A novel defensive mechanism against acetaminophen toxicity in the mouse lateral nasal gland: role of CYP2A5-mediated regulation of testosterone homeostasis and salivary androgen-binding protein expression. (Q34715641)

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English	A novel defensive mechanism against acetaminophen toxicity in the mouse lateral nasal gland: role of CYP2A5-mediated regulation of testosterone homeostasis and salivary androgen-binding protein expression.	scientific article

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20 January 2020

A novel defensive mechanism against acetaminophen toxicity in the mouse lateral nasal gland: role of CYP2A5-mediated regulation of testosterone homeostasis and salivary androgen-binding protein expression (English)

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20 January 2020

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2

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20 January 2020

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Xin Zhou

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20 January 2020

Fang Xie

3

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20 January 2020

Christina M Laukaitis

4

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20 January 2020

Robert C Karn

5

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20 January 2020

Kerri Kluetzman

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20 January 2020

Jun Gu

7

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20 January 2020

Qing-Yu Zhang

8

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20 January 2020

Dean W Roberts

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20 January 2020

Xinxin Ding

10

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20 January 2020

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20 January 2011

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20 January 2020

Molecular Pharmacology

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20 January 2020

79

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20 January 2020

4

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20 January 2020

710-723

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20 January 2020

Role of CYP2A5 in the clearance of nicotine and cotinine: insights from studies on a Cyp2a5-null mouse model

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7 July 2018

High abundance of testosterone and salivary androgen-binding protein in the lateral nasal gland of male mice

1 reference

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7 July 2018

Sex-dependent disposition of acetaminophen sulfate and glucuronide in the in situ perfused mouse liver.

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7 July 2018

Rapid bursts of androgen-binding protein (Abp) gene duplication occurred independently in diverse mammals

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7 July 2018

Hepatic gene expression changes in mouse models with liver-specific deletion or global suppression of the NADPH-cytochrome P450 reductase gene. Mechanistic implications for the regulation of microsomal cytochrome P450 and the fatty liver phenotype

1 reference

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7 July 2018

Effects of 8-methoxypsoralen on cytochrome P450 2A13.

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7 July 2018

Acetaminophen-induced hepatotoxicity: role of metabolic activation, reactive oxygen/nitrogen species, and mitochondrial permeability transition

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7 July 2018

Regulation of the cytochrome P450 2A genes

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7 July 2018

Cell-specific Expression of CYP2A5 in the Mouse Respiratory Tract: Effects of Olfactory Toxicants

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7 July 2018

Characterization of two forms of mouse salivary androgen-binding protein (ABP): implications for evolutionary relationships and ligand-binding function

1 reference

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7 July 2018

Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantation

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7 July 2018

Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs

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7 July 2018

Steroid binding by mouse salivary proteins

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7 July 2018

Cloning and expression of odorant-binding proteins Ia and Ib from mouse nasal tissue

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7 July 2018

Baculovirus-mediated expression and characterization of rat CYP2A3 and human CYP2a6: role in metabolic activation of nasal toxicants.

1 reference

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7 July 2018

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

1 reference

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7 July 2018

Targeted disruption of the MHC class II Aa gene in C57BL/6 mice

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7 July 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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7 July 2018

The fine structure of the lateral nasal gland (Steno's gland) of the rat.

1 reference

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7 July 2018

Production of an antibody to mouse salivary androgen binding protein (ABP) and its use in identifying a prostate protein produced by a gene distinct from Abp

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063730

7 July 2018

A sensitive immunochemical assay for acetaminophen-protein adducts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063730

7 July 2018

The genes for mouse salivary androgen-binding protein (ABP) subunits alpha and gamma are located on chromosome 7.

1 reference

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7 July 2018

Androgen regulation of secretory component synthesis by lacrimal gland acinar cells in vitro

1 reference

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7 July 2018

Immunochemical characterization of multiple forms of cytochrome P-450 in rabbit nasal microsomes and evidence for tissue-specific expression of P-450s NMa and NMb.

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7 July 2018

Contribution of acetaminophen-cysteine to acetaminophen nephrotoxicity II. Possible involvement of the gamma-glutamyl cycle

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26 October 2018

Contribution of acetaminophen-cysteine to acetaminophen nephrotoxicity in CD-1 mice: I. Enhancement of acetaminophen nephrotoxicity by acetaminophen-cysteine

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26 October 2018

In vivo mechanisms of tissue-selective drug toxicity: effects of liver-specific knockout of the NADPH-cytochrome P450 reductase gene on acetaminophen toxicity in kidney, lung, and nasal mucosa

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26 October 2018

Targeted Disruption of the Olfactory Mucosa-SpecificCyp2g1Gene: Impact on Acetaminophen Toxicity in the Lateral Nasal Gland, and Tissue-Selective Effects onCyp2a5Expression

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26 October 2018

Hepatobiliary excretion of acetaminophen glutathione conjugate and its derivatives in transport-deficient (TR-) hyperbilirubinemic rats

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26 October 2018

Purification and characterization of heterologously expressed mouse CYP2A5 and CYP2G1: role in metabolic activation of acetaminophen and 2,6-dichlorobenzonitrile in mouse olfactory mucosal microsomes

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26 October 2018

The amino acid sequence of the alpha subunit of mouse salivary androgen-binding protein (ABP), with a comparison to the partial sequence of the beta subunit and to other ligand-binding proteins

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26 October 2018

Epitope characterization of acetaminophen bound to protein and nonprotein sulfhydryl groups by an enzyme-linked immunosorbent assay

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12 December 2020

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Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics

1 reference

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12 December 2020

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Cytochrome P450 and steroid hydroxylase activity in mouse olfactory and vomeronasal mucosa

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steroid metabolism by rabbit olfactory-specific P450 2G1

1 reference

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12 December 2020

based on heuristic

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Role of CYP1A2 in the hepatotoxicity of acetaminophen: investigations using Cyp1a2 null mice

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of cytochrome p450 and other biotransformation genes in fetal and adult human nasal mucosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/21252290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation by androgens of the production of androgen binding protein by cultured Sertoli cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21252290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histopathologic examination of the rat nasal cavity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21252290

12 December 2020

based on heuristic

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Identifiers

10.1124/MOL.110.070045

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20 January 2020

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20 January 2020

PubMed publication ID

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20 January 2020

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