Endothelin-1 as a target for therapeutic intervention in prostate cancer (Q34722259)

4 August 2017

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title

Endothelin-1 as a target for therapeutic intervention in prostate cancer (English)

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4 August 2017

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E Scott Kopetz

1

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4 August 2017

Joel B Nelson

series ordinal

2

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4 August 2017

Michael A Carducci

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3

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4 August 2017

1 May 2002

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Investigational New Drugs

4 August 2017

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4 August 2017

20

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4 August 2017

2

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4 August 2017

173-182

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https://scigraph.springernature.com/pub.10.1023/a:1015630513908

4 August 2017

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Expression and localization of endothelin-1 and endothelin receptors in human meningiomas. Evidence for a role in tumoral growth

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Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1

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Endothelin-induced nociception in mice: mediation by ETA and ETB receptors

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Gene expression and autoradiographic localization of endothelin-1 and its receptors A and B in the different zones of the normal human prostate

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Autocrine actions of endothelin-1 as a growth factor in human ovarian carcinoma cells

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Localization of endothelin receptors in the human prostate

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Augmented expression of endothelin-1, endothelin-3 and the endothelin-B receptor in breast carcinoma

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Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells

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Endothelin-1 activates phospholipase C and mobilizes Ca2+ from extra- and intracellular pools in osteoblastic cells

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Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo.

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Upregulation of endothelin 1 and its precursor by IL-1beta, TNF-alpha, and TGF-beta in the PC3 human prostate cancer cell line

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Autoregulation of endothelin-1 secretion by cultured human keratinocytes via the endothelin B receptor

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Defining the role of endothelins in renal pathophysiology on the basis of selective and unselective endothelin receptor antagonist studies

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Endothelin-1 enhances vascular permeability in the rat heart through the ETA receptor

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Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice

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Endothelin-1 in the human prostate: tissue levels, source of production and isometric tension studies

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Identification of endothelin–1 in the pathophysiology of metastatic adenocarcinoma of the prostate

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12 December 2020

Regional haemodynamic effects of endothelin-1 in rat and man: unexpected adverse reaction

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Articular nociception induced by endothelin-1, carrageenan and LPS in naive and previously inflamed knee-joints in the rat: inhibition by endothelin receptor antagonists

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Endothelin-1 stimulates human monocytes in vitro to release TNF-alpha , IL-1beta and IL-6.

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12 December 2020

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12 December 2020

Endothelin-1 actions on resorption, collagen and noncollagen protein synthesis, and phosphatidylinositol turnover in bone organ cultures

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12 December 2020

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12 December 2020

Endothelins: circulating plasma levels and presence in other biologic fluids

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12 December 2020

Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide

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12 December 2020

A selective endothelin ETA antagonist, BQ-123, inhibits 125I-endothelin-1 (125I-ET-1) binding to human meningiomas and antagonizes ET-1-induced proliferation of meningioma cells

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12 December 2020

ETB receptors promote proliferation and migration of endothelial cells

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12 December 2020

Endothelin and the central and peripheral nervous systems: a decade of endothelin research

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12 December 2020

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

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12 December 2020

Radioimmunoassay of endothelin

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12 December 2020

Proliferation and migration of endothelial cells is promoted by endothelins via activation of ETB receptors

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12 December 2020

Co-operation between endothelin and nitric oxide in promoting endothelial cell migration and angiogenesis

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12 December 2020

Dual control of cell growth by somatomedins and platelet-derived growth factor

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12 December 2020

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12 December 2020

Methylation of the 5' CpG island of the endothelin B receptor gene is common in human prostate cancer.

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12 December 2020

Endothelin-1 enhances capsaicin-induced peptide release and cGMP accumulation in cultures of rat sensory neurons

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12 December 2020

Endothelin (ET)-3 stimulates cyclic guanosine 3',5'-monophosphate production via ETB receptor by producing nitric oxide in isolated rat glomerulus, and in cultured rat mesangial cells

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12 December 2020

Decreased ET(B) receptor expression in human metastatic melanoma cells

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12 December 2020

Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons

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12 December 2020

Endothelin-A receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade.

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12 December 2020

Massive amounts of immunoreactive endothelin in human seminal fluid

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12 December 2020

Studies on the expression of endothelin, its receptor subtypes, and converting enzymes in lung cancer and in human bronchial epithelium

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12 December 2020

Protein kinase C and protein tyrosine kinase activity contribute to mitogenic signaling by endothelin-1. Cross-talk between G protein-coupled receptors and pp60c-src

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12 December 2020

Paracrine regulation of ovarian cancer by endothelin

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12 December 2020

Endothelin-1-induced ET(A) receptor-mediated nociception, hyperalgesia and oedema in the mouse hind-paw: modulation by simultaneous ET(B) receptor activation

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12 December 2020

Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancer

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12 December 2020

Behavioral signs of acute pain produced by application of endothelin-1 to rat sciatic nerve.

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12 December 2020

Endothelin-1 from prostate cancer cells is enhanced by bone contact which blocks osteoclastic bone resorption

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12 December 2020

Regulation and intracellular trafficking pathways of the endothelin receptors

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12 December 2020

Roles of nitric oxide in tumor growth

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12 December 2020

Subcellular mechanisms of endothelin action in vascular system

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12 December 2020

Vasoactive peptides modulate vascular endothelial cell growth factor production and endothelial cell proliferation and invasion

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12 December 2020

Endothelin in human plasma and culture medium of aortic endothelial cells--detection and characterization with radioimmunoassay using monoclonal antibody

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12 December 2020

Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway

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12 December 2020

Analysis of the role of endothelin-A and endothelin-B receptors on nociceptive information transmission in the spinal cord with FR139317, an endothelin-A receptor antagonist, and sarafotoxin S6c, an endothelin-B receptor agonist

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12 December 2020

Platelet-derived growth factor A and B chains and the alpha and beta receptors in prostatic intraepithelial neoplasia

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12 December 2020

N-methyl-D-aspartate-induced excessive formation of nitric oxide in CHP100 neuroblastoma cells produces death of BMEL melanoma cells in co-culture.

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12 December 2020

Molecular and functional characterization of the non-isopeptide-selective ETB receptor in endothelial cells. Receptor coupling to nitric oxide synthase

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12 December 2020

Endothelin modulates osteopontin and osteocalcin messenger ribonucleic acid expression in rat osteoblastic osteosarcoma cells

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12 December 2020

Rat endothelin is a vasodilator in the isolated perfused mesentery of the rat

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12 December 2020

Endothelins in the urinary tract

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12 December 2020

Identifiers

DOI

10.1023/A:1015630513908

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Dimensions Publication ID

4 August 2017

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