Cbl-transforming variants trigger a cascade of molecular alterations that lead to epithelial mesenchymal conversion (Q34764852)

4 August 2017

title

Cbl-transforming variants trigger a cascade of molecular alterations that lead to epithelial mesenchymal conversion (English)

1 reference

4 August 2017

T M Fournier

1

1 reference

4 August 2017

L Lamorte

2

1 reference

4 August 2017

C R Maroun

3

1 reference

4 August 2017

M Lupher

4

1 reference

4 August 2017

H Band

5

1 reference

4 August 2017

W Langdon

6

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4 August 2017

M Park

7

1 reference

4 August 2017

language of work or name

1 reference

1 October 2000

1 reference

Molecular Biology of the Cell

4 August 2017

published in

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4 August 2017

volume

11

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4 August 2017

issue

10

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4 August 2017

page(s)

3397-3410

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Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociation

4 August 2017

cites work

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Activation of nuclear factor of activated T cells-(NFAT) and activating protein 1 (AP-1) by oncogenic 70Z Cbl requires an intact phosphotyrosine binding domain but not Crk(L) or p85 phosphatidylinositol 3-kinase association

7 July 2018

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7 July 2018

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7 July 2018

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Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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The Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70.

7 July 2018

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Association of the Multisubstrate Docking Protein Gab1 with the Hepatocyte Growth Factor Receptor Requires a Functional Grb2 Binding Site Involving Tyrosine 1356

7 July 2018

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Efficient Cellular Transformation by the Met Oncoprotein Requires a Functional Grb2 Binding Site and Correlates with Phosphorylation of the Grb2-associated Proteins, Cbl and Gab1

7 July 2018

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Phosphotyrosine Binding Domain-Dependent Upregulation of the Platelet-Derived Growth Factor Receptor α Signaling Cascade by Transforming Mutants of Cbl: Implications for Cbl’s Function and Oncogenicity

7 July 2018

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7 July 2018

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7 July 2018

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Antisense repression of proto-oncogene c-Cbl enhances activation of the JAK-STAT pathway but not the ras pathway in epidermal growth factor receptor signaling

7 July 2018

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The proto-oncogene product p120(cbl) links c-Src and phosphatidylinositol 3'-kinase to the integrin signaling pathway.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

1 reference

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Receptor chimeras indicate that the met tyrosine kinase mediates the motility and morphogenic responses of hepatocyte growth/scatter factor.

7 July 2018

1 reference

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7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15002

sli-1, a negative regulator of let-23-mediated signaling in C. elegans

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15002

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15002

Hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells requires phosphatidylinositol 3-kinase.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15002

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15002

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7 July 2018

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Growth factors and cell movement

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15002

Alternative splicing generates isoforms of the met receptor tyrosine kinase which undergo differential processing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15002

DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15002

Regulation of beta 1-integrin-mediated cell adhesion by the Cbl adaptor protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15002

Efficient cell transformation by the Tpr-Met oncoprotein is dependent upon tyrosine 489 in the carboxy-terminus.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15002

The cell dissociation and motility triggered by scatter factor/hepatocyte growth factor are mediated through the cytoplasmic domain of the c-Met receptor

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15002

The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11029044

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11029044

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tyrosine 1356 in the carboxyl-terminal tail of the HGF/SF receptor is essential for the transduction of signals for cell motility and morphogenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11029044

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1091/MBC.11.10.3397

1 reference

4 August 2017

1 reference

4 August 2017

1 reference