PPARγ agonists enhance ET-743-induced adipogenic differentiation in a transgenic mouse model of myxoid round cell liposarcoma (Q34635550)

3 August 2017

title

PPARγ agonists enhance ET-743-induced adipogenic differentiation in a transgenic mouse model of myxoid round cell liposarcoma (English)

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3 August 2017

6

Carlos Cordon-Cardo

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3 August 2017

8

Igor Matushansky

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3 August 2017

Elizabeth Charytonowicz

1

object named as

Elizabeth Charytonowicz

1 reference

3 August 2017

Melissa Terry

2

1 reference

3 August 2017

Katherine Coakley

3

1 reference

3 August 2017

Leonid Telis

4

1 reference

3 August 2017

Fabrizio Remotti

5

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3 August 2017

Robert N Taub

7

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3 August 2017

language of work or name

English

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publication date

1 February 2012

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Journal of Clinical Investigation

3 August 2017

published in

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3 August 2017

volume

122

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3 August 2017

issue

3

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3 August 2017

page(s)

886-898

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FUS-CHOP fusion protein expression coupled to p53 deficiency induces liposarcoma in mouse but not in human adipose-derived mesenchymal stem/stromal cells.

3 August 2017

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7 July 2018

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7 July 2018

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7 July 2018

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Trabectedin (ET-743) promotes differentiation in myxoid liposarcoma tumors

7 July 2018

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FUS-DDIT3 prevents the development of adipocytic precursors in liposarcoma by repressing PPARgamma and C/EBPalpha and activating eIF4E.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: a retrospective study

7 July 2018

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7 July 2018

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The myxoid/round cell liposarcoma fusion oncogene FUS-DDIT3 and the normal DDIT3 induce a liposarcoma phenotype in transfected human fibrosarcoma cells

7 July 2018

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7 July 2018

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Frequent alteration of p16(INK4a)/p14(ARF) and p53 pathways in the round cell component of myxoid/round cell liposarcoma: p53 gene alterations and reduced p14(ARF) expression both correlate with poor prognosis.

7 July 2018

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Transcriptional signature of Ecteinascidin 743 (Yondelis, Trabectedin) in human sarcoma cells explanted from chemo-naive patients.

7 July 2018

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Comparable transforming capacities and differential gene expression patterns of variant FUS/CHOP fusion transcripts derived from soft tissue liposarcomas

7 July 2018

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7 July 2018

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7 July 2018

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Prognostic impact of P53 status, TLS-CHOP fusion transcript structure, and histological grade in myxoid liposarcoma: a molecular and clinicopathologic study of 82 cases.

7 July 2018

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Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma

7 July 2018

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Terminal differentiation of human breast cancer through PPAR gamma

7 July 2018

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Molecular aberrations of the G1-S checkpoint in myxoid and round cell liposarcoma

7 July 2018

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Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor.

7 July 2018

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7 July 2018

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Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

7 July 2018

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7 July 2018

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26 October 2018

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EWS-FLI-1 expression triggers a Ewing's sarcoma initiation program in primary human mesenchymal stem cells.

26 October 2018

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Expression of the FUS-CHOP fusion protein in primary mesenchymal progenitor cells gives rise to a model of myxoid liposarcoma.

26 October 2018

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26 October 2018

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Extreme sensitivity to Yondelis® (Trabectedin, ET-743) in low passaged sarcoma cell lines correlates with mutated p53

26 October 2018

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Liposarcoma initiated by FUS/TLS-CHOP: the FUS/TLS domain plays a critical role in the pathogenesis of liposarcoma

9 December 2018

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12 December 2020

Expression of Cre recombinase in the developing mouse limb bud driven by aPrxl enhancer

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12 December 2020

Ecteinascidin-743, a new marine natural product with potent antitumor activity on human ovarian carcinoma xenografts

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12 December 2020

Limited role of TP53 and TP53-related genes in myxoid liposarcoma

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12 December 2020

Fat-specific FUS-DDIT3-transgenic mice establish PPAR inactivation is required to liposarcoma development

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12 December 2020

Molecular abnormalities of p53, MDM2, and H-ras in synovial sarcoma

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12 December 2020

Identifiers

DOI

10.1172/JCI60015

1 reference

3 August 2017

1 reference

3 August 2017

1 reference