Induction of fetal globin in beta-thalassemia: Cellular obstacles and molecular progress (Q34668049)

3 August 2017

Induction of fetal globin in beta-thalassemia: Cellular obstacles and molecular progress (English)

1 reference

3 August 2017

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Susan P Perrine

1

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3 August 2017

Serguei A Castaneda

2

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3 August 2017

Michael S Boosalis

3

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3 August 2017

Gary L White

4

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3 August 2017

Brandon M Jones

5

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3 August 2017

Regine Bohacek

6

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3 August 2017

language of work or name

English

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publication date

1 January 2005

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Annals of the New York Academy of Sciences

3 August 2017

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3 August 2017

1054

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3 August 2017

257-265

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Butyrate increases the efficiency of translation of gamma-globin mRNA.

3 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4261694

Induction of human gamma globin gene expression by histone deacetylase inhibitors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4261694

Induction of fetal hemoglobin by propionic and butyric acid derivatives: correlations between chemical structure and potency of Hb F induction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4261694

Short-chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4261694

Pharmacologic modulation of fetal hemoglobin.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4261694

Short-chain fatty acid derivatives stimulate cell proliferation and induce STAT-5 activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4261694

Sustained induction of fetal hemoglobin by pulse butyrate therapy in sickle cell disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4261694

Butyrate-induced G1 arrest results from p21-independent disruption of retinoblastoma protein-mediated signals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4261694

The tumorigenicity of 5-azacytidine in the male Fischer rat.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4261694

Activation of a chicken embryonic globin gene in adult erythroid cells by 5-azacytidine and sodium butyrate

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4261694

5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4261694

Treatment of mice with 5-azacytidine efficiently activates silent retroviral genomes in different tissues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4261694

The Importance of the Genetic Picture and Globin Synthesis in Determining the Clinical and Haematological Features of Thalassaemia Intermedia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4261694

Hydroxamide derivatives of short-chain fatty acids are potent inducers of human fetal globin gene expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4261694

The importance of erythroid expansion in determining the extent of apoptosis in erythroid precursors in patients with beta-thalassemia major.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4261694

The changing profile of homozygous beta-thalassemia: demography, ethnicity, and age distribution of current North American patients and changes in two decades.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4261694

Administration of high doses of recombinant human erythropoietin to patients with beta-thalassemia intermedia: a preliminary trial

26 October 2018

1 reference

12 December 2020

Accelerated programmed cell death (apoptosis) in erythroid precursors of patients with severe beta-thalassemia (Cooley's anemia)

1 reference

12 December 2020

Alterations in protein-DNA interactions in the gamma-globin gene promoter in response to butyrate therapy

1 reference

12 December 2020

Oral sodium phenylbutyrate therapy in homozygous beta thalassemia: a clinical trial

1 reference

12 December 2020

Pharmacologic treatment of thalassemia intermedia with hydroxyurea

1 reference

12 December 2020

Serum erythropoietin and erythropoiesis in high- and low-fetal hemoglobin beta-thalassemia intermedia patients

1 reference

12 December 2020

DNA methylation and cancer

1 reference

12 December 2020

On the induction of fetal hemoglobin by butyrates: in vivo and in vitro studies with sodium butyrate and comparison of combination treatments with 5-AzaC and AraC

1 reference

12 December 2020

Recombinant human erythropoietin trial in thalassemia intermedia

1 reference

12 December 2020

Sustained increase in haemoglobin and RBC following long-term administration of recombinant human erythropoietin to patients with homozygous beta-thalassaemia

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12 December 2020

Hydroxyurea increases hemoglobin F levels and improves the effectiveness of erythropoiesis in beta-thalassemia/hemoglobin E disease

1 reference

12 December 2020

5-Azacytidine treatment in a beta (0)-thalassaemic patient unable to be transfused due to multiple alloantibodies

1 reference

12 December 2020

Brief report: treatment with azacitidine of patients with end-stage beta-thalassemia

1 reference

12 December 2020

Increased fetal hemoglobin production in patients receiving valproic acid for epilepsy

1 reference

12 December 2020

Stimulation of fetal hemoglobin production by short chain fatty acids

1 reference

12 December 2020

2-deoxy 5-azacytidine and fetal hemoglobin induction in sickle cell anemia

1 reference

12 December 2020

5-Azacytidine Selectively Increases γ-Globin Synthesis in a Patient with β+Thalassemia

1 reference

12 December 2020

A short-term trial of butyrate to stimulate fetal-globin-gene expression in the beta-globin disorders

1 reference

12 December 2020

Identifiers

DOI

10.1196/ANNALS.1345.033

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3 August 2017

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3 August 2017

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