Tauopathic changes in the striatum of A53T α-synuclein mutant mouse model of Parkinson's disease (Q34704153)

4 August 2017

Tauopathic changes in the striatum of A53T α-synuclein mutant mouse model of Parkinson's disease (English)

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4 August 2017

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Jonathan Wills

1

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4 August 2017

Joel Credle

2

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4 August 2017

Thomas Haggerty

3

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4 August 2017

Jae-Hoon Lee

4

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4 August 2017

Adam W Oaks

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4 August 2017

Anita Sidhu

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4 August 2017

language of work or name

English

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publication date

21 March 2011

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4 August 2017

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4 August 2017

6

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4 August 2017

3

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4 August 2017

e17953

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Creative Commons Attribution 4.0 International

4 August 2017

start time

21 March 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3061878/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinson's disease brains with and without dementia

7 July 2018

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Alpha-Synuclein contributes to GSK-3beta-catalyzed Tau phosphorylation in Parkinson's disease models

7 July 2018

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Regulated interactions of the norepineprhine transporter by the actin and microtubule cytoskeletons

7 July 2018

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Site-specific effects of tau phosphorylation on its microtubule assembly activity and self-aggregation

7 July 2018

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Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system

7 July 2018

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Alpha-synuclein induces hyperphosphorylation of Tau in the MPTP model of parkinsonism

7 July 2018

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The neurotoxin, MPP+, induces hyperphosphorylation of Tau, in the presence of alpha-Synuclein, in SH-SY5Y neuroblastoma cells

7 July 2018

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Highly potent and specific GSK-3beta inhibitors that block tau phosphorylation and decrease alpha-synuclein protein expression in a cellular model of Parkinson's disease.

7 July 2018

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Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits

7 July 2018

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Interleukin-1 mediates Alzheimer and Lewy body pathologies.

7 July 2018

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GSK3B polymorphisms alter transcription and splicing in Parkinson's disease

7 July 2018

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Striatal expression of GDNF and differential vulnerability of midbrain dopaminergic cells.

7 July 2018

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The role of alpha-synuclein in both neuroprotection and neurodegeneration

7 July 2018

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7 July 2018

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Tyrosine-to-cysteine modification of human alpha-synuclein enhances protein aggregation and cellular toxicity

7 July 2018

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Colocalization of Tau and Alpha-Synuclein Epitopes in Lewy Bodies

7 July 2018

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Concurrence of alpha-synuclein and tau brain pathology in the Contursi kindred

7 July 2018

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Tau and alpha-synuclein pathology in amygdala of Parkinsonism-dementia complex patients of Guam

7 July 2018

1 reference

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Lewy bodies in Alzheimer's disease: a neuropathological review of 145 cases using alpha-synuclein immunohistochemistry.

7 July 2018

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Hyperphosphorylated tau in SY5Y cells: similarities and dissimilarities to abnormally hyperphosphorylated tau from Alzheimer disease brain

7 July 2018

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Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes

7 July 2018

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Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules

7 July 2018

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

7 July 2018

1 reference

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

7 July 2018

1 reference

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Lewy body diseases and multiple system atrophy as alpha-synucleinopathies.

7 July 2018

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Alpha-synuclein-positive structures in cases with sporadic Alzheimer's disease: morphology and its relationship to tau aggregation.

21 January 2018

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Tau pathology in the olfactory bulb correlates with Braak stage, Lewy body pathology and apolipoprotein epsilon4.

21 January 2018

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Abundant neuritic inclusions and microvacuolar changes in a case of diffuse Lewy body disease with the A53T mutation in the alpha-synuclein gene.

21 January 2018

1 reference

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Fibrillization of alpha-synuclein and tau in familial Parkinson's disease caused by the A53T alpha-synuclein mutation

21 January 2018

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Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.

21 January 2018

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Loss of response to levodopa in Parkinson's disease and co-occurrence with dementia: role of D3 and not D2 receptors

21 January 2018

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Role of oxidative stress in paraquat-induced dopaminergic cell degeneration.

21 January 2018

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Conformational change as one of the earliest alterations of tau in Alzheimer's disease.

21 January 2018

1 reference

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Phosphorylation of tau and alpha-synuclein in synaptic-enriched fractions of the frontal cortex in Alzheimer's disease, and in Parkinson's disease and related alpha-synucleinopathies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017953

Tau phosphorylation increases in symptomatic mice overexpressing A30P alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017953

The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017953

Phosphorylation of tau by glycogen synthase kinase 3beta affects the ability of tau to promote microtubule self-assembly

21 January 2018

1 reference

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Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017953

Proline-directed pseudo-phosphorylation at AT8 and PHF1 epitopes induces a compaction of the paperclip folding of Tau and generates a pathological (MC-1) conformation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061878

Cross-linking of ubiquitin, HSP27, parkin, and alpha-synuclein by gamma-glutamyl-epsilon-lysine bonds in Alzheimer's neurofibrillary tangles

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061878

Lewy body variant of Alzheimer's disease and Alzheimer's disease: a comparative immunohistochemical study.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061878

C-terminal inhibition of tau assembly in vitro and in Alzheimer's disease.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061878

Frequent coexistence of Lewy bodies and neurofibrillary tangles in the same neurons of patients with diffuse Lewy body disease

26 October 2018

1 reference

12 December 2020

Filamentous nerve cell inclusions in neurodegenerative diseases

1 reference

12 December 2020

The role of alpha-synuclein gene multiplications in early-onset Parkinson's disease and dementia with Lewy bodies

1 reference

12 December 2020

Alpha-synuclein inclusions in amygdala in the brains of patients with the parkinsonism-dementia complex of Guam

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0017953

Identifiers

DOI

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4 August 2017

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4 August 2017

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