The pathogenesis of diabetic retinopathy: old concepts and new questions (Q34658478)

3 August 2017

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title

The pathogenesis of diabetic retinopathy: old concepts and new questions (English)

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3 August 2017

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Cai J

1

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PubMed ID

12032713

3 August 2017

Boulton M

series ordinal

2

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3 August 2017

1 May 2002

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3 August 2017

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3 August 2017

16

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3 August 2017

3

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3 August 2017

242-260

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https://scigraph.springernature.com/pub.10.1038/sj.eye.6700133

3 August 2017

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21 January 2018

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21 January 2018

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Aldose reductase and the role of the polyol pathway in diabetic nephropathy

21 January 2018

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21 January 2018

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Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes

21 January 2018

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Retinal expression, regulation, and functional bioactivity of prostacyclin-stimulating factor

21 January 2018

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Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors

21 January 2018

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Cytochrome P450 2C is an EDHF synthase in coronary arteries

21 January 2018

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Bioassay of an endothelium-derived hyperpolarizing factor from bovine coronary arteries: role of a cytochrome P450 metabolite

21 January 2018

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Characterization of endothelium-derived hyperpolarizing factor as a cytochrome P450-derived arachidonic acid metabolite in mammals.

21 January 2018

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Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice

21 January 2018

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Endothelial dysfunction in diabetes.

21 January 2018

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Endothelin-1-induced vasoconstriction in humans. Reversal by calcium channel blockade but not by nitrovasodilators or endothelium-derived relaxing factor

21 January 2018

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Endothelin-1 as a mediator of endothelial cell-pericyte interactions in bovine brain capillaries.

21 January 2018

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Endothelin activates the dihydropyridine-sensitive, voltage-dependent Ca2+ channel in vascular smooth muscle

21 January 2018

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Cellular mechanism of action by a novel vasoconstrictor endothelin in cultured rat vascular smooth muscle cells.

21 January 2018

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Role of vasoactive factors in the pathogenesis of early changes in diabetic retinopathy

21 January 2018

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Losartan inhibits thromboxane A2-induced platelet aggregation and vascular constriction in spontaneously hypertensive rats.

21 January 2018

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The effect of cyclic GMP on rabbit corporal smooth muscle tone and its modulation by cyclo-oxygenase products.

21 January 2018

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Regional cerebral blood flow (rCBF) and cerebral vasoreactivity in patients with retinal ischaemic symptoms

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Aldose reductase inhibition prevents glucose-induced apoptosis in cultured bovine retinal microvascular pericytes

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Degenerated intramural pericytes (‘ghost cells’) in the retinal capillaries of diabetic rats

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Synthesis of flavonoids and their effects on aldose reductase and sorbitol accumulation in streptozotocin-induced diabetic rat tissues

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Polyol pathway activation and glutathione redox status in non-insulin-dependent diabetic patients

21 January 2018

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Amadorins: novel post-Amadori inhibitors of advanced glycation reactions.

21 January 2018

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Advanced glycation: an important pathological event in diabetic and age related ocular disease

21 January 2018

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Superoxide dismutase inhibits lipid peroxidation in micelles

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Catalase/superoxide dismutase (SOD) and catalase/paraoxonase (PON) ratios may implicate poor glycemic control

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Antioxidant enzymes and human diseases

21 January 2018

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Abnormalities of retinal metabolism in diabetes or experimental galactosemia. IV. Antioxidant defense system.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Endothelium-dependent vasoactive modulation in the ophthalmic circulation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Acute hypoxia and hypoxic exercise induce DNA strand breaks and oxidative DNA damage in humans

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Bax is increased in the retina of diabetic subjects and is associated with pericyte apoptosis in vivo and in vitro

21 January 2018

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Capillary lesions develop in retina rather than cerebral cortex in diabetes and experimental galactosemia.

21 January 2018

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Vascular lesions in diabetes are distributed non-uniformly within the retina

21 January 2018

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Histological and ultrastructural investigation of retinal microaneurysm development in diabetic patients

21 January 2018

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Fibronectin, laminin, vitronectin and their receptors at newly-formed capillaries in proliferative diabetic retinopathy

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Matrix metalloproteinase-2 is associated with tenascin-C in calcific aortic stenosis

