Dysregulated expression of both the costimulatory CD28 and inhibitory CTLA-4 molecules in PB T cells of advanced cervical cancer patients suggests systemic immunosuppression related to disease progression (Q34633776)

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English	Dysregulated expression of both the costimulatory CD28 and inhibitory CTLA-4 molecules in PB T cells of advanced cervical cancer patients suggests systemic immunosuppression related to disease progression	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Dysregulated expression of both the costimulatory CD28 and inhibitory CTLA-4 molecules in PB T cells of advanced cervical cancer patients suggests systemic immunosuppression related to disease progression (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

immunosuppression

1 reference

based on heuristic

inferred from title

cervix uterine cancer

1 reference

based on heuristic

inferred from title

Agata Kosmaczewska

1

object named as

Agata Kosmaczewska

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

3

object named as

Lidia Ciszak

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

8

object named as

Irena Frydecka

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

5

object named as

Jan Kornafel

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

author name string

Dorota Bocko

2

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Iwona Wlodarska-Polinska

4

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Aleksandra Szteblich

6

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Anna Masternak

7

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

publication date

19 November 2011

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Pathology Oncology Research

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

18

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

479-489

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer

1 reference

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Improved prognostic classification of breast cancer defined by antagonistic activation patterns of immune response pathway modules

1 reference

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7 July 2018

CD3zeta expression and T cell proliferation are inhibited by TGF-beta1 and IL-10 in cervical cancer patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

7 July 2018

Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade

1 reference

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7 July 2018

Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections.

1 reference

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7 July 2018

New approach reveals CD28 and IFNG gene interaction in the susceptibility to cervical cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

7 July 2018

The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

7 July 2018

TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells

1 reference

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Neopterin as an indicator of immune activation and prognosis in patients with gynecological malignancies

1 reference

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7 July 2018

Overlap between molecular markers expressed by naturally occurring CD4+CD25+ regulatory T cells and antigen specific CD4+CD25+ and CD8+CD28- T suppressor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

7 July 2018

Alterations of the expression of T-cell-related costimulatory CD28 and downregulatory CD152 (CTLA-4) molecules in patients with B-cell chronic lymphocytic leukaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

7 July 2018

Inflammation and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

7 July 2018

Correlation of blood lymphocyte CTLA-4 (CD152) induction in Hodgkin's disease with proliferative activity, interleukin 2 and interferon-gamma production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

7 July 2018

Down-regulation of CD28 expression by TNF-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

7 July 2018

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

7 July 2018

Tumor necrosis factor-alpha promotes human papillomavirus (HPV) E6/E7 RNA expression and cyclin-dependent kinase activity in HPV-immortalized keratinocytes by a ras-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

7 July 2018

Natural killer cells and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

7 July 2018

Requirement for recognition of class II molecules and processed tumor antigen for optimal generation of syngeneic tumor-specific class I-restricted CTL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

7 July 2018

Role of the CD28 receptor in T-cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

7 July 2018

Increased age and mortality associated with cervical carcinomas negative for human papillomavirus RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

7 July 2018

Rapidly progressing cervical cancer in a patient with human immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1007%2FS12253-011-9471-Y

21 January 2018

The cellular response associated with cervical intraepithelial neoplasia in HIV+ and HIV- subjects

1 reference

https://api.crossref.org/works/10.1007%2FS12253-011-9471-Y

21 January 2018

Reduced local immunity in HPV-related VIN: expression of chemokines and involvement of immunocompetent cells

1 reference

https://api.crossref.org/works/10.1007%2FS12253-011-9471-Y

21 January 2018

Peripheral human CD8(+)CD28(+)T lymphocytes give rise to CD28(-)progeny, but IL-4 prevents loss of CD28 expression.

1 reference

https://api.crossref.org/works/10.1007%2FS12253-011-9471-Y

21 January 2018

CTLA-4 gene expression is influenced by promoter and exon 1 polymorphisms

1 reference

https://api.crossref.org/works/10.1007%2FS12253-011-9471-Y

21 January 2018

CTLA-4 gene and susceptibility to human papillomavirus-16-associated cervical squamous cell carcinoma in Taiwanese women.

1 reference

https://api.crossref.org/works/10.1007%2FS12253-011-9471-Y

21 January 2018

Generation of highly suppressive adaptive CD8(+)CD25(+)FOXP3(+) regulatory T cells by continuous antigen stimulation

1 reference

https://api.crossref.org/works/10.1007%2FS12253-011-9471-Y

21 January 2018

Nonantigen specific CD8+ T suppressor lymphocytes originate from CD8+CD28- T cells and inhibit both T-cell proliferation and CTL function.

