Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyte-associated antigen 4 blockade and interleukin 2: a phase I/II study (Q34657668)

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English	Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyte-associated antigen 4 blockade and interleukin 2: a phase I/II study	scientific article

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9 January 2020

Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyte-associated antigen 4 blockade and interleukin 2: a phase I/II study (English)

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9 January 2020

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David E. Kleiner

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9 January 2020

Steven Rosenberg

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Steven A Rosenberg

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9 January 2020

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Peter Attia

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9 January 2020

Suzanne L. Topalian

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Suzanne L Topalian

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9 January 2020

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Ajay V Maker

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9 January 2020

Giao Q Phan

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9 January 2020

James C Yang

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9 January 2020

Richard M Sherry

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9 January 2020

Udai S Kammula

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9 January 2020

Richard E Royal

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9 January 2020

Leah R Haworth

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9 January 2020

Catherine Levy

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9 January 2020

Sharon A Mavroukakis

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9 January 2020

Michael Yellin

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9 January 2020

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21 October 2005

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9 January 2020

Annals of Surgical Oncology

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9 January 2020

12

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9 January 2020

12

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9 January 2020

1005-1016

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9 January 2020

Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473970

7 July 2018

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473970

7 July 2018

CTLA-4: new insights into its biological function and use in tumor immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473970

7 July 2018

Guidelines for the safe administration of high-dose interleukin-2.

1 reference

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7 July 2018

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473970

7 July 2018

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473970

7 July 2018

High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473970

7 July 2018

Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accomp

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473970

7 July 2018

CTLA-4-Mediated inhibition of early events of T cell proliferation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473970

7 July 2018

Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473970

7 July 2018

The emerging role of CTLA-4 as an immune attenuator

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473970

7 July 2018

Specific blockade of CTLA-4/B7 interactions results in exacerbated clinical and histologic disease in an actively-induced model of experimental allergic encephalomyelitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473970

7 July 2018

CD28/B7 system of T cell costimulation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473970

7 July 2018

CTLA-4 ligation blocks CD28-dependent T cell activation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473970

7 July 2018

CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473970

7 July 2018

Enhancement of antitumor immunity by CTLA-4 blockade

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473970

7 July 2018

Characterization of CTLA-4 structure and expression on human T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473970

7 July 2018

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

1 reference

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7 July 2018

CTLA-4 is a second receptor for the B cell activation antigen B7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473970

7 July 2018

Identification and distribution of the costimulatory receptor CD28 in the mouse

1 reference

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7 July 2018

Suppressive properties of human CD4+CD25+ regulatory T cells are dependent on CTLA-4 expression

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26 October 2018

Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade.

1 reference

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26 October 2018

CTLA-4 blockade enhances clinical disease and cytokine production during experimental allergic encephalomyelitis

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26 October 2018

A cell culture model for T lymphocyte clonal anergy

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Durability of complete responses in patients with metastatic cancer treated with high-dose interleukin-2: identification of the antigens mediating response

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https://pubmed.ncbi.nlm.nih.gov/16283570

12 December 2020

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10.1245/ASO.2005.03.536

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9 January 2020

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9 January 2020

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9 January 2020

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