Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity (Q34634421)

3 August 2017

Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity (English)

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3 August 2017

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mitochondrial fission

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Wenjun Song

1

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Géraldine Liot

Geraldine Liot

4

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Isabelle Rouiller

Isabelle Rouiller

13

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Mahmoud A. Pouladi

Mahmoud A Pouladi

9

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Michael R. Hayden

Michael R Hayden

10

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Eliezer Masliah

11

Eliezer Masliah

1 reference

3 August 2017

Robert Schwarzenbacher

14

Robert Schwarzenbacher

1 reference

3 August 2017

Jin Chen

2

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3 August 2017

Alejandra Petrilli

3

1 reference

3 August 2017

Eva Klinglmayr

5

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3 August 2017

Yue Zhou

6

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3 August 2017

Patrick Poquiz

7

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3 August 2017

Jonathan Tjong

8

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3 August 2017

Mark Ellisman

12

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3 August 2017

Blaise Bossy

15

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3 August 2017

Guy Perkins

16

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3 August 2017

Ella Bossy-Wetzel

17

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3 August 2017

language of work or name

English

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publication date

20 February 2011

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3 August 2017

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3 August 2017

17

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3 August 2017

377-382

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3 August 2017

3

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https://scigraph.springernature.com/pub.10.1038/nm.2313

3 August 2017

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cites work

S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Interaction of postsynaptic density protein-95 with NMDA receptors influences excitotoxicity in the yeast artificial chromosome mouse model of Huntington's disease.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Complex II inhibition by 3-NP causes mitochondrial fragmentation and neuronal cell death via an NMDA- and ROS-dependent pathway.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Differential susceptibility to excitotoxic stress in YAC128 mouse models of Huntington disease between initiation and progression of disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Impairing the mitochondrial fission and fusion balance: a new mechanism of neurodegeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Effects of overexpression of huntingtin proteins on mitochondrial integrity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Mutant huntingtin and mitochondrial dysfunction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Visualization of dynamins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Mitochondrial fragmentation in neurodegeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Huntingtin interacting proteins are genetic modifiers of neurodegeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Mdv1 interacts with assembled dnm1 to promote mitochondrial division

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Huntingtin-protein interactions and the pathogenesis of Huntington's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Human huntingtin derived from YAC transgenes compensates for loss of murine huntingtin by rescue of the embryonic lethal phenotype

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051025

Mitochondrial fission is an upstream and required event for bax foci formation in response to nitric oxide in cortical neurons.

7 July 2018

1 reference

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease

21 January 2018

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Electron tomography of mitochondria after the arrest of protein import associated with Tom19 depletion

21 January 2018

1 reference

Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.

21 January 2018

1 reference

Activated mitofusin 2 signals mitochondrial fusion, interferes with Bax activation, and reduces susceptibility to radical induced depolarization

21 January 2018

1 reference

DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans

21 January 2018

1 reference

Electron tomographic analysis of cytoskeletal cross-bridges in the paranodal region of the node of Ranvier in peripheral nerves

21 January 2018

1 reference

A continuous, regenerative coupled GTPase assay for dynamin-related proteins

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1038/NM.2313

1 reference

Dimensions Publication ID

3 August 2017

1004669874

0 references

Fatcat ID

release_bcrwpmrlofdoxpayh7g52b35tu

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bcrwpmrlofdoxpayh7g52b35tu

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

3051025

1 reference

3 August 2017

1 reference