Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity (Q34631498)

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English	Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity	scientific article

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity (English)

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Europe PubMed Central

3 August 2017

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Human Induced Pluripotent Stem Cells

1 reference

based on heuristic

inferred from title

Robert C. Robbins

13

object named as

Robert C Robbins

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Europe PubMed Central

3 August 2017

14

object named as

Joseph C Wu

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Europe PubMed Central

3 August 2017

Veronica Sanchez-Freire

5

object named as

Veronica Sanchez-Freire

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Europe PubMed Central

3 August 2017

author name string

Ping Liang

1

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Europe PubMed Central

3 August 2017

Feng Lan

2

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Europe PubMed Central

3 August 2017

Andrew S Lee

3

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Europe PubMed Central

3 August 2017

Tingyu Gong

4

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Europe PubMed Central

3 August 2017

Yongming Wang

6

1 reference

Europe PubMed Central

3 August 2017

Sebastian Diecke

7

1 reference

Europe PubMed Central

3 August 2017

Karim Sallam

8

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Europe PubMed Central

3 August 2017

Joshua W Knowles

9

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Europe PubMed Central

3 August 2017

Paul J Wang

10

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Europe PubMed Central

3 August 2017

Patricia K Nguyen

11

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3 August 2017

Donald M Bers

12

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3 August 2017

language of work or name

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publication date

21 March 2013

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3 August 2017

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Europe PubMed Central

3 August 2017

127

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16

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3 August 2017

1677-1691

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3 August 2017

describes a project that uses

induced pluripotent stem cell

1 reference

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inferred from title

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3870148/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells

1 reference

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7 July 2018

Modeling of catecholaminergic polymorphic ventricular tachycardia with patient-specific human-induced pluripotent stem cells

1 reference

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7 July 2018

Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy.

1 reference

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Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia

1 reference

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Electrophysiological characterization of cardiomyocytes derived from human induced pluripotent stem cells

1 reference

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Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development

1 reference

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Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation

1 reference

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Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome

1 reference

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Modelling the long QT syndrome with induced pluripotent stem cells

1 reference

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Patient-specific induced pluripotent stem-cell models for long-QT syndrome

1 reference

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Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

1 reference

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Non-cardiovascular drugs that inhibit hERG-encoded potassium channels and risk of sudden cardiac death

1 reference

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Quantified proarrhythmic potential of selected human embryonic stem cell-derived cardiomyocytes.

1 reference

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The action potential and comparative pharmacology of stem cell-derived human cardiomyocytes

1 reference

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A nonviral minicircle vector for deriving human iPS cells

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Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes

1 reference

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Cardiomyocyte differentiation of human induced pluripotent stem cells

1 reference

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Drug-induced QT interval shortening: potential harbinger of proarrhythmia and regulatory perspectives

1 reference

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Predicting drug-induced changes in QT interval and arrhythmias: QT-shortening drugs point to gaps in the ICHS7B Guidelines

1 reference

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Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population

1 reference

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The molecular basis of chloroquine block of the inward rectifier Kir2.1 channel

1 reference

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Alfuzosin delays cardiac repolarization by a novel mechanism

1 reference

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Strategies to reduce late-stage drug attrition due to mitochondrial toxicity

1 reference

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Drug-induced long QT and torsade de pointes: recent advances

1 reference

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Are hERG channel inhibition and QT interval prolongation all there is in drug-induced torsadogenesis? A review of emerging trends

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Embryonic stem cells in drug discovery

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The impact of drug-induced QT interval prolongation on drug discovery and development

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Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development

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International Conference on Harmonisation; guidance on S7A safety pharmacology studies for human pharmaceuticals; availability. Notice.

1 reference

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The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model

1 reference

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Pharmacogenetics and drug-induced arrhythmias

1 reference

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Molecular and cellular mechanisms of cardiac arrhythmias

1 reference

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Mechanisms and management of proarrhythmia

1 reference

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Progressive maturation in contracting cardiomyocytes derived from human embryonic stem cells: Qualitative effects on electrophysiological responses to drugs

1 reference

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In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes

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26 October 2018

Molecular basis of species-specific expression of repolarizing K+ currents in the heart.

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Adverse drug events in hospitalized patients. Excess length of stay, extra costs, and attributable mortality.

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Effects of a K(+) channel opener to reduce transmural dispersion of repolarization and prevent torsade de pointes in LQT1, LQT2, and LQT3 models of the long-QT syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519760

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Contraindicated use of cisapride: impact of food and drug administration regulatory action

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519760

12 December 2020

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Sudden Death in Noncoronary Heart Disease Is Associated With Delayed Paced Ventricular Activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519760

12 December 2020

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Population-Based Studies of Adverse Drug Effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519760

12 December 2020

based on heuristic

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Potassium channel openers are likely to be proarrhythmic in the diseased human heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519760

12 December 2020

based on heuristic

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Anti-HERG activity and the risk of drug-induced arrhythmias and sudden death

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519760

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519760

12 December 2020

based on heuristic

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Identifiers

10.1161/CIRCULATIONAHA.113.001883

1 reference

Europe PubMed Central

3 August 2017

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Europe PubMed Central

3 August 2017

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Europe PubMed Central

3 August 2017

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