Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1. (Q34683987)

3 August 2017

Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1. (English)

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3 August 2017

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5

Kazuma Ohyashiki

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3 August 2017

Tomohiro Umezu

1

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3 August 2017

Hiroko Tadokoro

2

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3 August 2017

Kenko Azuma

3

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3 August 2017

Seiichiro Yoshizawa

4

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3 August 2017

Junko H Ohyashiki

6

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3 August 2017

language of work or name

English

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publication date

15 October 2014

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3 August 2017

10

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inferred from page(s)

published in

Blood

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3 August 2017

124

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3 August 2017

3748-3757

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3 August 2017

25

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describes a project that uses

3 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4263983/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Upregulation of miR-135b is involved in the impaired osteogenic differentiation of mesenchymal stem cells derived from multiple myeloma patients

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The hypoxia target adrenomedullin is aberrantly expressed in multiple myeloma and promotes angiogenesis.

7 July 2018

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Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction.

7 July 2018

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MicroRNA-135b acts as a tumor promoter by targeting the hypoxia-inducible factor pathway in genetically defined mouse model of head and neck squamous cell carcinoma

7 July 2018

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7 July 2018

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Expression of miR-21, miR-31, miR-96 and miR-135b is correlated with the clinical parameters of colorectal cancer

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7 July 2018

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Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features

7 July 2018

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Biological aspects of angiogenesis in multiple myeloma.

7 July 2018

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miR-135b mediates NPM-ALK-driven oncogenicity and renders IL-17-producing immunophenotype to anaplastic large cell lymphoma.

7 July 2018

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7 July 2018

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7 July 2018

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The use of novel agents in the treatment of relapsed and refractory multiple myeloma

7 July 2018

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Unraveling the biology of multiple myeloma disease: cancer stem cells, acquired intracellular changes and interactions with the surrounding micro-environment

7 July 2018

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7 July 2018

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Detection and specific targeting of hypoxic regions within solid tumors: current preclinical and clinical strategies

7 July 2018

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7 July 2018

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7 July 2018

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Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets

7 July 2018

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The pathophysiologic role of VEGF in hematologic malignancies: therapeutic implications

7 July 2018

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Molecular basis of angiogenesis and cancer

7 July 2018

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FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

7 July 2018

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Bone marrow angiogenesis and progression in multiple myeloma.

7 July 2018

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Clinical drug resistance linked to interconvertible phenotypic and functional states of tumor-propagating cells in multiple myeloma.

7 July 2018

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26 October 2018

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Role of the hypoxic bone marrow microenvironment in 5T2MM murine myeloma tumor progression.

26 October 2018

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Increased bone marrow microvessel density in newly diagnosed multiple myeloma carries a poor prognosis

26 October 2018

1 reference

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Vascular endothelial growth factor and interleukin-6 in paracrine tumor-stromal cell interactions in multiple myeloma

26 October 2018

1 reference

12 December 2020

Proangiogenic properties of human myeloma cells: production of angiopoietin-1 and its potential relationship to myeloma-induced angiogenesis

1 reference

12 December 2020

Human myeloma cells express the bone regulating gene Runx2/Cbfa1 and produce osteopontin that is involved in angiogenesis in multiple myeloma patients

1 reference

12 December 2020

Prognostic value of bone marrow angiogenesis in multiple myeloma

1 reference

12 December 2020

10.1182/BLOOD-2014-05-576116

Identifiers

DOI

1 reference

3 August 2017

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3 August 2017

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