Lentiviral vector design for multiple shRNA expression and durable HIV-1 inhibition (Q34733983)

4 August 2017

title

Lentiviral vector design for multiple shRNA expression and durable HIV-1 inhibition (English)

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4 August 2017

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6

Ben Berkhout

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author name string

Olivier ter Brake

1

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4 August 2017

Karen 't Hooft

2

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4 August 2017

Ying Poi Liu

3

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4 August 2017

Mireille Centlivre

4

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4 August 2017

Karin Jasmijn von Eije

5

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4 August 2017

publication date

15 January 2008

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4 August 2017

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4 August 2017

volume

16

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4 August 2017

issue

3

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4 August 2017

page(s)

557-564

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The interplay between virus infection and the cellular RNA interference machinery

4 August 2017

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Lentivirus vectors expressing short hairpin RNAs against the U3-overlapping region of HIV nef inhibit HIV replication and infectivity in primary macrophages

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Novel Pol II fusion promoter directs human immunodeficiency virus type 1-inducible coexpression of a short hairpin RNA and protein.

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Silencing of HIV-1 with RNA interference: a multiple shRNA approach

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HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome

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Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition

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Computational design of antiviral RNA interference strategies that resist human immunodeficiency virus escape.

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Antiretroviral treatment of HIV infected adults

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The Lifetime Cost of Current Human Immunodeficiency Virus Care in the United States

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Combinatorial RNAi: a winning strategy for the race against evolving targets?

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Design of extended short hairpin RNAs for HIV-1 inhibition

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RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model

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Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model

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Lentiviral vector-mediated delivery of short hairpin RNA results in persistent knockdown of gene expression in mouse brain

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Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy

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Human immunodeficiency virus type 1 recombination: rate, fidelity, and putative hot spots

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7 January 2021

High rate of recombination throughout the human immunodeficiency virus type 1 genome

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7 January 2021

RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells

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7 January 2021

RNA interference by small hairpin RNAs synthesised under control of the human 7S K RNA promoter

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7 January 2021

A new vector, based on the PolII promoter of the U1 snRNA gene, for the expression of siRNAs in mammalian cells

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7 January 2021

Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC

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7 January 2021

A Rev-independent human immunodeficiency virus type 1 (HIV-1)-based vector that exploits a codon-optimized HIV-1 gag-pol gene

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7 January 2021

Systematic determination of the packaging limit of lentiviral vectors

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7 January 2021

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An essential role for LEDGF/p75 in HIV integration

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7 January 2021

HIV-1 resistance conferred by siRNA cosuppression of CXCR4 and CCR5 coreceptors by a bispecific lentiviral vector

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7 January 2021

Promoter choice affects the potency of HIV-1 specific RNA interference

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7 January 2021

Poly(U) and polyadenylation termination signals are interchangeable for terminating the expression of shRNA from a pol II promoter

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7 January 2021

The virion-associated incoming HIV-1 RNA genome is not targeted by RNA interference

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7 January 2021

RNA interference directed against viral and cellular targets inhibits human immunodeficiency Virus Type 1 replication

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7 January 2021

Experimental models to study development and function of the human immune system in vivo

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7 January 2021

HIV-1 infection and CD4 T cell depletion in the humanized Rag2-/-gamma c-/- (RAG-hu) mouse model

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7 January 2021

Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses

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7 January 2021

Current status of gene therapy strategies to treat HIV/AIDS.

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7 January 2021

Gene therapy progress and prospects: novel gene therapy approaches for AIDS.

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7 January 2021

Gene transfer in humans using a conditionally replicating lentiviral vector

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7 January 2021

Lentiviral vectors for efficient transduction of isolated primary quiescent hepatocytes

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7 January 2021

Identifiers

DOI

10.1038/SJ.MT.6300382

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4 August 2017

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