The radiotherapeutic injury--a complex 'wound'. (Q34683628)

3 August 2017

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title

The radiotherapeutic injury--a complex 'wound'. (English)

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3 August 2017

James W Denham

1

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Martin Hauer-Jensen

series ordinal

2

object named as

Martin Hauer-Jensen

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3 August 2017

1 May 2002

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Radiotherapy and Oncology

3 August 2017

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3 August 2017

63

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3 August 2017

129-145

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3 August 2017

2

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Timing of concomitant boost irradiation affects incidence and severity of intestinal complications

3 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

THE SYNERGISM OF X-IRRADIATION AND CHOLESTEROL-FAT FEEDING ON THE DEVELOPMENT OF CORONARY ARTERY LESIONS

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Wound complications in the multimodality treatment of extremity and superficial truncal sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Correlation of the dermal microvasculature morphology with the epidermal and the endothelial population changes produced by single X ray fractions of 1649, 2231 and 2619 rad in swine

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Arterial hypertension and irradiation damage to the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Sensitisation of blood-vessels to hypertensive damage by x-irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Chemotactic response of monocytes to thrombin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Ionizing radiation induces human intercellular adhesion molecule-1 in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Patient-to-patient variability in the expression of radiation-induced normal tissue injury

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Relationship between early and late normal-tissue injury after postmastectomy radiotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Thrombin-induced chemotaxis and aggregation of neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

The radiobiology of intravascular irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Mitogenic activity of blood components. I. Thrombin and prothrombin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Striking regression of chronic radiotherapy damage in a clinical trial of combined pentoxifylline and tocopherol

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Abnormal phenotype of cultured fibroblasts in human skin with chronic radiotherapy damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Major interactions between radiation therapy and systemic sclerosis: is there an optimal treatment?

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Modulation of vascular endothelial permeability by thrombin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Treatment-time-dependence models of early and delayed radiation injury in rat small intestine

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Is it time for a new formalism to categorize normal tissue radiation injury?

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Extinction of the weakest

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

1 reference

7 January 2021

Do acute mucosal reactions lead to consequential late reactions in patients with head and neck cancer?

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Mucosal regeneration during radiotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

The effects of radiation on neovascularization in a rat model

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Radiation-induced changes in cellularity and proliferation in human oral mucosa

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Proliferation equivalent of 'accelerated repopulation' in mouse oral mucosa

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Consequential late effects in normal tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Effects of irradiation on endothelial cell-polymorphonuclear leukocyte interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Capillary Injury Preceding Radiation-Induced Myocardial Fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Safety of 125iodine and 192iridium implants to the canine carotid artery: preliminary report

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Therapeutic approaches to organ fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Radiation tolerance and the new biology: growth factor involvement in radiation injury to the lung

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Oxidation of a specific methionine in thrombomodulin by activated neutrophil products blocks cofactor activity. A potential rapid mechanism for modulation of coagulation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Effect of fibroblast implants on wound healing of irradiated skin: assay of wound strength and quantitative immunohistology of collagen

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Collagen synthesis by human intestinal smooth muscle cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

E-selectin gene induction by ionizing radiation is independent of cytokine induction

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Sialyl Lewis X mimetics attenuate E-selectin-mediated adhesion of leukocytes to irradiated human endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Effects of accelerated fractionation on radiation injury of the small intestine: a new rat model

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Intestinal complications following accelerated fractionated x-irradiation. An experimental study in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Diabetes mellitus: a predictor for late radiation morbidity

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Normal tissue radiobiology: from the laboratory to the clinic.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Volume effects in radiobiology as applied to radiotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

The nature of latent cerebral irradiation damage and its modification by hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Acute radiation proctitis: a sequential clinicopathologic study during pelvic radiotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Risks of head and neck surgery in previously irradiated patients

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Quantification of late complications after radiation therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Irradiation twenty-four hours preoperatively

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Termination of acute-phase response: role of some cytokines and anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Effects of ionizing irradiation on endothelial cell transglutaminase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Characterization and applications of the disc angiogenesis system

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Changes in transforming growth factor-beta (TGF-beta 1), procollagen types I and II mRNA in the rat heart after irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Contributions to the study of immediate and early x-ray reactions with regard to chemo-protection. VII. X-ray-induced atheromatous lesions in the arterial wall of hypercholesterolaemic rabbits

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Influence of fraction size on the development of late radiation enteropathy. An experimental study in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Significance of overall treatment time for the development of radiation-induced intestinal complications. An experimental study in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Successful treatment of radiation-induced fibrosis using Cu/Zn-SOD and Mn-SOD: an experimental study

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Aortic Arteriosclerosis in the Dog After Localized Aortic X-lrradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Temporal modulation of TGF-beta 1 and beta-actin gene expression in pig skin and muscular fibrosis after ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Abnormal proliferation and aging of cultured fibroblasts from pigs with subcutaneous fibrosis induced by gamma irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Protection of transforming growth factor-beta 1 activity by heparin and fucoidan

