Semen protects CD4+ target cells from HIV infection but promotes the preferential transmission of R5 tropic HIV (Q34767047)

4 August 2017

title

Semen protects CD4+ target cells from HIV infection but promotes the preferential transmission of R5 tropic HIV (English)

1 reference

4 August 2017

0 references

4

Wendy Wieland-Alter

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4 August 2017

5

Timothy Lahey

1 reference

4 August 2017

Emmanuel Balandya

1

1 reference

4 August 2017

Siddharth Sheth

series ordinal

2

1 reference

4 August 2017

Katherine Sanders

series ordinal

3

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4 August 2017

language of work or name

English

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publication date

8 November 2010

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4 August 2017

published in

Journal of Immunology

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4 August 2017

volume

185

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4 August 2017

issue

12

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4 August 2017

page(s)

7596-7604

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Increased levels of immune activation in the genital tract of healthy young women from sub-Saharan Africa

4 August 2017

cites work

1 reference

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7 July 2018

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High GUD incidence in the early 20 century created a particularly permissive time window for the origin and initial spread of epidemic HIV strains

7 July 2018

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7 July 2018

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7 July 2018

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Viruses within the Flaviviridae decrease CD4 expression and inhibit HIV replication in human CD4+ cells.

7 July 2018

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Spermatozoa capture HIV-1 through heparan sulfate and efficiently transmit the virus to dendritic cells

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Human uterine natural killer cells but not blood natural killer cells inhibit human immunodeficiency virus type 1 infection by secretion of CXCL12.

7 July 2018

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Mucin 6 in seminal plasma binds DC-SIGN and potently blocks dendritic cell mediated transfer of HIV-1 to CD4(+) T-lymphocytes

7 July 2018

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Persistence of HIV-1 receptor-positive cells after HSV-2 reactivation is a potential mechanism for increased HIV-1 acquisition

7 July 2018

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CD4 downregulation by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection

7 July 2018

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Cationic polypeptides contribute to the anti-HIV-1 activity of human seminal plasma.

7 July 2018

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7 July 2018

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Selective transmission of R5 HIV-1 over X4 HIV-1 at the dendritic cell-T cell infectious synapse is determined by the T cell activation state

7 July 2018

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Micro- and macrorheology of mucus

7 July 2018

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Seminal fluid drives expansion of the CD4+CD25+ T regulatory cell pool and induces tolerance to paternal alloantigens in mice

7 July 2018

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Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model

7 July 2018

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Measuring HIV neutralization in a luciferase reporter gene assay

7 July 2018

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Avoiding the void: cell-to-cell spread of human viruses

7 July 2018

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A new strategy to understand how HIV infects women: identification of a window of vulnerability during the menstrual cycle

7 July 2018

1 reference

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HIV-1 persists in breast milk cells despite antiretroviral treatment to prevent mother-to-child transmission

7 July 2018

1 reference

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Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

7 July 2018

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Setting the stage: host invasion by HIV.

7 July 2018

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Semen-derived amyloid fibrils drastically enhance HIV infection

7 July 2018

1 reference

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Human seminal plasma abrogates the capture and transmission of human immunodeficiency virus type 1 to CD4+ T cells mediated by DC-SIGN.

7 July 2018

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Amplified transmission of HIV-1: comparison of HIV-1 concentrations in semen and blood during acute and chronic infection

7 July 2018

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Initial events in establishing vaginal entry and infection by human immunodeficiency virus type-1.

7 July 2018

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Selective transmission of CCR5-utilizing HIV-1: the 'gatekeeper' problem resolved?

7 July 2018

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Seminal plasma and male factor signalling in the female reproductive tract.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Seminal plasma induces programmed cell death in cultured peripheral blood mononuclear cells.

7 July 2018

1 reference

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HIV preferentially infects HIV-specific CD4+ T cells

7 July 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071682

The role of semen in induction of maternal immune tolerance to pregnancy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071682

HIV-1 in semen: determination of proviral and viral titres compared to blood, and quantification of semen leukocyte populations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071682

Methods for the detection of male genital tract inflammation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071682

Genotypic and phenotypic characterization of HIV-1 patients with primary infection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071682

Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071682

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071682

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071682

Regulatory pathways governing HIV-1 replication

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071682

Selective transmission of human immunodeficiency virus type-1 variants from mothers to infants

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071682

Cell-to-cell spread of HIV-1 occurs within minutes and may not involve the participation of virus particles

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071682

Infection of macaques after vaginal exposure to cell-associated simian immunodeficiency virus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071682

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26 October 2018

1 reference

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1 reference

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26 October 2018

1 reference

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12 December 2020

Detection of HIV-1 RNA in seminal plasma samples from treated patients with undetectable HIV-1 RNA in blood plasma

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Quantitation of HIV-1-Specific IgG, IgA, and IgM Antibodies in Human Genital Tract Secretions

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Identifiers

DOI

10.4049/JIMMUNOL.1002846

1 reference

4 August 2017

1 reference

4 August 2017

1 reference