21 January 2018

1 reference

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Increased prevalence of microthromboses in retinal capillaries of diabetic individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Presence of specific platelet-activating factor binding sites in the rat retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Effect of erythrocytes and prostacyclin production in the effect of fructose and sorbitol on platelet activation in human whole blood in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Prevention of leukostasis and vascular leakage in streptozotocin-induced diabetic retinopathy via intercellular adhesion molecule-1 inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Inhibition of activation of human peripheral blood eosinophils by Y-24180, an antagonist to platelet-activating factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Endothelial cell interactions with granulocytes: tethering and signaling molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Leukocyte-mediated endothelial cell injury and death in the diabetic retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Mechanics of stimulated neutrophils: cell stiffening induces retention in capillaries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Quantifying leukocyte dynamics and plugging in retinal microcirculation of streptozotosin-induced diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Advanced glycation end products increase retinal vascular endothelial growth factor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Alternative therapeutic principles in the prevention of microvascular and neuropathic complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Endothelial cell responses to hypoxia: initiation of a cascade of cellular interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Role of adhesion molecules in vascular regulation and damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Histopathology of diabetic retinopathy in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Echographic evaluation of a patient with diabetes and dense vitreous hemorrhage: an avulsed retinal vessel may mimic a tractional retinal detachment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Oxygen sensing and signaling: impact on the regulation of physiologically important genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Yeast flavohemoglobin is an ancient protein related to globins and a reductase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Hypoxia regulation of gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Hypoxia-inducible factor 1alpha and 1beta proteins share common signaling pathways in human prostate cancer cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

21 January 2018

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Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Vascular permeability/vascular endothelial growth factors: a potential role in the pathogenesis and treatment of vascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Role of vascular endothelial growth factor in the regulation of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting.

21 January 2018

1 reference

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The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

The 230 kDa mature form of KDR/Flk-1 (VEGF receptor-2) activates the PLC-gamma pathway and partially induces mitotic signals in NIH3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

The mechanism of phospholipase C-gamma1 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

VEGF localisation in diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Detection of vascular endothelial growth factor messenger RNA and vascular endothelial growth factor-like activity in proliferative diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Immunolocalisation of the VEGF receptors FLT-1, KDR, and FLT-4 in diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Vascular endothelial growth factor and severity of nonproliferative diabetic retinopathy mediate retinal hemodynamics in vivo: a potential role for vascular endothelial growth factor in the progression of nonproliferative diabetic retinopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Intravitreous injections of vascular endothelial growth factor produce retinal ischemia and microangiopathy in an adult primate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Vascular permeability factor/vascular endothelial cell growth factor-mediated permeability occurs through disorganization of endothelial junctional proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Inhibition of vascular endothelial growth factor prevents retinal ischemia-associated iris neovascularization in a nonhuman primate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Receptors and growth-promoting effects of insulin and insulinlike growth factors on cells from bovine retinal capillaries and aorta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

LY 294002, an inhibitor of phosphatidylinositol 3-kinase, inhibits GH-mediated expression of the IGF-I gene in rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Differences in survival-promoting effects and intracellular signaling properties of BDNF and IGF-1 in cultured cerebral cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Endogenous insulin-like growth factor (IGF) binding proteins cause IGF-1 resistance in cultured fibroblasts from a patient with short stature

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Vitreous levels of the insulin-like growth factors I and II, and the insulin-like growth factor binding proteins 2 and 3, increase in neovascular eye disease. Studies in nondiabetic and diabetic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Intravitreal growth factors in proliferative diabetic retinopathy: correlation with neovascular activity and glycaemic management

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Vitreous levels of IGF-I, IGF binding protein 1, and IGF binding protein 3 in proliferative diabetic retinopathy: a case-control study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Modulation of insulin-like growth factor (IGF) and IGF binding protein biosynthesis by hypoxia in cultured vascular endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Hypoxia stimulates insulin-like growth factor binding protein 1 (IGFBP-1) gene expression in HepG2 cells: a possible model for IGFBP-1 expression in fetal hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Production of IGF-I and IGF binding proteins by retinal cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Cultured bovine bone cells synthesize basic fibroblast growth factor and store it in their extracellular matrix.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Basic fibroblast growth factor binds to subendothelial extracellular matrix and is released by heparitinase and heparin-like molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Basic fibroblast growth factor is neither necessary nor sufficient for the development of retinal neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Fibroblast growth factor-2 (FGF-2) induces vascular endothelial growth factor (VEGF) expression in the endothelial cells of forming capillaries: an autocrine mechanism contributing to angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Signal transduction by the platelet-derived growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Oxygen tension regulates the expression of the platelet-derived growth factor-B chain gene in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Hypoxia-mediated induction of acidic/basic fibroblast growth factor and platelet-derived growth factor in mononuclear phagocytes stimulates growth of hypoxic endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Platelet-derived growth factor (PDGF) in oncogenesis: development of a vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Expression of hepatocyte growth factor and its receptor c-met in human leukemia-lymphoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Retinal pigment epithelial cells secrete and respond to hepatocyte growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Scatter factor induces blood vessel formation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Scatter factor promotes motility of human glioma and neuromicrovascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Hepatocyte growth factor/scatter factor (HGF/SF) induces vascular permeability factor (VPF/VEGF) expression by cultured keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