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Influence of dose-rate on inflammatory damage and adhesion molecule expression after abdominal radiation in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Transcriptional regulation of intercellular adhesion molecule-1: PMA-induction is mediated by NF kappa B

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Modeling of normal tissue response to radiation: the critical volume model.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Vascular smooth muscle cell migration mediated by thrombin and urokinase receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Wound complications of adjuvant radiation therapy in patients with soft-tissue sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Early postoperative brachytherapy following free flap reconstruction

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Role of leukocyte-endothelial cell adhesion in radiation-induced microvascular dysfunction in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Accelerated fractionation in the radiation treatment of head and neck cancer. A critical comparison of different strategies

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Thrombin stimulates fibroblast-mediated collagen lattice contraction by its proteolytically activated receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Effects of X Irradiation on Angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Effect of thrombin inhibition with desulfatohirudin on early kinetics of cellular proliferation after balloon angioplasty in atherosclerotic rabbits

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Radiosensitivity of capillary endothelium

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Is the loss of endothelial thrombomodulin involved in the mechanism of chronicity in late radiation enteropathy?

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Increased transforming growth factor beta (TGF-beta) immunoreactivity is independently associated with chronic injury in both consequential and primary radiation enteropathy.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Cellular basis of radiation-induced fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

High and low dose rate irradiation have opposing effects on cytokine gene expression in human glioblastoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Acute and late reactions to radiation therapy in patients with collagen vascular diseases.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Prostacyclin synthesis in irradiated endothelial cells cultured from bovine aorta

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Molecular biology mechanisms in the radiation induction of pulmonary injury syndromes: interrelationship between the alveolar macrophage and the septal fibroblast

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

The ultrastructure and etiology of chronic radiotherapy damage in human skin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Slowed Growth of Cultured Fibroblasts from Human Radiation Wounds

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

HISTOLOGICAL CHANGES IN THE LARGER BLOOD VESSELS OF THE HIND LIMB OF THE MOUSE AFTER X-IRRADIATION

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Regulation of tumor necrosis factor gene expression by ionizing radiation in human myeloid leukemia cells and peripheral blood monocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Do inflammatory processes contribute to radiation induced erythema observed in the skin of humans?

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Radiosensitivity in vitro of human fibroblasts derived from patients with a severe skin reaction to radiation therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Preferential impairment of nitric oxide-mediated endothelium-dependent relaxation in human cervical arteries after irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Wound healing following radiation therapy: a review

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Organizational response of normal tissues to irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

The mechanisms of acceleration of repopulation in squamous epithelia during daily irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Radiobiological mechanisms of anti-inflammatory radiotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Acute radiation effects on the content and release of plasminogen activator activity in cultured aortic endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Prognostic factors for acute and late skin reactions in radiotherapy patients

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Repair capacity and kinetics of human skin during fractionated radiotherapy: erythema, desquamation, and telangiectasia after 3 and 5 year's follow-up

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Effects of x-radiation on growth and function of the repair blastema (granulation tissue). I. Wound contraction

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Changes in lung morphology and cell number in radiation pneumonitis and fibrosis: a quantitative ultrastructural study

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Radiation-induced hypoxia may perpetuate late normal tissue injury

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Radiation Hypertension and Nephrosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Radiation-induced alteration of rat mesangial cell transforming growth factor-beta and expression of the genes associated with the extracellular matrix

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Deficiency of microvascular thrombomodulin and up-regulation of protease-activated receptor-1 in irradiated rat intestine: possible link between endothelial dysfunction and chronic radiation fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

The synthetic somatostatin analogue, octreotide, ameliorates acute and delayed intestinal radiation injury

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Cellular sources of transforming growth factor-beta isoforms in early and chronic radiation enteropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Radiation-induced pulmonary endothelial dysfunction in rats: modification by an inhibitor of angiotensin converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Captopril reduces collagen and mast cell accumulation in irradiated rat lung

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Expression of CCR2 by endothelial cells : implications for MCP-1 mediated wound injury repair and In vivo inflammatory activation of endothelium

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Modification of collagen and noncollagenous proteins in radiation-induced muscular fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Accumulation of glycosaminoglycans in radiation-induced muscular fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Thrombin stimulates production of transforming growth factor-beta by cultured human mesangial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Irradiation effects on wound contraction using a connective tissue model.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Role of mast cells in early and delayed radiation injury in rat intestine

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Recombinant soluble transforming growth factor beta type II receptor ameliorates radiation enteropathy in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

Thrombomodulin as a marker of radiation-induced endothelial cell injury

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2802%2900060-9

7 January 2021

10.1016/S0167-8140(02)00060-9

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

12063002