Long-chain ceramide is elevated in presenilin 1 (PS1M146V) mouse brain and induces apoptosis in PS1 astrocytes (Q34738174)

4 August 2017

title

Long-chain ceramide is elevated in presenilin 1 (PS1M146V) mouse brain and induces apoptosis in PS1 astrocytes (English)

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4 August 2017

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Guanghu Wang

1

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4 August 2017

Jeane Silva

series ordinal

2

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4 August 2017

Somsankar Dasgupta

series ordinal

3

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4 August 2017

Erhard Bieberich

series ordinal

4

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4 August 2017

publication date

1 March 2008

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4 August 2017

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4 August 2017

volume

56

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4 August 2017

issue

4

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4 August 2017

page(s)

449-456

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Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide

4 August 2017

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Selective apoptosis of pluripotent mouse and human stem cells by novel ceramide analogues prevents teratoma formation and enriches for neural precursors in ES cell-derived neural transplants

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Nerve Growth Factor-induced p75-mediated Death of Cultured Hippocampal Neurons Is Age-dependent and Transduced through Ceramide Generated by Neutral Sphingomyelinase

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Human homologues of LAG1 reconstitute Acyl-CoA-dependent ceramide synthesis in yeast

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Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease

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Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation

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AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4

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Fibrillar amyloid-beta peptides kill human primary neurons via NADPH oxidase-mediated activation of neutral sphingomyelinase. Implications for Alzheimer's disease

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Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: a shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease?

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Mechanisms of cell death in Alzheimer's disease: role of presenilins

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Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors

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7 January 2021

Astroglial expression of ceramide in Alzheimer's disease brains: a role during neuronal apoptosis.

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7 January 2021

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Direct binding to ceramide activates protein kinase Czeta before the formation of a pro-apoptotic complex with PAR-4 in differentiating stem cells

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7 January 2021

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7 January 2021

Aberrant induction of Par-4 is involved in apoptosis of hippocampal neurons in presenilin-1 M146V mutant knock-in mice

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7 January 2021

Apoptosis in the nervous system

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7 January 2021

Identifiers

DOI

10.1002/GLIA.20626

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4 August 2017

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