Exploiting cross-reactivity to neutralize two different scorpion venoms with one single chain antibody fragment (Q34675779)

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18 January 2020

title

Exploiting cross-reactivity to neutralize two different scorpion venoms with one single chain antibody fragment (English)

1 reference

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18 January 2020

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1 reference

5

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18 January 2020

Lourival Possani Postay

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object named as

Lourival D Possani

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18 January 2020

7

Baltazar Becerril

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18 January 2020

1

Lidia Riaño-Umbarila

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Timoteo Olamendi-Portugal

18 January 2020

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object named as

Timoteo Olamendi-Portugal

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18 January 2020

Citlalli Morelos-Juárez

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object named as

Citlalli Morelos-Juárez

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18 January 2020

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author name string

Gabriel Contreras-Ferrat

2

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18 January 2020

language of work or name

English

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publication date

14 December 2010

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18 January 2020

number of pages

9

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Journal of Biological Chemistry

inferred from page(s)

published in

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18 January 2020

volume

286

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18 January 2020

issue

8

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18 January 2020

page(s)

6143-6151

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Heterologous expressed toxic and non-toxic peptide variants of toxin CssII are capable to produce neutralizing antibodies against the venom of the scorpion Centruroides suffusus suffusus.

18 January 2020

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Resurgent current and voltage sensor trapping enhanced activation by a beta-scorpion toxin solely in Nav1.6 channel. Significance in mice Purkinje neurons.

7 July 2018

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7 July 2018

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Overview of scorpion toxins specific for Na+ channels and related peptides: biodiversity, structure-function relationships and evolution

7 July 2018

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A strategy for the generation of specific human antibodies by directed evolution and phage display. An example of a single-chain antibody fragment that neutralizes a major component of scorpion venom

7 July 2018

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Fine tuning of the specificity of an anti-progesterone antibody by first and second sphere residue engineering

7 July 2018

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Directed evolution, phage display and combination of evolved mutants: a strategy to recover the neutralization properties of the scFv version of BCF2 a neutralizing monoclonal antibody specific to scorpion toxin Cn2.

7 July 2018

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Directed evolution of an anti-carcinoembryonic antigen scFv with a 4-day monovalent dissociation half-time at 37 degrees C.

7 July 2018

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Engineering of a recombinant Fab from a neutralizing IgG directed against scorpion neurotoxin AahI, and functional evaluation versus other antibody fragments

7 July 2018

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Antivenom treatment in arachnidism

7 July 2018

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Design and evaluation of a diabody to improve protection against a potent scorpion neurotoxin.

7 July 2018

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Further improvement of broad specificity hapten recognition with protein engineering

7 July 2018

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Biophysical properties of human antibody variable domains

7 July 2018

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7 July 2018

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A single H:CDR3 residue in the anti-digoxin antibody 26-10 modulates specificity for C16-substituted digoxin analogs

7 July 2018

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7 July 2018

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Quantitative analysis of the effect of the mutation frequency on the affinity maturation of single chain Fv antibodies

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Amino acid sequence and immunological characterization with monoclonal antibodies of two toxins from the venom of the scorpion Centruroides noxius Hoffmann

7 July 2018

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Somatic mutations can lead to a loss of superantigenic and polyreactive binding

7 July 2018

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Directed evolution for the development of conformation-specific affinity reagents using yeast display

21 January 2018

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Isolation and characterization of a novel toxin from the venom of the scorpion Centruroides limpidus limpidus Karsch

21 January 2018

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Construction and functional evaluation of a single-chain antibody fragment that neutralizes toxin AahI from the venom of the scorpion Androctonus australis hector.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.189175

Bacterial expression, purification and functional characterization of a recombinant chimeric Fab derived from murine mAb BCF2 that neutralizes the venom of the scorpion Centruroides noxius hoffmann

21 January 2018

1 reference

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Antibody BCF2 against scorpion toxin Cn2 from Centuroides noxius Hoffmann: primary structure and three-dimensional model as free Fv fragment and complexed with its antigen.

21 January 2018

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Identification of potent nanobodies to neutralize the most poisonous polypeptide from scorpion venom

26 October 2018

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A bispecific nanobody to provide full protection against lethal scorpion envenoming

21 January 2018

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Isolation and characterization of two toxins from the Mexican scorpion Centruroides limpidus limpidus Karsch

21 January 2018

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12 December 2020

Antibody framework residues affecting the conformation of the hypervariable loops

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12 December 2020

Monoclonal antibodies neutralizing the toxin II from Androctonus australis hector scorpion venom: usefulness of a synthetic, non-toxic analog

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12 December 2020

Increased affinity leads to improved selective tumor delivery of single-chain Fv antibodies

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12 December 2020

Identifiers

DOI

10.1074/JBC.M110.189175

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21156801%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21156801%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

21156801

1 reference