Cytotoxicity issues pertinent to lipoplex-mediated gene therapy in-vivo (Q34634385)

3 August 2017

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title

Cytotoxicity issues pertinent to lipoplex-mediated gene therapy in-vivo (English)

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3 August 2017

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Crispin R Dass

1

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3 August 2017

1 May 2002

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Journal of Pharmacy and Pharmacology

3 August 2017

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3 August 2017

54

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3 August 2017

593-601

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3 August 2017

5

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A novel tetraester construct that reduces cationic lipid-associated cytotoxicity. Implications for the onset of cytotoxicity

3 August 2017

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

The Cell Biology of Macrophage Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Gene transfer in vitro and in vivo by cationic lipids is not significantly affected by levels of supercoiling of a reporter plasmid

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using starburst PAMAM dendrimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Enhanced in vitro and in vivo cationic lipid-mediated gene delivery with a fluorinated glycerophosphoethanolamine helper lipid

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Activation of host antitumoral responses by cationic lipid/DNA complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Co-polymer of histidine and lysine markedly enhances transfection efficiency of liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

New cationic liposomes for gene transfer into mammalian cells with high efficiency and low toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Use of perfluorocarbon (fluorinert) to enhance reporter gene expression following intratracheal instillation into the lungs of Balb/c mice: implications for nebulized delivery of plasmids

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Lipoplexes and tumours. A review

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Delivery of lipoplexes for genotherapy of solid tumours: role of vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

A microsphere-liposome (microplex) vector for targeted gene therapy of cancer. II. In vivo biodistribution study in a solid tumor model

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Liposomes containing cationic dimethyl dioctadecyl ammonium bromide: formulation, quality control, and lipofection efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Anti-inflammatory activity of cationic lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Toxicity and immunomodulatory activity of liposomal vectors formulated with cationic lipids toward immune effector cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Thermosensitive liposomes: extravasation and release of contents in tumor microvascular networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

A placebo-controlled study of liposome-mediated gene transfer to the nasal epithelium of patients with cystic fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Stabilization of cationic liposome-plasmid DNA complexes by polyamines and poly(ethylene glycol)-phospholipid conjugates for efficient in vivo gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Cationic liposome-mediated E1A gene transfer to human breast and ovarian cancer cells and its biologic effects: a phase I clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Phase I study of immunotherapy of cutaneous metastases of human carcinoma using allogeneic and xenogeneic MHC DNA-liposome complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Liver-targeted gene transfer into a human hepatoblastoma cell line and in vivo by sterylglucoside-containing cationic liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

A lipid carrier with a membrane active component and a small complex size are required for efficient cellular delivery of anti-sense phosphorothioate oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Comparison of cell proliferation and toxicity assays using two cationic liposomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Fate of cationic liposomes and their complex with oligonucleotide in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Contribution of plasmid DNA to hepatotoxicity after systemic administration of lipoplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Size-dependent DNA mobility in cytoplasm and nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Efficacy of cationic liposome-mediated gene transfer to mesangial cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Cationic liposome-mediated gene delivery to the liver and to hepatocellular carcinomas in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Safety and toxicity of catheter gene delivery to the pulmonary vasculature in a patient with metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA-liposome complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Liposome-mediated gene transfer into human vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Efficiency and toxicity of liposome-mediated gene transfer to corneal endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Promoter attenuation in gene therapy: interferon-gamma and tumor necrosis factor-alpha inhibit transgene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

A clinical inflammatory syndrome attributable to aerosolized lipid-DNA administration in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: physicochemical and transfection studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Interaction between DNA-cationic liposome complexes and erythrocytes is an important factor in systemic gene transfer via the intravenous route in mice: the role of the neutral helper lipid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Interaction of positively-charged liposomes with blood: implications for their application in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Gene therapy for cystic fibrosis using cationic liposome mediated gene transfer: a phase I trial of safety and efficacy in the nasal airway

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

A novel, long-circulating, and functional liposomal formulation of antisense oligodeoxynucleotides targeted against MDR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Mechanism of lipoplex gene delivery in mouse lung: binding and internalization of fluorescent lipid and DNA components

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

A multi-step lipid mixing assay to model structural changes in cationic lipoplexes used for in vitro transfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Immunoliposome-mediated gene transfer into cultured myotubes

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

A novel cationic lipid greatly enhances plasmid DNA delivery and expression in mouse lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

LPD lipopolyplex initiates a potent cytokine response and inhibits tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

beta-Galactosidase staining following intracoronary infusion of cationic liposomes in the in vivo rabbit heart is produced by microinfarction rather than effective gene transfer: a cautionary tale

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Preclinical and clinical study of HER-2/neu-targeting cancer gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

In vivo gene therapy with a cationic polymer markedly enhances the antitumor activity of antiangiogenic genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Overcoming the inhibitory effect of serum on lipofection by increasing the charge ratio of cationic liposome to DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Time-dependent maturation of cationic liposome-DNA complex for serum resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Cellular and molecular barriers to gene transfer by a cationic lipid

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357021778817

21 January 2018

Identifiers

DOI

10.1211/0022357021778817

1 reference

release_7yketkuw2fef3mrzcqxzfbqjmm

3 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7yketkuw2fef3mrzcqxzfbqjmm

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

12005353

1 reference

PubMed ID

12005353