Large-scale chemical dissection of mitochondrial function (Q34754716)

4 August 2017

Large-scale chemical dissection of mitochondrial function (English)

1 reference

4 August 2017

7

Todd R Golub

1 reference

4 August 2017

6

Stuart L Schreiber

1 reference

4 August 2017

8

Vamsi K Mootha

1 reference

4 August 2017

Bridget K Wagner

1

1 reference

4 August 2017

Toshimori Kitami

2

1 reference

4 August 2017

Tamara J Gilbert

3

1 reference

4 August 2017

David Peck

4

1 reference

4 August 2017

Arvind Ramanathan

5

1 reference

4 August 2017

24 February 2008

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4 August 2017

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4 August 2017

26

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4 August 2017

3

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4 August 2017

343-351

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https://scigraph.springernature.com/pub.10.1038/nbt1387

4 August 2017

0 references

cites work

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Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators

7 July 2018

1 reference

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The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

7 July 2018

1 reference

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Statin-induced apoptosis and skeletal myopathy

7 July 2018

1 reference

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A method for high-throughput gene expression signature analysis

7 July 2018

1 reference

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Reactive oxygen species have a causal role in multiple forms of insulin resistance

7 July 2018

1 reference

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Oxidative stress-induced depolymerization of microtubules and alteration of mitochondrial mass in human cells

7 July 2018

1 reference

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PGC-1alpha regulates the mitochondrial antioxidant defense system in vascular endothelial cells

7 July 2018

1 reference

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Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements

7 July 2018

1 reference

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Mitochondria, oxidants, and aging

7 July 2018

1 reference

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Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs

7 July 2018

1 reference

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Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle

7 July 2018

1 reference

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Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus

7 July 2018

1 reference

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Calcium-regulated changes in mitochondrial phenotype in skeletal muscle cells

7 July 2018

1 reference

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Transcriptional regulatory circuits controlling mitochondrial biogenesis and function

7 July 2018

1 reference

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Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism

7 July 2018

1 reference

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Mitochondrial respiratory-chain diseases

7 July 2018

1 reference

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PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

7 July 2018

1 reference

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Mitochondrial dysfunction in the elderly: possible role in insulin resistance

7 July 2018

1 reference

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Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells

7 July 2018

1 reference

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Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes

7 July 2018

1 reference

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Control genes and variability: absence of ubiquitous reference transcripts in diverse mammalian expression studies

7 July 2018

1 reference

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Functional discovery via a compendium of expression profiles

7 July 2018

1 reference

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Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

7 July 2018

1 reference

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Interactions between bioenergetics and mitochondrial biogenesis

7 July 2018

1 reference

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An information-intensive approach to the molecular pharmacology of cancer.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715872

Molecular genetic aspects of human mitochondrial disorders

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715872

Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715872

Phase I and pharmacologic study of paclitaxel and cisplatin with granulocyte colony-stimulating factor: neuromuscular toxicity is dose-limiting

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715872

Myositis associated with griseofulvin therapy.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715872

Increased expression of mitochondrial-encoded genes in skeletal muscle of humans with diabetes mellitus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715872

Sequence and organization of the human mitochondrial genome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715872

Transcription of the mammalian mitochondrial genome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715872

Improvement of metabolic control in diabetic patients during mebendazole administration: preliminary studies.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715872

Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715872

Myotonia precipitated by propranolol therapy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715872

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715872

Respiratory enzymes in oxidative phosphorylation. III. The steady state.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715872

Rhabdomyolysis associated with pentamidine isethionate therapy for American cutaneous leishmaniasis

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715872

Metallothionein prevents diabetes-induced deficits in cardiomyocytes by inhibiting reactive oxygen species production

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715872

The use of ATP bioluminescence as a measure of cell proliferation and cytotoxicity

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715872

Synthesis and cellular profiling of diverse organosilicon small molecules

26 October 2018

1 reference

12 December 2020

Gene expression-based high-throughput screening(GE-HTS) and application to leukemia differentiation

1 reference

12 December 2020

Acute renal failure secondary to non-traumatic rhabdomyolysis following amoxapine overdose

1 reference

12 December 2020

Action of lovastatin, simvastatin, and pravastatin on sterol synthesis and their antiproliferative effect in cultured myoblasts from human striated muscle

1 reference

12 December 2020

Insulin-regulated mitochondrial gene expression is associated with glucose flux in human skeletal muscle

1 reference

12 December 2020

Coordinate induction of energy gene expression in tissues of mitochondrial disease patients

1 reference

12 December 2020

Relationship of stereochemical and skeletal diversity of small molecules to cellular measurement space

1 reference

12 December 2020

Identifiers

DOI

10.1038/NBT1387

1 reference

4 August 2017

1 reference

4 August 2017

1 reference