The development of mature B lymphocytes requires the combined function of CD19 and the p110δ subunit of PI3K (Q34729503)

4 August 2017

title

The development of mature B lymphocytes requires the combined function of CD19 and the p110δ subunit of PI3K (English)

1 reference

4 August 2017

Dorottya Kövesdi

1

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4 August 2017

Sarah E Bell

series ordinal

2

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4 August 2017

Martin Turner

series ordinal

3

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4 August 2017

language of work or name

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11 March 2010

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4 August 2017

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4 August 2017

volume

1

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4 August 2017

issue

2

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4 August 2017

page(s)

144-153

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describes a project that uses

4 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3065673/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Mechanisms promoting translocations in editing and switching peripheral B cells

7 July 2018

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B cell receptor-mediated sustained c-Rel activation facilitates late transitional B cell survival through control of B cell activating factor receptor and NF-kappaB2.

7 July 2018

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BAFF activates Akt and Erk through BAFF-R in an IKK1-dependent manner in primary mouse B cells

7 July 2018

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Foxo1 directly regulates the transcription of recombination-activating genes during B cell development

7 July 2018

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Peripheral B cell subsets

7 July 2018

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B cell receptor basal signaling regulates antigen-induced Ig light chain rearrangements

7 July 2018

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7 July 2018

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The recirculating B cell pool contains two functionally distinct, long-lived, posttransitional, follicular B cell populations

7 July 2018

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Basal B cell receptor-directed phosphatidylinositol 3-kinase signaling turns off RAGs and promotes B cell-positive selection.

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The 3BP2 adapter protein is required for optimal B-cell activation and thymus-independent type 2 humoral response

7 July 2018

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7 July 2018

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Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations

7 July 2018

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Receptor editing for better or for worse

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Double-strand break formation by the RAG complex at the bcl-2 major breakpoint region and at other non-B DNA structures in vitro

7 July 2018

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PI3K signaling controls cell fate at many points in B lymphocyte development and activation

7 July 2018

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Binding of cytoplasmic proteins to the CD19 intracellular domain is high affinity, competitive, and multimeric

7 July 2018

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Role of CD19 signal transduction in B cell biology

7 July 2018

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A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation

7 July 2018

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Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency

7 July 2018

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Antibody regulation of B cell development

7 July 2018

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CD19 regulates Src family protein tyrosine kinase activation in B lymphocytes through processive amplification

7 July 2018

1 reference

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Absence of mature peripheral B cell populations in mice with concomitant defects in B cell receptor and BAFF-R signaling.

7 July 2018

1 reference

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SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K-PKB-Foxo pathway.

26 October 2018

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Regulation of B-cell development by BCAP and CD19 through their binding to phosphoinositide 3-kinase

26 October 2018

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Identification of anergic B cells within a wild-type repertoire.

26 October 2018

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Regulation of class-switch recombination and plasma cell differentiation by phosphatidylinositol 3-kinase signaling

26 October 2018

1 reference

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Key role of the p110delta isoform of PI3K in B-cell antigen and IL-4 receptor signaling: comparative analysis of genetic and pharmacologic interference with p110delta function in B cells

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065673

Vav proteins regulate peripheral B-cell survival

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065673

NF-kappaB inducible genes BCL-X and cyclin E promote immature B-cell proliferation and survival.

26 October 2018

1 reference

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Altered splenic B cell subset development in mice lacking phosphoinositide 3-kinase p85alpha

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065673

The tyrosine kinase Syk is required for light chain isotype exclusion but dispensable for the negative selection of B cells.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065673

FcgammaRIIb-mediated negative regulation of BCR signalling is associated with the recruitment of the MAPkinase-phosphatase, Pac-1, and the 3'-inositol phosphatase, PTEN.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065673

Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065673

Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065673

CD19 function in early and late B cell development: I. Maintenance of follicular and marginal zone B cells requires CD19-dependent survival signals

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065673

The physiologic role of CD19 cytoplasmic tyrosines

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065673

BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065673

Impaired light chain allelic exclusion and lack of positive selection in immature B cells expressing incompetent receptor deficient of CD19.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065673

The tyrosine kinase Lyn is required for B cell development beyond the T1 stage in the spleen: rescue by over-expression of Bcl-2.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065673

Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065673

CD19 as a membrane-anchored adaptor protein of B lymphocytes: costimulation of lipid and protein kinases by recruitment of Vav.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065673

Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065673

Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065673

An Essential Role for BAFF in the Normal Development of B Cells Through a BCMA-Independent Pathway

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065673

Vav proteins are required for B-lymphocyte responses to LPS

9 December 2018

1 reference

12 December 2020

Contribution of BCAP to maintenance of mature B cells through c-Rel

1 reference

12 December 2020

The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF

1 reference

12 December 2020

Distinct signaling requirements for Dmu selection, IgH allelic exclusion, pre-B cell transition, and tumor suppression in B cell progenitors

1 reference

12 December 2020

B-cell responses to B-cell activation factor of the TNF family (BAFF) are impaired in the absence of PI3K delta

1 reference

12 December 2020

CD19 regulates positive selection and maturation in B lymphopoiesis: lack of CD19 imposes developmental arrest of immature B cells and consequential stimulation of receptor editing

1 reference

12 December 2020

CD19 of B cells as a surrogate kinase insert region to bind phosphatidylinositol 3-kinase

1 reference

12 December 2020

The PI3K p110delta is required for down-regulation of RAG expression in immature B cells

1 reference

12 December 2020

Identifiers

DOI

10.4161/SELF.1.2.11796

1 reference

4 August 2017

1 reference

4 August 2017

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