The contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for the immunotherapy of rheumatological diseases (Q34731180)

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English	The contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for the immunotherapy of rheumatological diseases	scientific article

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

7 references

17 June 2019

25 June 2019

12 October 2019

18 October 2019

20 November 2019

9 September 2020

1 May 2021

The contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for the immunotherapy of rheumatological diseases (English)

1 reference

Europe PubMed Central

4 August 2017

1 reference

12 October 2019

hemic and immune systems

1 reference

18 October 2019

1 reference

20 November 2019

2 references

based on heuristic

inferred from title

9 September 2020

1 reference

1 May 2021

author name string

Thomas Waldmann

1

1 reference

Europe PubMed Central

4 August 2017

publication date

9 May 2002

8 references

Europe PubMed Central

4 August 2017

17 June 2019

25 June 2019

12 October 2019

18 October 2019

20 November 2019

9 September 2020

1 May 2021

Arthritis Research and Therapy

1 reference

Europe PubMed Central

4 August 2017

Arthritis Research

7 references

17 June 2019

25 June 2019

12 October 2019

18 October 2019

20 November 2019

9 September 2020

1 May 2021

4 Suppl 3

1 reference

Europe PubMed Central

4 August 2017

S161-7

1 reference

Europe PubMed Central

4 August 2017

https://scigraph.springernature.com/pub.10.1186/ar584

0 references

Certified professionals: CD4(+)CD25(+) suppressor T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Human T cell lymphotropic virus type I Tax activates IL-15R alpha gene expression through an NF-kappa B site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Involvement of IL-15 in the pathogenesis of human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis: implications for therapy with a monoclonal antibody directed to the IL-2/15R beta receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Production of interleukin-7 and interleukin-15 by fibroblast-like synoviocytes from patients with rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Targeting the IL-15 receptor with an antagonist IL-15 mutant/Fc gamma2a protein blocks delayed-type hypersensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Soluble IL-15 receptor alpha-chain administration prevents murine collagen-induced arthritis: a role for IL-15 in development of antigen-induced immunopathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

The 5' untranslated region, signal peptide, and the coding sequence of the carboxyl terminus of IL-15 participate in its multifaceted translational control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Interleukin 15 is produced by endothelial cells and increases the transendothelial migration of T cells In vitro and in the SCID mouse-human rheumatoid arthritis model In vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Human T cell lymphotropic virus type I Tax protein trans-activates interleukin 15 gene transcription through an NF-kappaB site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Characterization of interleukin-15 (IL-15) and the IL-15 receptor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Role of cytokines in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon-gamma by natural killer cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Fas and the art of lymphocyte maintenance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Constitutive activation of different Jak tyrosine kinases in human T cell leukemia virus type 1 (HTLV-1) tax protein or virus-transformed cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

The p75 peptide is the receptor for interleukin 2 expressed on large granular lymphocytes and is responsible for the interleukin 2 activation of these cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

The interleukin-2 receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

7 July 2018

Control of homeostasis of CD8+ memory T cells by opposing cytokines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

26 October 2018

The interleukin-2 receptor: a target for monoclonal antibody treatment of human T-cell lymphotrophic virus I-induced adult T-cell leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

26 October 2018

Development and proliferation of lymphocytes in mice deficient for both interleukins-2 and -4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240159

26 October 2018

Defective lymphoid development in mice lacking Jak3

1 reference

https://pubmed.ncbi.nlm.nih.gov/12110135

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of interleukin–15 in T–cell migration and activation in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12110135

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of IL-15 secretion via the leader peptide of two IL-15 isoforms

1 reference

https://pubmed.ncbi.nlm.nih.gov/12110135

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12110135

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-15 preferentially promotes the growth of intestinal intraepithelial lymphocytes bearing gamma delta T cell receptor in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12110135

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-15 mRNA expression is up-regulated in blood and cerebrospinal fluid mononuclear cells in multiple sclerosis (MS)

1 reference

https://pubmed.ncbi.nlm.nih.gov/12110135

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 15: a proinflammatory role in rheumatoid arthritis synovitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12110135

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/12110135

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The long signal peptide isoform and its alternative processing direct the intracellular trafficking of interleukin-15

1 reference

https://pubmed.ncbi.nlm.nih.gov/12110135

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum cytokines in different histological variants of rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12110135

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Humanized antibody directed to the IL-2 receptor beta-chain prolongs primate cardiac allograft survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/12110135

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12110135

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased numbers of interleukin-15-expressing cells in active ulcerative colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12110135

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-15 and its role in chronic inflammatory diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12110135

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12110135

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

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