Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations (Q34691553)

25223734

4 August 2017

title

Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations (English)

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4 August 2017

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St. Jude Children's Research Hospital–Washington University Pediatric Cancer Genome Project and the International Cancer Genome Consortium

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describes a project that uses

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The genomic landscape of the Ewing Sarcoma family of tumors reveals recurrent STAG2 mutation

1 reference

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The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes.

7 July 2018

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Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma.

7 July 2018

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Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors

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Targeting oxidative stress in embryonal rhabdomyosarcoma.

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Frequent inactivating mutations of STAG2 in bladder cancer are associated with low tumour grade and stage and inversely related to chromosomal copy number changes

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Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy.

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7 July 2018

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Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes

7 July 2018

1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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Mutational inactivation of STAG2 causes aneuploidy in human cancer

7 July 2018

1 reference

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1q gain and CDT2 overexpression underlie an aggressive and highly proliferative form of Ewing sarcoma

7 July 2018

1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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Prognostic impact of chromosomal aberrations in Ewing tumours

7 July 2018

1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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Recurrent gains of 1q, 8 and 12 in the Ewing family of tumours by comparative genomic hybridization

7 July 2018

1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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26 October 2018

1 reference

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Primary disseminated multifocal Ewing sarcoma: results of the Euro-EWING 99 trial.

26 October 2018

1 reference

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26 October 2018

1 reference

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26 October 2018

1 reference

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Genetic imbalances revealed by comparative genomic hybridization in Ewing tumors

9 December 2018

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12 December 2020

Analysis of the p16INK4, p14ARF, p15, TP53, and MDM2 genes and their prognostic implications in osteosarcoma and Ewing sarcoma

1 reference

12 December 2020

A Multiplex Real-Time PCR Assay for the Detection of Gene Fusions Observed in Solid Tumors

1 reference

12 December 2020

Chromosomes in Ewing's sarcoma. II. Nonrandom additional changes, trisomy 8 and der(16)t(1;16)

1 reference

12 December 2020

Molecular analysis of the 9p21 locus and p53 genes in Ewing family tumors

1 reference

12 December 2020

10.1158/2159-8290.CD-14-0622

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