VEGF receptor subtypes KDR and FLT1 show different sensitivities to heparin and placenta growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Placenta growth factor stimulates MAP kinase and mitogenicity but not phospholipase C-gamma and migration of endothelial cells expressing Flt 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Placenta growth factor and vascular endothelial growth factor B and C expression in microvascular endothelial cells and pericytes. Implication in autocrine and paracrine regulation of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Growth factor signaling pathways in vascular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Angiopoietin-1 and its receptor Tie-2 participate in the regulation of capillary-like tubule formation and survival of endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Angiopoietin-1 induces sprouting angiogenesis in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Analysis of Tie receptor tyrosine kinase in haemopoietic progenitor and leukaemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Cell type-specific expression of angiopoietin-1 and angiopoietin-2 suggests a role in glioblastoma angiogenesis

21 January 2018

1 reference

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PEDF: a pigment epithelium-derived factor with potent neuronal differentiative activity

21 January 2018

1 reference

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PEDF: Raising both hopes and questions in controlling angiogenesis

21 January 2018

1 reference

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Pigment epithelium-derived factor: a potent inhibitor of angiogenesis

21 January 2018

1 reference

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Loss of the antiangiogenic pigment epithelium-derived factor in patients with angiogenic eye disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Prevention of ischemia-induced retinopathy by the natural ocular antiangiogenic agent pigment epithelium-derived factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Pigment epithelium-derived factor inhibits retinal and choroidal neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

Ocular vascular endothelial growth factor levels in diabetic rats are elevated before observable retinal proliferative changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

The role of oxidative stress in diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Diabetes downregulates GLUT1 expression in the retina and its microvessels but not in the cerebral cortex or its microvessels

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Overview of studies on metabolic and vascular regulatory changes in early diabetic retinopathy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Central retinal artery innervation. Absence of adrenergic innervation to the intraocular branches

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in man

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Nitric oxide regulates basal systemic and pulmonary vascular resistance in healthy humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Mediators of leukocyte adhesion in rat mesenteric venules elicited by inhibition of nitric oxide synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Nitric oxide and prostacyclin. Divergence of inhibitory effects on monocyte chemotaxis and adhesion to endothelium in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Nitrovasodilators inhibit thrombin-induced platelet-activating factor synthesis in human endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Interaction of transmural pressure and shear stress in the transport of albumin across the rabbit aortic wall

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Lactacystin stimulates arachidonic acid metabolism in rat liver cells: effects of cell density on arachidonic acid release, PGI2 production and cyclooxygenase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Prostaglandin E2-induced sensitization of bradykinin-evoked responses in rat dorsal root ganglion neurons is mediated by cAMP-dependent protein kinase A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

The mechanism of thrombin-induced prostacyclin synthesis in human endothelial cells with reference to the gene transcription of prostacyclin-related enzymes and Ca2+ kinetics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Extracellular K(+)-induced hyperpolarizations and dilatations of rat coronary and cerebral arteries involve inward rectifier K(+) channels

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Gap junctional communication underpins EDHF-type relaxations evoked by ACh in the rat hepatic artery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Constriction of mouse hepatic venules and sinusoids by endothelins through ETB receptor subtype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Activation of phospholipase A2 by endothelin in cultured vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Role of protein kinase C alpha and mitogen-activated protein kinases in endothelin-1-stimulation of cytosolic phospholipase A2 in iris sphincter smooth muscle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Eicosanoid profile in cultured human pulmonary artery smooth muscle cells treated with IL-1 beta and TNF alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Diabeteslike proliferative retinal changes in galactose-fed dogs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

In vitro inhibition of glucose phosphorylation by an aldose-reductase inhibitor (Tolrestat) in some non-insulin-sensitive rabbit tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

The development of electroretinogram abnormalities and the possible role of polyol pathway activity in diabetic hyperglycemia and galactosemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Effects of polyol-pathway inhibition and dietary myo-inositol on glomerular hemodynamic function in experimental diabetes mellitus in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Alpha-lipoic acid: effect on glucose uptake, sorbitol pathway, and energy metabolism in experimental diabetic neuropathy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Age-dependent accumulation of N epsilon-(carboxymethyl)lysine and N epsilon-(carboxymethyl)hydroxylysine in human skin collagen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

The glutathione levels are reduced in Goto-Kakizaki rat retina, but are not influenced by aminoguanidine treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

F(2) isoprostanes, potential specific markers of oxidative damage in human retina

