Pharmacologic approaches to protection against radiation-induced lethality and other damage (Q34638214)

3 August 2017

3 references

19 June 2019

12 November 2019

1 December 2020

Pharmacologic approaches to protection against radiation-induced lethality and other damage (English)

1 reference

organic compound, having C-P covalent bound

3 August 2017

3 references

19 June 2019

12 November 2019

1 December 2020

1 reference

12 November 2019

1 reference

1 reference

1 December 2020

radiation protection agent

1 reference

1 December 2020

Weiss JF

1

1 reference

3 August 2017

1 December 1997

5 references

3 August 2017

19 June 2019

12 November 2019

20 September 2020

1 December 2020

6

1 reference

Environmental Health Perspectives

inferred from page(s)

published in

5 references

3 August 2017

19 June 2019

12 November 2019

20 September 2020

1 December 2020

105 Suppl 6

1 reference

3 August 2017

1473-1478

1 reference

Modulation with cytokines of radiation injury: suggested mechanisms of action

3 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Hypotensive mechanisms of amifostine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Protection of Normal Tissue from the Cytotoxic Effects of Chemotherapy and Radiation by Amifostine: Clinical Experiences

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Clastogenic factors in the plasma of Chernobyl accident recovery workers: anticlastogenic effect of Ginkgo biloba extract

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Inhibition of radiation carcinogenesis in mice by S-2-(3-aminopropylamino)-ethylphosphorothioic acid

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Radiation-Protective Agents in Mammals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Selenium and vitamin E inhibit radiogenic and chemically induced transformation in vitro via different mechanisms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Rationale and strategies for chemoprevention of cancer in humans.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Behavioral radioprotection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

From endotoxins to newer immunomodulators: survival-promoting effects of microbial polysaccharide complexes in irradiated animals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Increased radioprotection attained by DNA repair enhancement

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Bioavailability and newer methods of delivery of phosphorothioate radioprotectors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Can WR-2721 be improved upon?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Effect of the radioprotector WR-2721 on operant behavior in the rat.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Protection by WR-151327 against late-effect damage from fission-spectrum neutrons.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Protection against late effects of radiation by S-2-(3-aminopropylamino)-ethylphosphorothioic acid

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Comparison of behavioral and radioprotective effects of WR-2721 and WR-3689.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

The radioprotector WR-2721 reduces neutron-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in mouse splenocytes when administered prior to or following irradiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

A Phase I study of WR-2721 in combination with total body irradiation (TBI) in patients with refractory lymphoid malignancies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Behavioral toxicity of selected radioprotectors.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Total body irradiation prior to bone marrow transplantation: efficacy and safety of granisetron in the prophylaxis and control of radiation-induced emesis.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Misoprostol-induced radioprotection of oncogenic transformation.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Morbidity and mortality reduction by supplemental vitamin A or beta-carotene in CBA mice given total-body gamma-radiation.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Chemoprotection against Three Modes of Radiation Death in the Mouse

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Protection by WR-2721 of human bone marrow function following irradiation

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469917

Comparative behavioral toxicity of four sulfhydryl radioprotective compounds in mice: WR-2721, cysteamine, diethyldithiocarbamate, and N-acetylcysteine

26 October 2018

1 reference

12 December 2020

Cysteine Protection against X Irradiation

1 reference

12 December 2020

Advances in radioprotection through the use of combined agent regimens

1 reference

12 December 2020

Enhancement of topoisomerase I-mediated unwinding of supercoiled DNA by the radioprotector WR-33278

1 reference

12 December 2020

Postirradiation treatment with granulocyte colony-stimulating factor and preirradiation WR-2721 administration synergize to enhance hemopoietic reconstitution and increase survival

1 reference

12 December 2020

Radioprotection by vitamin E: Injectable vitamin E administered alone or with WR-3689 enhances survival of irradiated mice

1 reference

12 December 2020

Mechanism of Action of Aminothiol Radioprotectors

1 reference

12 December 2020

Prediction of the Effective Radioprotective Dose of WR-2721 in Humans through an Interspecies Tissue Distribution Study

1 reference

12 December 2020

Behavioral toxicity and efficacy of WR-2721 as a radioprotectant

1 reference

12 December 2020

Pathological evaluation of WR-151327 administered orally in irradiated and non-irradiated male mice

1 reference

12 December 2020

Protective effects of vitamins C and E against gamma-ray-induced chromosomal damage in mouse

1 reference

12 December 2020

Protection against radiation-induced mutagenesis at the hprt locus by spermine and N,N"-(dithiodi-2,1-ethanediyl)bis-1,3-propanediamine (WR-33278)

1 reference

12 December 2020

Thiol and disulfide metabolites of the radiation protector and potential chemopreventive agent WR-2721 are linked to both its anti-cytotoxic and anti-mutagenic mechanisms of action

1 reference

12 December 2020

A comparison of radioprotection from three neutron sources and 60Co by WR-2721 and WR-151327

1 reference

12 December 2020

Dose and time relationships of the radioprotector WR-2721 on locomotor activity in mice

1 reference

12 December 2020

Interdependence of the radioprotective effects of human recombinant interleukin 1 alpha, tumor necrosis factor alpha, granulocyte colony-stimulating factor, and murine recombinant granulocyte-macrophage colony-stimulating factor

1 reference

12 December 2020

Comparison of in vivo murine intestinal radiation protection by E-prostaglandins

1 reference

12 December 2020

Final report on phase I trial of WR-2721 before protracted fractionated radiation therapy

1 reference

12 December 2020

Perspectives in radioprotection. Proceedings of the symposium. Bethesda, Maryland, 13-14 March 1987

1 reference

12 December 2020

Bone marrow cell protection and modification of drug toxicity by combination of protectors

1 reference

12 December 2020

Effects of ethiofos (WR-2721) and radiation on monkey visual discrimination performance

1 reference

12 December 2020

Radioprotection by metals: selenium

1 reference

12 December 2020

Clastogenic factors in the plasma of children exposed at Chernobyl

1 reference

12 December 2020

Thiol WR-1065 and disulphide WR-33278, two metabolites of the drug ethyol (WR-2721), protect DNA against fast neutron-induced strand breakage

1 reference

12 December 2020

Identifiers

DOI

10.1289/EHP.97105S61473

1 reference

3 August 2017

1 reference

3 August 2017

1 reference

PubMed ID

9467066