Do ligand binding and solvent exclusion alter the electrostatic character within the oxyanion hole of an enzymatic active site? (Q34686869)

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Do ligand binding and solvent exclusion alter the electrostatic character within the oxyanion hole of an enzymatic active site?
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    Do ligand binding and solvent exclusion alter the electrostatic character within the oxyanion hole of an enzymatic active site? (English)

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