Replicative senescence of hematopoietic stem cells during serial transplantation: does telomere shortening play a role? (Q34658505)

3 August 2017

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title

Replicative senescence of hematopoietic stem cells during serial transplantation: does telomere shortening play a role? (English)

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3 August 2017

Richard C Allsopp

1

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3 August 2017

Irving L Weissman

series ordinal

2

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3 August 2017

language of work or name

English

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publication date

1 May 2002

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3 August 2017

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3 August 2017

21

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3 August 2017

21

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3 August 2017

3270-3273

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205314

3 August 2017

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cites work

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Loss of proliferative capacity in immunohemopoietic stem cells caused by serial transplantation rather than aging

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Telomere shortening accompanies increased cell cycle activity during serial transplantation of hematopoietic stem cells

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7 January 2021

Telomere length predicts replicative capacity of human fibroblasts

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Mechanism of telomerase induction during T cell activation

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Telomerase activity in normal and malignant hematopoietic cells

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Telomere length and replicative aging in human vascular tissues

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In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells

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Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow

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Replicative senescence in the immune system: impact of the Hayflick limit on T-cell function in the elderly

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Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

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The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

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7 January 2021

Mammalian telomeres end in a large duplex loop

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7 January 2021

Subtelomeric as well as telomeric sequences are lost from chromosomes in proliferating B lymphocytes

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Creation of human tumour cells with defined genetic elements

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Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes

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Telomeres shorten during ageing of human fibroblasts

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Telomere reduction in human colorectal carcinoma and with ageing

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The serial cultivation of human diploid cell strains

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7 January 2021

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

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Immortalization of human CD8+ T cell clones by ectopic expression of telomerase reverse transcriptase

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Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype

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Specific association of human telomerase activity with immortal cells and cancer

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Hypervariable ultra-long telomeres in mice

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Telomere reduction and telomerase inactivation during neuronal cell differentiation

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Telomere end-replication problem and cell aging

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Telomerase and DNA end replication: no longer a lagging strand problem?

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Telomerase activity in germline and embryonic cells of Xenopus.

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Telomeres and their control

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7 January 2021

Telomerase activity in hematopoietic cells is associated with self-renewal potential

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7 January 2021

Severe growth defect in mouse cells lacking the telomerase RNA component.

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7 January 2021

In vivo telomere dynamics of human hematopoietic stem cells

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7 January 2021

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions

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7 January 2021

Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes

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7 January 2021

Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential.

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7 January 2021

TLC1: template RNA component of Saccharomyces cerevisiae telomerase

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7 January 2021

Gradual phenotypic conversion associated with immortalization of cultured human mammary epithelial cells

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7 January 2021

The human papillomavirus type 16 E6 and E7 oncoproteins dissociate cellular telomerase activity from the maintenance of telomere length

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7 January 2021

Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205314

7 January 2021

Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205314

7 January 2021

Mild Hyperoxia Shortens Telomeres and Inhibits Proliferation of Fibroblasts: A Model for Senescence?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205314

7 January 2021

Normal human chromosomes have long G-rich telomeric overhangs at one end

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205314

7 January 2021

Human endothelial cell life extension by telomerase expression

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205314

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205314

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Dimensions Publication ID

3 August 2017

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1 reference