Alanine scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity. (Q34747442)

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2 January 2020

title

Alanine scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity (English)

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2 January 2020

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3

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2 January 2020

Conan K Wang

series ordinal

4

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2 January 2020

Norelle L Daly

series ordinal

6

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2 January 2020

David Craik

series ordinal

7

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2 January 2020

1

Shane M Simonsen

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2 January 2020

2

Lillian Sando

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2 January 2020

5

Michelle L Colgrave

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2 January 2020

language of work or name

English

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publication date

7 February 2008

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Journal of Biological Chemistry

2 January 2020

published in

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2 January 2020

volume

283

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2 January 2020

issue

15

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2 January 2020

page(s)

9805-9813

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Elucidation of the primary and three-dimensional structure of the uterotonic polypeptide kalata B1

2 January 2020

cites work

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Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif

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Cyclopsychotride A, a biologically active, 31-residue cyclic peptide isolated from Psychotria longipes

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First cyclotide from Hybanthus (Violaceae).

21 January 2018

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Tissue-specific expression of head-to-tail cyclized miniproteins in Violaceae and structure determination of the root cyclotide Viola hederacea root cyclotide1.

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A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae)

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Circular proteins--no end in sight

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Chemistry. Seamless proteins tie up their loose ends

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Oldenlandia affinis (R&S) DC

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A novel anti-HIV macrocyclic peptide from Palicourea condensata

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An unusual structural motif of antimicrobial peptides containing end-to-end macrocycle and cystine-knot disulfides

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Reversible antifouling effect of the cyclotide cycloviolacin O2 against barnacles

21 January 2018

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Biosynthesis and insecticidal properties of plant cyclotides: the cyclic knotted proteins from Oldenlandia affinis

21 January 2018

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Mechanism of action of cytotoxic cyclotides: cycloviolacin O2 disrupts lipid membranes.

21 January 2018

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A comparison of the self-association behavior of the plant cyclotides kalata B1 and kalata B2 via analytical ultracentrifugation.

21 January 2018

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Structural characterization of an unusually stable cyclic peptide, kalata B2 from Oldenlandia affinis.

21 January 2018

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Isolation, solution structure, and insecticidal activity of kalata B2, a circular protein with a twist: do Möbius strips exist in nature?

21 January 2018

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Thermal, chemical, and enzymatic stability of the cyclotide kalata B1: the importance of the cyclic cystine knot.

21 January 2018

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The cystine knot motif in toxins and implications for drug design.

21 January 2018

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Biosynthesis of the cyclotide Kalata B1 by using protein splicing

21 January 2018

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Twists, knots, and rings in proteins. Structural definition of the cyclotide framework

21 January 2018

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Synthesis of large cyclic cystine-knot peptide by orthogonal coupling strategy using unprotected peptide precursor

21 January 2018

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Torsion angle dynamics for NMR structure calculation with the new program DYANA

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New applications of simulated annealing in X-ray crystallography and solution NMR.

21 January 2018

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Torsion angle dynamics: reduced variable conformational sampling enhances crystallographic structure refinement

21 January 2018

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Torsion-angle molecular dynamics as a new efficient tool for NMR structure calculation.

21 January 2018

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Influence of non-bonded parameters on the quality of NMR structures: a new force field for NMR structure calculation

21 January 2018

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Chemical synthesis and folding pathways of large cyclic polypeptides: studies of the cystine knot polypeptide kalata B1.

21 January 2018

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Synthesis of proteins by native chemical ligation

21 January 2018

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Relationship between nuclear magnetic resonance chemical shift and protein secondary structure

21 January 2018

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Refined structure and metal binding site of the kalata B1 peptide

21 January 2018

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A biomimetic strategy in the synthesis and fragmentation of cyclic protein

21 January 2018

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21 January 2018

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Acyclic permutants of naturally occurring cyclic proteins. Characterization of cystine knot and beta-sheet formation in the macrocyclic polypeptide kalata B1.

21 January 2018

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Capped acyclic permutants of the circular protein kalata B1.

21 January 2018

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Key role of glutamic acid for the cytotoxic activity of the cyclotide cycloviolacin O2.

21 January 2018

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Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides

21 January 2018

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Cytolytic pore-forming proteins and peptides: is there a common structural motif?

21 January 2018

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Structure-activity relationships of alpha-conotoxins targeting neuronal nicotinic acetylcholine receptors

21 January 2018

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Conus peptides: novel probes for nicotinic acetylcholine receptor structure and function.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M709303200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18258598%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference