δ-Conotoxins synthesized using an acid-cleavable solubility tag approach reveal key structural determinants for NaV subtype selectivity. (Q34737924)

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22 February 2020

title

δ-Conotoxins synthesized using an acid-cleavable solubility tag approach reveal key structural determinants for NaV subtype selectivity (English)

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22 February 2020

5

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Jan Tytgat

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22 February 2020

author name string

Steve Peigneur

1

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22 February 2020

Marianne Paolini-Bertrand

2

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22 February 2020

Hubert Gaertner

3

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22 February 2020

Daniel Biass

4

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22 February 2020

Reto Stöcklin

6

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22 February 2020

Philippe Favreau

7

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22 February 2020

Oliver Hartley

9

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22 February 2020

language of work or name

English

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publication date

28 October 2014

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Journal of Biological Chemistry

22 February 2020

published in

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volume

289

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22 February 2020

issue

51

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22 February 2020

page(s)

35341-35350

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The insecticidal potential of venom peptides

22 February 2020

cites work

1 reference

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7 July 2018

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Molecular phylogeny, classification and evolution of conopeptides

7 July 2018

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Recent developments regarding voltage-gated sodium channel blockers for the treatment of inherited and acquired neuropathic pain syndromes

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Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders.

7 July 2018

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Comparative proteomic study of the venom of the piscivorous cone snail Conus consors

7 July 2018

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Requirements for prediction of peptide retention time in reversed-phase high-performance liquid chromatography: hydrophilicity/hydrophobicity of side-chains at the N- and C-termini of peptides are dramatically affected by the end-groups and location

7 July 2018

1 reference

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Molecular interaction of delta-conotoxins with voltage-gated sodium channels.

7 July 2018

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NMR solution structures of delta-conotoxin EVIA from Conus ermineus that selectively acts on vertebrate neuronal Na+ channels

7 July 2018

1 reference

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Nomenclature of voltage-gated sodium channels

7 July 2018

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7 July 2018

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Synthesis of proteins by native chemical ligation

21 January 2018

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A delta-conotoxin from Conus ermineus venom inhibits inactivation in vertebrate neuronal Na+ channels but not in skeletal and cardiac muscles.

7 July 2018

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A natural point mutation changes both target selectivity and mechanism of action of sea anemone toxins.

21 January 2018

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Delta-conotoxin structure/function through a cladistic analysis

21 January 2018

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The synthesis of 'difficult' peptides using 2-hydroxy-4-methoxybenzyl or pseudoproline amino acid building blocks: a comparative study.

21 January 2018

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Towards the total chemical synthesis of integral membrane proteins: a general method for the synthesis of hydrophobic peptide-thioester building blocks.

21 January 2018

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Use of a temporary "solubilizing" peptide tag for the Fmoc solid-phase synthesis of human insulin glargine via use of regioselective disulfide bond formation.

21 January 2018

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Purification, characterization, synthesis, and cloning of the lockjaw peptide from Conus purpurascens venom

21 January 2018

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12 December 2020

Effect of conformation on the conversion of cyclo-(1,7)-Gly-Arg-Gly-Asp-Ser-Pro-Asp-Gly-OH to its cyclic imide degradation product

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12 December 2020

Propeptide does not act as an intramolecular chaperone but facilitates protein disulfide isomerase-assisted folding of a conotoxin precursor

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12 December 2020

Delta-conotoxin GmVIA, a novel peptide from the venom of Conus gloriamaris

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12 December 2020

A new conotoxin affecting sodium current inactivation interacts with the delta-conotoxin receptor site

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12 December 2020

In situ neutralization in Boc-chemistry solid phase peptide synthesis. Rapid, high yield assembly of difficult sequences

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12 December 2020

Identifiers

DOI

10.1074/JBC.M114.610436

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22 February 2020

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22 February 2020

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