement

1 reference

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based on heuristic

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Impact of P-glycoprotein on clopidogrel absorption

1 reference

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based on heuristic

inferred from DOI database lookup

Genetic determinants of response to clopidogrel and cardiovascular events

1 reference

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Pharmacodynamics, pharmacokinetics, and safety of the oral reversible P2Y12 antagonist AZD6140 with aspirin in patients with atherosclerosis: a double-blind comparison to clopidogrel with aspirin

1 reference

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Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study.

1 reference

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7 January 2021

based on heuristic

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Ticagrelor yields consistent dose-dependent inhibition of ADP-induced platelet aggregation in patients with atherosclerotic disease regardless of genotypic variations in P2RY12, P2RY1, and ITGB3.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2961274-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Ticagrelor versus clopidogrel in patients with acute coronary syndromes

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2961274-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparison of ticagrelor, the first reversible oral P2Y(12) receptor antagonist, with clopidogrel in patients with acute coronary syndromes: Rationale, design, and baseline characteristics of the PLATelet inhibition and patient Outcomes (PLATO) tria

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular basis of ethnic differences in drug disposition and response

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2961274-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Need for reassessment of reported CYP2C19 allele frequencies in various populations in view of CYP2C19*17 discovery: the case of Greece.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity

1 reference

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7 January 2021

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inferred from DOI database lookup

Cytochrome P450 genetic polymorphisms and the response to prasugrel: relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes

1 reference

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Relation of cytochrome P450 2C19 loss-of-function polymorphism to occurrence of drug-eluting coronary stent thrombosis.

1 reference

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Cytochrome P450 2C19 loss-of-function polymorphism and stent thrombosis following percutaneous coronary intervention

1 reference

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Cytochrome P450 2C19 681G>A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stents

1 reference

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based on heuristic

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Relationship between the C3435T and G2677T(A) polymorphisms in the ABCB1 gene and P-glycoprotein expression in human liver

1 reference

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Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

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Pharmacogenetics in cardiovascular antithrombotic therapy

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inferred from DOI database lookup

Identifiers

10.1016/S0140-6736(10)61274-3

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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