Targeting Hepatitis B Virus With CRISPR/Cas9. (Q34745348)

4 August 2017

title

Targeting Hepatitis B Virus With CRISPR/Cas9. (English)

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4 August 2017

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Christoph Seeger

1

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4 August 2017

Ji A Sohn

series ordinal

2

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4 August 2017

publication date

16 December 2014

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Molecular Therapy. Nucleic acids

4 August 2017

published in

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4 August 2017

volume

3

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4 August 2017

page(s)

e216

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Virology. Comment on "Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA".

4 August 2017

cites work

1 reference

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Development and applications of CRISPR-Cas9 for genome engineering

7 July 2018

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AAV-mediated delivery of zinc finger nucleases targeting hepatitis B virus inhibits active replication

7 July 2018

1 reference

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Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Genetic screens in human cells using the CRISPR-Cas9 system

7 July 2018

1 reference

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Genome engineering using the CRISPR-Cas9 system

7 July 2018

1 reference

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Duck hepatitis B virus covalently closed circular DNA appears to survive hepatocyte mitosis in the growing liver.

7 July 2018

1 reference

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Inactivation of hepatitis B virus replication in cultured cells and in vivo with engineered transcription activator-like effector nucleases.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

DNA targeting specificity of RNA-guided Cas9 nucleases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

7 July 2018

1 reference

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Sodium-dependent taurocholic cotransporting polypeptide: a candidate receptor for human hepatitis B virus

7 July 2018

1 reference

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Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

7 July 2018

1 reference

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Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

7 July 2018

1 reference

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Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Characterization of the host factors required for hepadnavirus covalently closed circular (ccc) DNA formation

7 July 2018

1 reference

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A rapid and general assay for monitoring endogenous gene modification

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Zinc-finger nucleases as a novel therapeutic strategy for targeting hepatitis B virus DNAs.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Mechanism for CCC DNA synthesis in hepadnaviruses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Dynamics of hepatitis B virus clearance in chimpanzees

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases in vitro and in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Hepatocyte turnover during resolution of a transient hepadnaviral infection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Conditional replication of duck hepatitis B virus in hepatoma cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Kinetics of hepadnavirus loss from the liver during inhibition of viral DNA synthesis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Hepatitis B virus biology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Apoptosis and regeneration of hepatocytes during recovery from transient hepadnavirus infections

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

A human mitochondrial DNA standard reference material for quality control in forensic identification, medical diagnosis, and mutation detection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Lack of effect of antiviral therapy in nondividing hepatocyte cultures on the closed circular DNA of woodchuck hepatitis virus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Inducible expression of human hepatitis B virus (HBV) in stably transfected hepatoblastoma cells: a novel system for screening potential inhibitors of HBV replication.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Covalently closed circular viral DNA formed from two types of linear DNA in woodchuck hepatitis virus-infected liver.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Construction of avian hepadnavirus variants with enhanced replication and cytopathicity in primary hepatocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Woodchuck hepatitis virus infections: very rapid recovery after a prolonged viremia and infection of virtually every hepatocyte

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Selective extraction of polyoma DNA from infected mouse cell cultures

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Biochemical and genetic evidence for the hepatitis B virus replication strategy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Mutations affecting hepadnavirus plus-strand DNA synthesis dissociate primer cleavage from translocation and reveal the origin of linear viral DNA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Hepatitis B virus X protein stimulates gene expression selectively from extrachromosomal DNA templates

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Formation of the pool of covalently closed circular viral DNA in hepadnavirus-infected cells

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272409

Hepatitis B virus infection

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25514649

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25514649

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Hepatitis B virus infection

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FMTNA.2014.68

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/MTNA.2014.68

1 reference

4 August 2017

1 reference

4 August 2017

1 reference