Delivery of inhibitor of growth 4 (ING4) gene significantly inhibits proliferation and invasion and promotes apoptosis of human osteosarcoma cells. (Q34660653)

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English	Delivery of inhibitor of growth 4 (ING4) gene significantly inhibits proliferation and invasion and promotes apoptosis of human osteosarcoma cells.	scientific article

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24 February 2020

Delivery of inhibitor of growth 4 (ING4) gene significantly inhibits proliferation and invasion and promotes apoptosis of human osteosarcoma cells (English)

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24 February 2020

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Mei Li

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24 February 2020

Ye Zhu

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24 February 2020

Hongbin Zhang

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Lihua Li

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Peng He

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Hong Xia

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Yu Zhang

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9 December 2014

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9 December 2014

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https://scigraph.springernature.com/pub.10.1038/srep07380

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Stem cells loaded with nanoparticles as a drug carrier for in vivo breast cancer therapy

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Involvement of extracellular signal-regulated kinase (ERK1/2)-p53-p21 axis in mediating neural stem/progenitor cell cycle arrest in co-morbid HIV-drug abuse exposure.

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Tumor suppressor ING4 overexpression contributes to proliferation and invasion inhibition in gastric carcinoma by suppressing the NF-κB signaling pathway

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The ING4 Binding with p53 and Induced p53 Acetylation were Attenuated by Human Papillomavirus 16 E6.

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7 July 2018

ING4 regulates a secretory phenotype in primary fibroblasts with dual effects on cell proliferation and tumor growth

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7 July 2018

Negative regulation of NF-κB by the ING4 tumor suppressor in breast cancer

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Cell cycle regulation by the intrinsically disordered proteins p21 and p27.

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7 July 2018

Effect of the tumor suppressor gene ING4 on the proliferation of MCF-7 human breast cancer cells

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7 July 2018

Enhanced tumor suppression by an ING4/IL-24 bicistronic adenovirus-mediated gene cotransfer in human non-small cell lung cancer cells

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Targeted therapies in bone sarcomas: current approach and future directions

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Evolutionary selection of new breast cancer cell-targeting peptides and phages with the cell-targeting peptides fully displayed on the major coat and their effects on actin dynamics during cell internalization.

1 reference

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7 July 2018

Down-regulation of ING4 is associated with initiation and progression of lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260466

7 July 2018

Targeted therapies in bone sarcomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260466

7 July 2018

Osteogenic sarcoma (osteosarcoma) in the elderly: tumor delineation and predisposing conditions.

1 reference

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7 July 2018

The ING gene family in the regulation of cell growth and tumorigenesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260466

7 July 2018

The inhibitor of growth (ING) gene family: potential role in cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260466

7 July 2018

Role of ING4 in human melanoma cell migration, invasion and patient survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260466

7 July 2018

After a decade of study-ING, a PHD for a versatile family of proteins

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7 July 2018

Inhibitor of growth 4 suppresses cell spreading and cell migration by interacting with a novel binding partner, liprin alpha1.

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7 July 2018

Osteosarcoma (osteogenic sarcoma).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260466

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The candidate tumor suppressor ING4 represses activation of the hypoxia inducible factor (HIF).

1 reference

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7 July 2018

Nuclear localization signal of ING4 plays a key role in its binding to p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260466

7 July 2018

G1 cell-cycle control and cancer

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Biological functions of the ING family tumor suppressors

1 reference

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NF-kappaB: tumor promoter or suppressor?

1 reference

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The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis

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p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity

1 reference

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1 reference

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ING4 is negatively correlated with microvessel density in colon cancer

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21 January 2018

Expression of tumor suppressor gene ING4 in ovarian carcinoma is correlated with microvessel density

1 reference

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21 January 2018

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1 reference

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21 January 2018

Loss of inhibitor of growth (ING-4) is implicated in the pathogenesis and progression of human astrocytomas.

1 reference

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1 reference

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Adenovirus-mediated ING4 Gene Transfer in Osteosarcoma Suppresses Tumor Growth via Induction of Apoptosis and Inhibition of Tumor Angiogenesis

1 reference

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10.1038/SREP07380

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24 February 2020

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24 February 2020

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24 February 2020

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