Structural elements of the cholesterol-dependent cytolysins that are responsible for their cholesterol-sensitive membrane interactions (Q34724964)

4 August 2017

Structural elements of the cholesterol-dependent cytolysins that are responsible for their cholesterol-sensitive membrane interactions (English)

1 reference

4 August 2017

Casie E Soltani

1

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4 August 2017

Eileen M Hotze

series ordinal

2

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4 August 2017

Arthur E Johnson

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3

1 reference

4 August 2017

Rodney K Tweten

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4

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4 August 2017

language of work or name

English

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publication date

12 December 2007

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Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

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4 August 2017

104

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4 August 2017

20226-20231

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4 August 2017

51

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Specific protein-membrane contacts are required for prepore and pore assembly by a cholesterol-dependent cytolysin

4 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Cholesterol-dependent pore formation of Clostridium difficile toxin A.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Cholesterol-dependent cytolysins, a family of versatile pore-forming toxins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

The domains of a cholesterol-dependent cytolysin undergo a major FRET-detected rearrangement during pore formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Insights into the action of the superfamily of cholesterol-dependent cytolysins from studies of intermedilysin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Human CD59 is a receptor for the cholesterol-dependent cytolysin intermedilysin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Vertical collapse of a cytolysin prepore moves its transmembrane beta-hairpins to the membrane

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Membrane restructuring by Bordetella pertussis adenylate cyclase toxin, a member of the RTX toxin family

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Pleurotolysin, a novel sphingomyelin-specific two-component cytolysin from the edible mushroom Pleurotus ostreatus, assembles into a transmembrane pore complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Reduced sensitivity of Niemann-Pick C1-deficient cells to theta-toxin (perfringolysin O): sequestration of toxin to raft-enriched membrane vesicles

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Redefining cholesterol's role in the mechanism of the cholesterol-dependent cytolysins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Structural insights into the membrane-anchoring mechanism of a cholesterol-dependent cytolysin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Selective binding of perfringolysin O derivative to cholesterol-rich membrane microdomains (rafts).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Mechanism of membrane insertion of a multimeric beta-barrel protein: perfringolysin O creates a pore using ordered and coupled conformational changes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Specific roles for lipids in virus fusion and exit. Examples from the alphaviruses.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

The conserved undecapeptide shared by thiol-activated cytolysins is involved in membrane binding

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Cholesterol-Streptolysin O Interaction: An EM Study of Wild-Type and Mutant Streptolysin O.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Intermedilysin, a novel cytotoxin specific for human cells secreted by Streptococcus intermedius UNS46 isolated from a human liver abscess

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

VMD: visual molecular dynamics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Binding of cholesterol by sulfhydryl-activated cytolysins.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Structural characteristics of tetanolysin and its binding to lipid vesicles

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Disruption of Wall-less Bacteria by Streptococcal and Staphylococcal Toxins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Evidence for membrane cholesterol as the common binding site for cereolysin, streptolysin O and saponin.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Pneumolysin, the thiol-activated toxin of Streptococcus pneumoniae, does not require a thiol group for in vitro activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

Inhibition of homologous complement by CD59 is mediated by a species-selective recognition conferred through binding to C8 within C5b-8 or C9 within C5b-9.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2154413

The C-terminal domain of perfringolysin O is an essential cholesterol-binding unit targeting to cholesterol-rich microdomains.

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0708104105

Contribution of individual tryptophan residues to the structure and activity of theta-toxin (perfringolysin O), a cholesterol-binding cytolysin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0708104105

Contribution of tryptophan residues to the structural changes in perfringolysin O during interaction with liposomal membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0708104105

The human-specific action of intermedilysin, a homolog of streptolysin O, is dictated by domain 4 of the protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0708104105

Lipid phase coexistence favors membrane insertion of equinatoxin-II, a pore-forming toxin from Actinia equina.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0708104105

Vibrio cholerae hemolysin. Implication of amphiphilicity and lipid-induced conformational change for its pore-forming activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0708104105

Cholesterol and Lipid/Protein Ratio Control the Oligomerization of a Sphingomyelin-Specific Toxin, Lysenin†

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0708104105

Identification of a Membrane-Spanning Domain of the Thiol-Activated Pore-Forming ToxinClostridium perfringensPerfringolysin O: An α-Helical to β-Sheet Transition Identified by Fluorescence Spectroscopy†

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0708104105

The mechanism of pore assembly for a cholesterol-dependent cytolysin: formation of a large prepore complex precedes the insertion of the transmembrane beta-hairpins

21 January 2018

1 reference

12 December 2020

A cholesterol fraction for streptolysin O binding in cell membranes and lipoproteins--II. Interaction of streptolysin O with phospholipid-cholesterol liposomes of different nature and molar ratios

1 reference

12 December 2020

Preliminary evidence that different domains are involved in cytolytic activity and receptor (cholesterol) binding in listeriolysin O, the Listeria monocytogenes thiol-activated toxin

1 reference

12 December 2020

A cholesterol fraction for streptolysin O binding on cell membranes and lipoproteins--I. Optimal conditions for the determination

1 reference

12 December 2020

Interaction of theta-toxin (perfringolysin O), a cholesterol-binding cytolysin, with liposomal membranes: change in the aromatic side chains upon binding and insertion

1 reference

12 December 2020

Role of the essential thiol group in the thiol-activated cytolysin from Clostridium perfringens

1 reference

12 December 2020

LYSIS OF PLEUROPNEUMONIA-LIKE ORGANISMS BY STAPHYLOCOCCAL AND STREPTOCOCCAL TOXINS

1 reference

12 December 2020

Effect of isolated C-terminal fragment of theta-toxin (perfringolysin O) on toxin assembly and membrane lysis

1 reference

12 December 2020

Protease-nicked theta-toxin of Clostridium perfringens, a new membrane probe with no cytolytic effect, reveals two classes of cholesterol as toxin-binding sites on sheep erythrocytes

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0708104105

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4 August 2017

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4 August 2017

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