The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor (Q34647751)

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English	The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor	scientific article

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor (English)

1 reference

Europe PubMed Central

3 August 2017

author name string

Xiaoyun Wen

1

1 reference

Europe PubMed Central

3 August 2017

Karen M Duus

2

1 reference

Europe PubMed Central

3 August 2017

Thomas D Friedrich

3

1 reference

Europe PubMed Central

3 August 2017

Carlos M C de Noronha

4

1 reference

Europe PubMed Central

3 August 2017

language of work or name

0 references

publication date

9 July 2007

1 reference

Europe PubMed Central

3 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

3 August 2017

282

1 reference

Europe PubMed Central

3 August 2017

27046-27057

1 reference

Europe PubMed Central

3 August 2017

37

1 reference

Europe PubMed Central

3 August 2017

HIV-1 Vpr induces DNA double-strand breaks.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

HIV-1 Vpr increases viral expression by manipulation of the cell cycle: a mechanism for selection of Vpr in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Cooperative actions of HIV-1 Vpr and p53 modulate viral gene transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

The glucocorticoid receptor type II complex is a target of the HIV-1 vpr gene product

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Interaction of virion protein Vpr of human immunodeficiency virus type 1 with cellular transcription factor Sp1 and trans-activation of viral long terminal repeat

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

The human immunodeficiency virus type 1 Vpr transactivator: cooperation with promoter-bound activator domains and binding to TFIIB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

HIV transcriptional activation by the accessory protein, VPR, is mediated by the p300 co-activator

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Distinct effects in primary macrophages and lymphocytes of the human immunodeficiency virus type 1 accessory genes vpr, vpu, and nef: mutational analysis of a primary HIV-1 isolate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Characterization of HIV-1 vpr nuclear import: analysis of signals and pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Functional analysis of HIV-1 Vpr: identification of determinants essential for subcellular localization.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Nucleocytoplasmic shuttling by human immunodeficiency virus type 1 Vpr.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Identification of critical amino acid residues in human immunodeficiency virus type 1 IN required for efficient proviral DNA formation at steps prior to integration in dividing and nondividing cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Human immunodeficiency virus type 1 Vpr induces the degradation of the UNG and SMUG uracil-DNA glycosylases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

The fate of dsRNA in the nucleus: a p54(nrb)-containing complex mediates the nuclear retention of promiscuously A-to-I edited RNAs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Chromosomal localization and cDNA cloning of the genes (DDB1 and DDB2) for the p127 and p48 subunits of a human damage-specific DNA binding protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Cullin 4A associates with the UV-damaged DNA-binding protein DDB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Paramyxoviruses SV5 and HPIV2 assemble STAT protein ubiquitin ligase complexes from cellular components.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Cytoplasmic retention of HIV-1 regulatory protein Vpr by protein-protein interaction with a novel human cytoplasmic protein VprBP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

The paramyxovirus simian virus 5 V protein slows progression of the cell cycle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Simian virus 5 V protein acts as an adaptor, linking DDB1 to STAT2, to facilitate the ubiquitination of STAT1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Protein stability influences human immunodeficiency virus type 2 Vpr virion incorporation and cell cycle effect

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

An evolutionarily conserved function of proliferating cell nuclear antigen for Cdt1 degradation by the Cul4-Ddb1 ubiquitin ligase in response to DNA damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

PCNA is a cofactor for Cdt1 degradation by CUL4/DDB1-mediated N-terminal ubiquitination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Transactivation of Schizosaccharomyces pombe cdt2+ stimulates a Pcu4-Ddb1-CSN ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Involvement of CUL4 ubiquitin E3 ligases in regulating CDK inhibitors Dacapo/p27Kip1 and cyclin E degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703955200

21 January 2018

Identifiers

10.1074/JBC.M703955200

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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