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Oxidative DNA damage in diabetes mellitus: its association with diabetic complications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Glycoprotein deposition in vascular walls of diabetic retinopathy. A histopathological and immunohistochemical study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Diabetic preretinal membranes. An immunohistochemical study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Epiretinal membrane of proliferative diabetic retinopathy: an immunohistochemical study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Phenotypic expression of collagen types in mesangial matrix of diabetic and nondiabetic rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Basement membrane and growth factor gene expression in normal and diabetic human retinas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

d-Alpha-tocopherol prevents the hyperglycemia induced activation of diacylglycerol (DAG)-protein kinase C (PKC) pathway in vascular smooth muscle cell by an increase of DAG kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Activation of human neutrophil by cytokine-activated endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Effect of WEB 2086-BS, an antagonist of platelet-activating factor receptors, on retinal vascularity in diabetic rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Significance of platelet-derived microparticles and activated platelets in diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Enhanced Shear-induced von Willebrand Factor Binding to Platelets in Acute Myocardial Infarction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Decreased degradation of collagen and fibronectin following exposure of proximal cells to glucose

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Effect of camonagrel, a selective thromboxane synthase inhibitor, on retinal vascularization in experimental diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Phorbol ester stimulates PAF synthesisvia the activation of protein kinase C in rat leukocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Exogenous nitric oxide increases neutrophil adhesion to cultured human endothelial monolayers through a protein kinase G dependent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Inhibition of platelet-activating factor synthesis in human neutrophils and platelets by propionyl-L-carnitine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

The microcirculation and inflammation: modulation of leukocyte-endothelial cell adhesion.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Modulation of endothelial cell expression of intercellular adhesion molecule 1 by protein kinase C activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Increased expression of neutrophil and monocyte adhesion molecules LFA-1 and Mac-1 and their ligand ICAM-1 and VLA-4 throughout the acute phase of myocardial infarction: possible implications for leukocyte aggregation and microvascular plugging

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Cystoid macular degeneration in experimental branch retinal vein occlusion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Basic Fibroblast Growth Factor Levels in the Vitreous of Patients With Proliferative Diabetic Retinopathy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Retinal vascularization in health and disease: Proctor Award Lecture of the Association for Research in Ophthalmology.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Foveal haemorrhages in diabetic retinopathy. Clinical characteristics and visual outcome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

VEGF-induced activation of phosphoinositide 3-kinase is dependent on focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Vascular endothelial growth factor induces expression of connective tissue growth factor via KDR, Flt1, and phosphatidylinositol 3-kinase-akt-dependent pathways in retinal vascular cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Upregulation of retinal vascular endothelial growth factor mRNAs in spontaneously diabetic rats without ophthalmoscopic retinopathy. A possible participation of advanced glycation end products in the development of the early phase of diabetic retino

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Expression of the VEGF gene family during retinal vaso-obliteration and hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Hypoxia promotes oxidative base modifications in the pulmonary artery endothelial cell VEGF gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Retinal Blood Flow Alterations During Progression of Diabetic Retinopathy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Recovery from retinopathy in a case of diabetes with Simmonds' disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Essential role of growth hormone in ischemia-induced retinal neovascularization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

A two-year follow-up study of serum insulinlike growth factor-I in diabetics with retinopathy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Serum IGF-1 concentration in diabetic retinopathy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Insulin-like growth factor I acts as an angiogenic agent in rabbit cornea and retina: comparative studies with basic fibroblast growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

IGF-I of serum and vitreous fluid in patients with diabetic proliferative retinopathy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Stimulatory effects of insulin and insulin-like growth factor I on migration and tube formation by vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Insulin-like growth factor-I is necessary for neural stem cell proliferation and demonstrates distinct actions of epidermal growth factor and fibroblast growth factor-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Insulin-like growth factor: receptor and binding proteins in human retinal endothelial cell cultures of diabetic and non-diabetic origin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Basic fibroblast growth factor is released from endothelial extracellular matrix in a biologically active form

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Basic fibroblast growth factor upregulates the expression of vascular endothelial growth factor in vascular smooth muscle cells. Synergistic interaction with hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Increased levels of platelet-derived growth factor in vitreous fluid of patients with proliferative diabetic retinopathy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Migratory and proliferative effect of platelet-derived growth factor in rabbit retinal endothelial cells: evidence of an autocrine pathway of platelet-derived growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Rat brain capillary endothelial cells express functional PDGF B-type receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Potential role of an endothelium-specific growth factor, hepatocyte growth factor, on endothelial damage in diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: the case for paracrine amplification of angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Heterodimers of placenta growth factor/vascular endothelial growth factor. Endothelial activity, tumor cell expression, and high affinity binding to Flk-1/KDR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Expression of placenta growth factor (PIGF) in ischaemic retinal diseases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Hypoxia and vascular endothelial growth factor selectively up-regulate angiopoietin-2 in bovine microvascular endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EYE.6700133

7 January 2021

Identifiers

DOI

10.1038/SJ.EYE.6700133

1 reference

PubMed ID

12032713

Dimensions Publication ID

3 August 2017

0 references

1 reference

PubMed ID

12032713