The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8(+) T cells to respond to foreign antigens (Q34734561)

4 August 2017

title

The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8(+) T cells to respond to foreign antigens (English)

1 reference

4 August 2017

Stephen C Jameson

7

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Kristin A. Hogquist

object named as

Kristin A Hogquist

6

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author name string

Ross B Fulton

1

1 reference

4 August 2017

Sara E Hamilton

2

1 reference

4 August 2017

Yan Xing

3

1 reference

4 August 2017

J Adam Best

4

1 reference

4 August 2017

Ananda W Goldrath

5

1 reference

4 August 2017

language of work or name

English

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publication date

24 November 2014

1 reference

4 August 2017

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4 August 2017

volume

16

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4 August 2017

issue

1

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4 August 2017

page(s)

107-117

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Intrinsic CD4+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self peptide and MHC.

4 August 2017

cites work

1 reference

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IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Environmental cues dictate the fate of individual CD8+ T cells responding to infection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection.

7 July 2018

1 reference

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Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Peripheral prepositioning and local CXCL9 chemokine-mediated guidance orchestrate rapid memory CD8+ T cell responses in the lymph node

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

T cell-positive selection uses self-ligand binding strength to optimize repertoire recognition of foreign antigens

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Transcriptional control of effector and memory CD8+ T cell differentiation

7 July 2018

1 reference

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The transcription factor T-bet is induced by multiple pathways and prevents an endogenous Th2 cell program during Th1 cell responses

7 July 2018

1 reference

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Chemokine guidance of central memory T cells is critical for antiviral recall responses in lymph nodes.

7 July 2018

1 reference

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Distinct CD4+ helper T cells involved in primary and secondary responses to infection.

7 July 2018

1 reference

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Normal T cell homeostasis: the conversion of naive cells into memory-phenotype cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse

7 July 2018

1 reference

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Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division

7 July 2018

1 reference

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Signaling thresholds govern heterogeneity in IL-7-receptor-mediated responses of naïve CD8(+) T cells

7 July 2018

1 reference

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Interleukin-2 Receptor Signaling: At the Interface between Tolerance and Immunity

7 July 2018

1 reference

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Generation of effector CD8+ T cells and their conversion to memory T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Self-specific CD8+ T cells maintain a semi-naive state following lymphopenia-induced proliferation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Inflammatory cytokines as a third signal for T cell activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Dendritic cells control T cell tonic signaling required for responsiveness to foreign antigen

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

T cell receptor-dependent regulation of lipid rafts controls naive CD8+ T cell homeostasis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Naive T cell homeostasis: from awareness of space to a sense of place

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Self-class I MHC molecules support survival of naive CD8 T cells, but depress their functional sensitivity through regulation of CD8 expression levels

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

A default pathway of memory CD8 T cell differentiation after dendritic cell immunization is deflected by encounter with inflammatory cytokines during antigen-driven proliferation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

The antigen-specific CD8+ T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Complete but curtailed T-cell response to very low-affinity antigen

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Inflaming the CD8+ T cell response.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Competition for self-peptide-MHC complexes and cytokines between naive and memory CD8+ T cells expressing the same or different T cell receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Positive and negative selection of T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

MIP-1alpha, MIP-1beta, RANTES, and ATAC/lymphotactin function together with IFN-gamma as type 1 cytokines

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Sensory adaptation in naive peripheral CD4 T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Dynamic tuning of T cell reactivity by self-peptide-major histocompatibility complex ligands

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Differential requirements for survival and proliferation of CD8 naïve or memory T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

T cell receptor antagonist peptides induce positive selection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

Expression and phosphorylation of the Listeria monocytogenes ActA protein in mammalian cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270846

A role for CD5 in TCR-mediated signal transduction and thymocyte selection

7 July 2018

1 reference

TCR signals mediated by Src family kinases are essential for the survival of naive T cells

21 January 2018

1 reference

A role for TCR affinity in regulating naive T cell homeostasis.

21 January 2018

1 reference

'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR.

21 January 2018

1 reference

Signaling through Itk promotes T helper 2 differentiation via negative regulation of T-bet

21 January 2018

1 reference

Selective expression of the chemokine receptor XCR1 on cross-presenting dendritic cells determines cooperation with CD8+ T cells.

21 January 2018

1 reference

Disparate individual fates compose robust CD8+ T cell immunity

21 January 2018

1 reference

Heterogeneous differentiation patterns of individual CD8+ T cells.

21 January 2018

1 reference

Recruitment of antigen-specific CD8+ T cells in response to infection is markedly efficient

21 January 2018

1 reference

Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination.

21 January 2018

1 reference

Peripheral "CD8 tuning" dynamically modulates the size and responsiveness of an antigen-specific T cell pool in vivo.

21 January 2018

1 reference

Antigen-Specific Modulation of an Immune Response by In Vivo Administration of Soluble MHC Class I Tetramers

21 January 2018

1 reference

Lower receptor avidity required for thymic clonal deletion than for effector T-cell function

21 January 2018

1 reference

CD4+ T cell survival is not directly linked to self-MHC-induced TCR signaling

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25419629

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Il-12 enhances CD8 T cell homeostatic expansion

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25419629

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Peripheral expression of self-MHC-II influences the reactivity and self-tolerance of mature CD4(+) T cells: evidence from a lymphopenic T cell model

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25419629

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NI.3043

1 reference

4 August 2017

1 reference

4 August 2017

1 reference