Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis (Q34765872)

4 August 2017

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis (English)

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4 August 2017

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11

Michael Weller

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Heike Grassme

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Erich Gulbins

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Volker Teichgräber

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Martina Ulrich

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Nicole Endlich

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4 August 2017

Joachim Riethmüller

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Barbara Wilker

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4 August 2017

Cheyla Conceição De Oliveira-Munding

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4 August 2017

Anna M van Heeckeren

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Mark L Barr

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4 August 2017

Gabriele von Kürthy

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Kurt W Schmid

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Burkhard Tümmler

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Florian Lang

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Gerd Döring

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language of work or name

English

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publication date

30 March 2008

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4 August 2017

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14

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4 August 2017

382-391

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https://scigraph.springernature.com/pub.10.1038/nm1748

4 August 2017

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cites work

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Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

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Identification of the cystic fibrosis gene: genetic analysis

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Submucosal glands are the predominant site of CFTR expression in the human bronchus

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Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia

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Activation of NF-kappaB in airway epithelial cells is dependent on CFTR trafficking and Cl- channel function

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NF-kappaB activation and sustained IL-8 gene expression in primary cultures of cystic fibrosis airway epithelial cells stimulated with Pseudomonas aeruginosa.

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Early alterations in airway mucociliary clearance and inflammation of the lamina propria in CF mice

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Inflammation and infection in naive human cystic fibrosis airway grafts

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Mammalian ABC transporters in health and disease

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Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: modulation of cellular activity of sphingosine 1-phosphate

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7 January 2021

Defective acidification of intracellular organelles in cystic fibrosis

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7 January 2021

CFTR regulates phagosome acidification in macrophages and alters bactericidal activity

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7 January 2021

Signal transduction and the regulation of apoptosis: roles of ceramide

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7 January 2021

Raft ceramide in molecular medicine

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7 January 2021

Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

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7 January 2021

Host defense against Pseudomonas aeruginosa requires ceramide-rich membrane rafts

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7 January 2021

Purification and characterization of recombinant, human acid ceramidase. Catalytic reactions and interactions with acid sphingomyelinase

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7 January 2021

Isolation of cDNA clones encoding human acid sphingomyelinase: occurrence of alternatively processed transcripts

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7 January 2021

The ins and outs of sphingolipid synthesis

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7 January 2021

Sphingoid bases and de novo ceramide synthesis: enzymes involved, pharmacology and mechanisms of action

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7 January 2021

The tricyclic antidepressant desipramine causes proteolytic degradation of lysosomal sphingomyelinase in human fibroblasts

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7 January 2021

New insights on the use of desipramine as an inhibitor for acid ceramidase

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7 January 2021

Hypersusceptibility of cystic fibrosis mice to chronic Pseudomonas aeruginosa oropharyngeal colonization and lung infection

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7 January 2021

Role of mutant CFTR in hypersusceptibility of cystic fibrosis patients to lung infections.

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7 January 2021

Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death

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7 January 2021

Fenretinide corrects newly found ceramide deficiency in cystic fibrosis

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7 January 2021

Effects of synvinolin (MK-733) on plasma lipids in familial hypercholesterolaemia

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7 January 2021

Compartmentalization of ceramide signaling: physical foundations and biological effects

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7 January 2021

Loss of the chloride channel ClC-7 leads to lysosomal storage disease and neurodegeneration

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7 January 2021

ClC-3 chloride channels facilitate endosomal acidification and chloride accumulation

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7 January 2021

Evidence against defective trans-Golgi acidification in cystic fibrosis

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7 January 2021

Cystic fibrosis transmembrane conductance regulator-independent phagosomal acidification in macrophages

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7 January 2021

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7 January 2021

Gastrointestinal outcomes and confounders in cystic fibrosis

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7 January 2021

Impact of nutrition on phenotype in CFTR-deficient mice

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7 January 2021

A membrane lipid imbalance plays a role in the phenotypic expression of cystic fibrosis in cftr(-/-) mice

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7 January 2021

Effect of high fat diets with and without cholesterol on erythrocyte and tissue fatty acids in rats

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7 January 2021

Phosphatidylinositol (PI) and PI-associated arachidonate are elevated in platelet total membranes of type IIa hypercholesterolemic subjects

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7 January 2021

Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice

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7 January 2021

DNA fragmentation is a feature of cystic fibrosis epithelial cells: a disease with inappropriate apoptosis?

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7 January 2021

Pseudomonas aeruginosa-induced apoptosis is defective in respiratory epithelial cells expressing mutant cystic fibrosis transmembrane conductance regulator.

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7 January 2021

Extracellular DNA Required for Bacterial Biofilm Formation

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7 January 2021

Localization of cystic fibrosis transmembrane conductance regulator to lipid rafts of epithelial cells is required for Pseudomonas aeruginosa-induced cellular activation

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7 January 2021

A subpopulation of platelets responds to thrombin- or SFLLRN-stimulation with binding sites for factor IXa.

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7 January 2021

Chronic obstructive pulmonary disease - part 2: pathology and biochemistry of emphysema

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7 January 2021

Mucociliary flow in the trachea during anesthesia with enflurane, ether, nitrous oxide, and morphine

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7 January 2021

Identifiers

DOI

10.1038/NM1748

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Dimensions Publication ID

4 August 2017

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