Protein misfolding, amyloid formation, and neurodegeneration: a critical role for molecular chaperones? (Q34747079)

4 August 2017

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title

Protein misfolding, amyloid formation, and neurodegeneration: a critical role for molecular chaperones? (English)

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4 August 2017

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Paul J Muchowski

1

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PubMed ID

12123602

4 August 2017

language of work or name

English

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publication date

1 July 2002

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4 August 2017

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4 August 2017

35

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4 August 2017

1

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4 August 2017

9-12

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Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

4 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Molecular chaperones enhance the degradation of expanded polyglutamine repeat androgen receptor in a cellular model of spinal and bulbar muscular atrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Small heat-shock proteins and their potential role in human disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Identification of genes that modify ataxin-1-induced neurodegeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Alpha-synuclein and neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Molecular chaperones in the cytosol: from nascent chain to folded protein

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Genetic suppression of polyglutamine toxicity in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Requirement of an intact microtubule cytoskeleton for aggregation and inclusion body formation by a mutant huntingtin fragment.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Amyloid fibrillogenesis: themes and variations

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

Glutamine repeats and neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900761-4

7 January 2021

10.1016/S0896-6273(02)00761-4

Identifiers

DOI

1 reference

4 August 2017

1 reference

PubMed ID

12123602