1 reference

https://api.crossref.org/works/10.1007%2FS12253-011-9471-Y

21 January 2018

Differentiation of naive CD4+ T cells into CD4+CD25+FOXP3+ regulatory T cells by continuous antigen stimulation.

1 reference

https://api.crossref.org/works/10.1007%2FS12253-011-9471-Y

21 January 2018

Cytokine production patterns in cervical intraepithelial neoplasia: association with human papillomavirus infection.

1 reference

https://api.crossref.org/works/10.1007%2FS12253-011-9471-Y

21 January 2018

Enhanced interferon-gamma by CD8+ CD28- lymphocytes from HIV+ patients

1 reference

https://api.crossref.org/works/10.1007%2FS12253-011-9471-Y

21 January 2018

CD8 regulatory T cells: what's old is now new.

1 reference

https://api.crossref.org/works/10.1007%2FS12253-011-9471-Y

21 January 2018

Interaction of immunological genes on chromosome 2q33 and IFNG in susceptibility to cervical cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

26 October 2018

Influence of CTLA-4/CD28/ICOS gene polymorphisms on the susceptibility to cervical squamous cell carcinoma and stage of differentiation in the Polish population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

26 October 2018

Frequencies and role of regulatory T cells in patients with (pre)malignant cervical neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

26 October 2018

Increased expression of CD152 (CTLA-4) by normal T lymphocytes in untreated patients with B-cell chronic lymphocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

26 October 2018

Relative expression levels of Th1 and Th2 cytokine mRNA are independent prognostic factors in patients with ovarian cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

26 October 2018

CTLA-4 (CD152) can inhibit T cell activation by two different mechanisms depending on its level of cell surface expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

26 October 2018

Expression of costimulatory molecules CD80 and CD86 and their receptors CD28, CTLA-4 on malignant ascites CD3+ tumour-infiltrating lymphocytes (TIL) from patients with ovarian and other types of peritoneal carcinomatosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

26 October 2018

CD28 engagement by B7/BB-1 induces transient down-regulation of CD28 synthesis and prolonged unresponsiveness to CD28 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313031

26 October 2018

Prognostic Value of Intratumoral Interferon Gamma Messenger RNA Expression in Invasive Cervical Carcinomas

1 reference

https://api.crossref.org/works/10.1007%2FS12253-011-9471-Y

21 January 2018

Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal Cancer

1 reference

https://api.crossref.org/works/10.1007%2FS12253-011-9471-Y

21 January 2018

CD8+CD28- cells and CD4+CD25+ regulatory T cells in the peripheral blood of advanced stage lung cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22094905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluations of interferon-γ/interleukin-4 ratio and neutrophil/lymphocyte ratio as prognostic indicators in gastric cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22094905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of CD28 expression on CD8(+) T cells is induced by IL-2 receptor gamma chain signalling cytokines and type I IFN, and increases susceptibility to activation-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22094905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NK cell activity in the presence of IL-12 is a prognostic assay to neoadjuvant chemotherapy in cervical cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22094905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single nucleotide polymorphism in the first intron of the human IFN-gamma gene: absolute correlation with a polymorphic CA microsatellite marker of high IFN-gamma production

1 reference

https://pubmed.ncbi.nlm.nih.gov/22094905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor-infiltrating lymphocytes contain higher numbers of type 1 cytokine expressors and DR+ T cells compared with lymphocytes from tumor draining lymph nodes and peripheral blood in patients with cancer of the uterine cervix

1 reference

https://pubmed.ncbi.nlm.nih.gov/22094905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavior of mild cervical dysplasia during long-term follow-up

1 reference

https://pubmed.ncbi.nlm.nih.gov/22094905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between HLA-expression and infiltration of immune cells in cervical carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22094905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulating serum levels of cytokines and angiogenic factors in patients with cervical cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22094905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alteration of signal-transducing molecules and phenotypical characteristics in peripheral blood lymphocytes from gastric carcinoma patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22094905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased secretion patterns of interleukin-10 and tumor necrosis factor-alpha in cervical squamous intraepithelial lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22094905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of human papillomavirus type 16-specific immunologic responses in a normal and an human papillomavirus-infected populations

1 reference

https://pubmed.ncbi.nlm.nih.gov/22094905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic significance of T helper 1 and 2 and T cytotoxic 1 and 2 cells in patients with non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22094905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of tumor-derived proinflammatory cytokines GM-CSF, TNF-α, and IL-12 in the migration and differentiation of antigen-presenting cells in cervical carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22094905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12253-011-9471-Y

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

ResearchGate publication ID

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