Using mouse models to dissect the genetics of obesity (Q34750310)

4 August 2017

1 reference

title

Using mouse models to dissect the genetics of obesity (English)

1 reference

4 August 2017

0 references

Gudrun A Brockmann

1

1 reference

PubMed ID

12127777

4 August 2017

Marianna R Bevova

series ordinal

2

1 reference

4 August 2017

1 July 2002

1 reference

4 August 2017

1 reference

4 August 2017

18

1 reference

4 August 2017

367-376

1 reference

4 August 2017

7

1 reference

Obesity as a medical problem

4 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Central nervous system control of food intake

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Towards a molecular understanding of adaptive thermogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

A genetic analysis of weight and overweight in 4-year-old twin pairs

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

A twin study of human obesity.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

The aetiology of obesity in children. A study of 101 twin pairs

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Recent advances in the genetics of severe childhood obesity

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Profound obesity associated with a balanced translocation that disrupts the SIM1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Congenital leptin deficiency is associated with severe early-onset obesity in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

A genome-wide scan for obesity in African-Americans

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

A Genome-Wide Scan for Abdominal Fat Assessed by Computed Tomography in the Quebec Family Study

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Segregation analysis of body mass index in a large sample selected for obesity: the Swedish Obese Subjects study

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Knockout models resulting in the development of obesity

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Capitalizing on large-scale mouse mutagenesis screens

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Rodent obesity models: an overview

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Cloning of the mouse agouti gene predicts a secreted protein ubiquitously expressed in mice carrying the lethal yellow mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Positional cloning of the mouse obese gene and its human homologue

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Identification and expression cloning of a leptin receptor, OB-R

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Identification and characterization of the mouse obesity gene tubby: a member of a novel gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

The mouse mahogany locus encodes a transmembrane form of human attractin

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Genome-wide, large-scale production of mutant mice by ENU mutagenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Quantitative trait loci for body weight in the intercross between SM/J and A/J mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Mapping quantitative trait loci for murine growth: a closer look at genetic architecture

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Mapping of obesity QTLs in a cross between mouse lines divergently selected on fat content

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Inherited non-autosomal effects on body fat in F2 mice derived from an AKR/J x SWR/J cross

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Dietary obesity linked to genetic loci on chromosomes 9 and 15 in a polygenic mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Genetics of dietary obesity in AKR/J x SWR/J mice: segregation of the trait and identification of a linked locus on chromosome 4

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Sensitivity to dietary obesity linked to a locus on chromosome 15 in a CAST/Ei x C57BL/6J F2 intercross

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Gender-influenced obesity QTLs identified in a cross involving the KK type II diabetes-prone mouse strain

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Genetic architecture of adiposity in the cross of LG/J and SM/J inbred mice

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Quantitative trait loci for growth traits in C57BL/6J x DBA/2J mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Single QTL effects, epistasis, and pleiotropy account for two-thirds of the phenotypic F(2) variance of growth and obesity in DU6i x DBA/2 mice

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Multiple obesity QTLs identified in an intercross between the NZO (New Zealand obese) and the SM (small) mouse strains

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Mapping quantitative trait loci for body weight on the X chromosome in mice. I. Analysis of a reciprocal F2 population

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Experimental strategies for the genetic dissection of complex traits in animal models

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Analysing complex genetic traits with chromosome substitution strains

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Gene-environment interaction: a significant diet-dependent obesity locus demonstrated in a congenic segment on mouse chromosome 7.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

High-resolution quantitative trait locus mapping for body weight in mice by recombinant progeny testing

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Distribution of body weight, blood insulin and lipid levels in the SMXA recombinant inbred strains and the QTL analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Synergistic gene interactions control the induction of the mitochondrial uncoupling protein (Ucp1) gene in white fat tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Fine mapping of trypanosomiasis resistance loci in murine advanced intercross lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Susceptibility to testicular germ-cell tumours in a 129.MOLF-Chr 19 chromosome substitution strain

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Quantitative trait loci in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Transgenic mice overexpressing gamma-aminobutyric acid transporter subtype I develop obesity

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

A transgenic model of visceral obesity and the metabolic syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Role of brain insulin receptor in control of body weight and reproduction.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Improved Glucose and Lipid Metabolism in Genetically Obese Mice Lacking aP2

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Absence of perilipin results in leanness and reverses obesity in Lepr(db/db) mice

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Disruption of the plasminogen activator inhibitor 1 gene reduces the adiposity and improves the metabolic profile of genetically obese and diabetic ob/ob mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Protection from obesity in mice lacking the VLDL receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Genetic dissection of obesity in polygenic animal models

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Mapping quantitative trait loci for body weight on the X chromosome in mice. II. Analysis of congenic backcrosses

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

Identification of four chromosomal loci determining obesity in a multifactorial mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2802%2902703-8

7 January 2021

10.1016/S0168-9525(02)02703-8

Identifiers

DOI

1 reference

4 August 2017

1 reference

PubMed ID

12127777