Interactions of human Cdc45 with the Mcm2-7 complex, the GINS complex, and DNA polymerases delta and epsilon during S phase. (Q34638233)

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1 January 2020

title

Interactions of human Cdc45 with the Mcm2-7 complex, the GINS complex, and DNA polymerases delta and epsilon during S phase (English)

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1 January 2020

4

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author name string

Christina Bauerschmidt

1

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1 January 2020

Sibyll Pollok

2

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1 January 2020

Elisabeth Kremmer

3

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1 January 2020

Frank Grosse

5

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1 January 2020

publication date

1 June 2007

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1 January 2020

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1 January 2020

volume

12

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1 January 2020

issue

6

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1 January 2020

page(s)

745-758

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Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication

1 January 2020

cites work

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Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase

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Cdc45-MCM-GINS, a new power player for DNA replication.

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Preventing re-replication of chromosomal DNA.

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Schizosaccharomyces pombe replication protein Cdc45/Sna41 requires Hsk1/Cdc7 and Rad4/Cut5 for chromatin binding

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Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast

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MCM2-7 complexes bind chromatin in a distributed pattern surrounding the origin recognition complex in Xenopus egg extracts.

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Eukaryotic MCM proteins: beyond replication initiation

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Distinct roles of DNA polymerases delta and epsilon at the replication fork in Xenopus egg extracts

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GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks

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Cdc45p assembles into a complex with Cdc46p/Mcm5p, is required for minichromosome maintenance, and is essential for chromosomal DNA replication

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Distinct roles for Sld3 and GINS during establishment and progression of eukaryotic DNA replication forks

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Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells

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Mimosine arrests proliferating human cells before onset of DNA replication in a dose-dependent manner.

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A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication

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Human CDC45 protein binds to minichromosome maintenance 7 protein and the p70 subunit of DNA polymerase alpha

21 January 2018

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Localisation of the DmCdc45 DNA replication factor in the mitotic cycle and during chorion gene amplification

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CDK- and Cdc45-dependent priming of the MCM complex on chromatin during S-phase in Xenopus egg extracts: possible activation of MCM helicase by association with Cdc45.

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Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis

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Central role for cdc45 in establishing an initiation complex of DNA replication in Xenopus egg extracts

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Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase

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A human homologue of the yeast replication protein Cdc21. Interactions with other Mcm proteins.

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A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication

21 January 2018

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Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication.

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Distinct pools of proliferating cell nuclear antigen associated to DNA replication sites interact with the p125 subunit of DNA polymerase delta or DNA ligase I.

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The human homolog of Saccharomyces cerevisiae CDC45

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Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression

21 January 2018

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The DNA polymerase activity of Pol epsilon holoenzyme is required for rapid and efficient chromosomal DNA replication in Xenopus egg extracts

21 January 2018

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Identification and cloning of two putative subunits of DNA polymerase epsilon in fission yeast

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GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast

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DNA synthesis at individual replication forks requires the essential initiation factor Cdc45p

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