Structures of Plasmodium vivax serine hydroxymethyltransferase: implications for ligand-binding specificity and functional control. (Q34639977)

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24 February 2020

title

Structures of Plasmodium vivax serine hydroxymethyltransferase: implications for ligand-binding specificity and functional control (English)

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Pimchai Chaiyen

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Yongyuth Yuthavong

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Somchart Maenpuen

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Penchit Chitnumsub

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Ubolsree Leartsakulpanich

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Ubolsree Leartsakulpanich

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Wanwipa Ittarat

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Aritsara Jaruwat

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Krittikar Noytanom

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author name string

Pinpunya Riangrungroj

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Worrapoj Oonanant

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Jarunee Vanichthanankul

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Phimonphan Chuankhayan

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publication date

22 November 2014

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Acta Crystallographica Section D: Biological Crystallography

24 February 2020

published in

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volume

70

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issue

Pt 12

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page(s)

3177-3186

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The structure of Plasmodium falciparum serine hydroxymethyltransferase reveals a novel redox switch that regulates its activities.

24 February 2020

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Distinct biochemical properties of human serine hydroxymethyltransferase compared with the Plasmodium enzyme: implications for selective inhibition

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Plasmodium serine hydroxymethyltransferase: indispensability and display of distinct localization

7 July 2018

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Plasmodium serine hydroxymethyltransferase as a potential anti-malarial target: inhibition studies using improved methods for enzyme production and assay

7 July 2018

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Structural and functional studies of Bacillus stearothermophilus serine hydroxymethyltransferase: the role of Asn(341), Tyr(60) and Phe(351) in tetrahydrofolate binding

7 July 2018

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Multidrug-resistant Plasmodium vivax associated with severe and fatal malaria: a prospective study in Papua, Indonesia

7 July 2018

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Structure determination and biochemical studies on Bacillus stearothermophilus E53Q serine hydroxymethyltransferase and its complexes provide insights on function and enzyme memory

7 July 2018

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Serine hydroxymethyltransferase revisited

7 July 2018

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7 July 2018

Plasmodium vivax malaria

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7 July 2018

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Use of non-crystallographic symmetry in protein structure refinement

7 July 2018

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Genetic and metabolic analysis of folate salvage in the human malaria parasite Plasmodium falciparum

7 July 2018

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Location of the pteroylpolyglutamate-binding site on rabbit cytosolic serine hydroxymethyltransferase

7 July 2018

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Cerebral involvement in benign tertian malaria.

7 July 2018

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Crystal structure of binary and ternary complexes of serine hydroxymethyltransferase from Bacillus stearothermophilus: insights into the catalytic mechanism

7 July 2018

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Structure of a murine cytoplasmic serine hydroxymethyltransferase quinonoid ternary complex: evidence for asymmetric obligate dimers

7 July 2018

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Crystal structure at 2.4 A resolution of E. coli serine hydroxymethyltransferase in complex with glycine substrate and 5-formyl tetrahydrofolate

7 July 2018

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7 July 2018

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Characterization, crystallization and preliminary X-ray analysis of bifunctional dihydrofolate reductase-thymidylate synthase from Plasmodium falciparum

7 July 2018

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Serine hydroxymethyl transferase from Streptococcus thermophilus and L-threonine aldolase from Escherichia coli as stereocomplementary biocatalysts for the synthesis of beta-hydroxy-alpha,omega-diamino acid derivatives

21 January 2018

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Enzymatic synthesis of diastereospecific carbacephem intermediates using serine hydroxymethyltransferase.

21 January 2018

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21 January 2018

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21 January 2018

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Serine hydroxymethyltransferase: role of glu75 and evidence that serine is cleaved by a retroaldol mechanism

21 January 2018

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21 January 2018

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10.1107/S1399004714023128

21 January 2018

Identifiers

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24 February 2020

PubMed publication ID

25478836

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