Inosine to increase serum and cerebrospinal fluid urate in Parkinson disease: a randomized clinical trial (Q34658560)

3 August 2017

title

Inosine to increase serum and cerebrospinal fluid urate in Parkinson disease: a randomized clinical trial (English)

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3 August 2017

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Eric A Macklin

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Christopher G. Goetz

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object named as

Christopher G Goetz

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Michael A Schwarzschild

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Michael A Schwarzschild

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Alberto Ascherio

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Joseph H Friedman

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Merit E Cudkowicz

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M Flint Beal

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Ira Shoulson

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David Oakes

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author name string

Parkinson Study Group SURE-PD Investigators

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Gary C Curhan

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Joshua M Hare

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D Craig Hooper

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Karl D Kieburtz

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Alice Rudolph

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Marsha K Tennis

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Alberto J Espay

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Maureen Gartner

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Albert Hung

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Grace Bwala

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Richard Lenehan

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Elmyra Encarnacion

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Melissa Ainslie

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Richard Castillo

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Daniel Togasaki

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Gina Barles

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Lisa Niles

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Julie H Carter

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Megan Murray

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Jeana Jaglin

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Anwar Ahmed

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David S Russell

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Candace Cotto

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John L Goudreau

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Doozie Russell

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Sotirios Andreas Parashos

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Patricia Ede

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Marie H Saint-Hilaire

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Cathi-Ann Thomas

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Raymond James

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Mark A Stacy

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Julia Johnson

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Lisa Gauger

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J Antonelle de Marcaida

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Sheila Thurlow

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Stuart H Isaacson

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Lisbeth Carvajal

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Jayaraman Rao

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Maureen Cook

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Charlise Hope-Porche

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Lauren McClurg

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Daniela L Grasso

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Robert Logan

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Constance Orme

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Tori Ross

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Alicia F D Brocht

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Radu Constantinescu

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Saloni Sharma

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Charles Venuto

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Joseph Weber

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Ken Eaton

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3 August 2017

language of work or name

English

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publication date

1 February 2014

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3 August 2017

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volume

71

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issue

2

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3 August 2017

page(s)

141-150

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Potential role of uric acid in metabolic syndrome, hypertension, kidney injury, and cardiovascular diseases: is it time for reappraisal?

3 August 2017

cites work

1 reference

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Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegeneration

7 July 2018

1 reference

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Design innovations and baseline findings in a long-term Parkinson's trial: the National Institute of Neurological Disorders and Stroke Exploratory Trials in Parkinson's Disease Long-Term Study-1.

7 July 2018

1 reference

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Urate and its transgenic depletion modulate neuronal vulnerability in a cellular model of Parkinson's disease

7 July 2018

1 reference

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Boosting endogenous neuroprotection in multiple sclerosis: the ASsociation of Inosine and Interferon beta in relapsing- remitting Multiple Sclerosis (ASIIMS) trial

7 July 2018

1 reference

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Urate as a predictor of the rate of clinical decline in Parkinson disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940333

The treatment of multiple sclerosis with inosine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940333

Serum urate as a predictor of clinical and radiographic progression in Parkinson disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940333

A comparison of the mini mental state exam to the Montreal cognitive assessment in identifying cognitive deficits in Parkinson's disease.

7 July 2018

1 reference

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Plasma urate and risk of Parkinson's disease

7 July 2018

1 reference

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Depression rating scales in Parkinson's disease: critique and recommendations

7 July 2018

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Therapeutic value of serum uric acid levels increasing in the treatment of multiple sclerosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940333

Optimizing the ongoing search for new treatments for Parkinson disease: using futility designs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940333

Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940333

Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940333

Serum uric acid and cholesterol in achievement behavior and motivation. I. The relationship to ability, grades, test performance, and motivation.

7 July 2018

1 reference

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Uric acid-iron ion complexes. A new aspect of the antioxidant functions of uric acid.

7 July 2018

1 reference

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Neuroprotection by urate on 6-OHDA-lesioned rat model of Parkinson's disease: linking to Akt/GSK3β signaling pathway

7 July 2018

1 reference

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Modulation of serum uric acid levels by inosine in patients with multiple sclerosis does not affect blood pressure.

26 October 2018

1 reference

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Measuring cognition in a geriatric outpatient clinic: Rasch analysis of the Montreal Cognitive Assessment

26 October 2018

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Mixed lineage kinase inhibitor CEP-1347 fails to delay disability in early Parkinson disease

26 October 2018

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A randomized, double-blind, futility clinical trial of creatine and minocycline in early Parkinson disease

26 October 2018

1 reference

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Test-retest reliability of the unified Parkinson's disease rating scale in patients with early Parkinson's disease: results from a multicenter clinical trial

26 October 2018

1 reference

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Effect of inosine on the plasma concentration of uridine and purine bases

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940333

Inactivation of peroxynitrite in multiple sclerosis patients after oral administration of inosine may suggest possible approaches to therapy of the disease

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940333

Observations on serum uric acid levels and the risk of idiopathic Parkinson's disease

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940333

Serum uric acid levels and the risk of Parkinson disease

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940333

Uric acid and cardiovascular risk

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24366103

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366103

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Uric acid nephrolithiasis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24366103

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1001/JAMANEUROL.2013.5528

1 reference

3 August 2017

1 reference

3 August 2017

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