Treatment of geographic atrophy by the topical administration of OT-551: results of a phase II clinical trial (Q34662112)

3 August 2017

Treatment of geographic atrophy by the topical administration of OT-551: results of a phase II clinical trial (English)

1 reference

3 August 2017

phase II clinical trial

0 references

1 reference

8

Emily Y Chew

1 reference

3 August 2017

7

Catherine Cukras

1 reference

3 August 2017

Wai T Wong

1

1 reference

3 August 2017

Waynekid Kam

2

1 reference

3 August 2017

Denise Cunningham

3

1 reference

3 August 2017

Molly Harrington

4

1 reference

3 August 2017

Keri Hammel

5

1 reference

3 August 2017

Catherine B Meyerle

6

1 reference

3 August 2017

Srinivas R Sadda

9

1 reference

3 August 2017

Frederick L Ferris

10

1 reference

3 August 2017

language of work or name

English

0 references

publication date

23 June 2010

1 reference

Investigative Ophthalmology Visual Science

3 August 2017

1 reference

3 August 2017

51

1 reference

3 August 2017

12

1 reference

3 August 2017

6131-6139

1 reference

Natural history of drusenoid pigment epithelial detachment in age-related macular degeneration: Age-Related Eye Disease Study Report No. 28.

3 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Selective retina therapy (SRT) in patients with geographic atrophy due to age-related macular degeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Change in area of geographic atrophy in the Age-Related Eye Disease Study: AREDS report number 26.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Comparison of fundus autofluorescence of age-related macular degeneration between a fundus camera and a confocal scanning laser ophthalmoscope

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Chronic cigarette smoke causes oxidative damage and apoptosis to retinal pigmented epithelial cells in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

The epidemiology of progression of pure geographic atrophy: the Beaver Dam Eye Study

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

High-resolution spectral domain-OCT imaging in geographic atrophy associated with age-related macular degeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Low luminance visual dysfunction as a predictor of subsequent visual acuity loss from geographic atrophy in age-related macular degeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Oxidative damage-induced inflammation initiates age-related macular degeneration.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

OT-674 suppresses photooxidative processes initiated by an RPE lipofuscin fluorophore.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Retinal precursors and the development of geographic atrophy in age-related macular degeneration.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

New therapeutic targets in atrophic age-related macular degeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Designing clinical trials for age-related geographic atrophy of the macula: enrollment data from the geographic atrophy natural history study

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

The long-term natural history of geographic atrophy from age-related macular degeneration: enlargement of atrophy and implications for interventional clinical trials

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Issues in quantifying atrophic macular disease using retinal autofluorescence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Modelling the natural history of geographic atrophy in patients with age-related macular degeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Neuroprotective effects of TEMPOL in central and peripheral nervous system models of Parkinson's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Current concepts in the pathogenesis of age-related macular degeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Aging: a theory based on free radical and radiation chemistry

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

A2E-epoxides damage DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Drusen proteome analysis: an approach to the etiology of age-related macular degeneration.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Analysis of digital scanning laser ophthalmoscopy fundus autofluorescence images of geographic atrophy in advanced age-related macular degeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. 9

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Cellular sites of H2O2-induced damage and their protection by nitroxides

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

The role of oxidative stress in the pathogenesis of age-related macular degeneration.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Improvement of visual acuity over time in patients with bilateral geographic atrophy from age-related macular degeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Fixation patterns and reading rates in eyes with central scotomas from advanced atrophic age-related macular degeneration and Stargardt disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Scanning laser ophthalmoscopic analysis of the pattern of visual loss in age-related geographic atrophy of the macula

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Nitroxides block DNA scission and protect cells from oxidative damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Risk factors for age-related macular degeneration: Pooled findings from three continents.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055748

Fifteen-Year Cumulative Incidence of Age-Related Macular Degeneration

26 October 2018

1 reference

12 December 2020

Protective effect of TEMPOL derivatives against light-induced retinal damage in rats

1 reference

12 December 2020

Asymptomatic peripapillary subretinal hemorrhage: a study of 10 cases

1 reference

12 December 2020

Evolution of geographic atrophy of the retinal pigment epithelium

1 reference

12 December 2020

Risk factors of age-related maculopathy in a population 70 years of age or older

1 reference

12 December 2020

N(epsilon)(carboxymethyl)lysin and the AGE receptor RAGE colocalize in age-related macular degeneration

1 reference

12 December 2020

Enlargement of atrophy and visual acuity loss in the geographic atrophy form of age-related macular degeneration

1 reference

12 December 2020

Identifiers

DOI

10.1167/IOVS.10-5637

1 reference

3 August 2017

1 reference

3 August 2017

1 reference