Myocilin and glaucoma: facts and ideas. (Q34768697)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150989%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

review article

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title

Myocilin and glaucoma: facts and ideas (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150989%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1

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11 November 2019

author name string

Ernst R Tamm

series ordinal

1

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4 August 2017

1 July 2002

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150989%20AND%20SRC:MED&resulttype=core&format=json

Progress in Retinal and Eye Research

11 November 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150989%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

volume

21

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11 November 2019

issue

4

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11 November 2019

page(s)

395-428

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150989%20AND%20SRC:MED&resulttype=core&format=json

Characterization of the murine TIGR/myocilin gene

11 November 2019

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Childhood-onset primary open angle glaucoma in a Canadian kindred: clinical and molecular genetic features

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Four structurally distinct neuron-specific olfactomedin-related glycoproteins produced by differential promoter utilization and alternative mRNA splicing from a single gene

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Characterization and comparison of the human and mouse GLC1A glaucoma genes

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Analysis of myocilin mutations in 1703 glaucoma patients from five different populations

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7 January 2021

Ultrastructural changes in the trabecular meshwork of juvenile glaucoma

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7 January 2021

The basic helix-loop-helix-zipper transcription factor USF1 regulates expression of the surfactant protein-A gene.

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Increased matrix metalloproteinases 1, 2, and 3 in the monkey uveoscleral outflow pathway after topical prostaglandin F(2 alpha)-isopropyl ester treatment

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ER stress response: getting the UPR hand on misfolded proteins

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Alpha-crystallin can function as a molecular chaperone

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The function of alpha-crystallin in vision

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7 January 2021

Expression of the TIGR gene in the iris, ciliary body, and trabecular meshwork of the human eye

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7 January 2021

Non-secretion of mutant proteins of the glaucoma gene myocilin in cultured trabecular meshwork cells and in aqueous humor

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7 January 2021

Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse

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7 January 2021

Clinical phenotype of juvenile-onset primary open-angle glaucoma linked to chromosome 1q.

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Ultrastructural changes in the trabecular meshwork of human eyes treated with corticosteroids

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7 January 2021

Evolution of olfactomedin. Structural constraints and conservation of primary sequence motifs

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Molecular evolution of olfactomedin

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TIGR gene in primary open-angle glaucoma and steroid-induced glaucoma

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A novel Asp380Ala mutation in the GLC1A/myocilin gene in a family with juvenile onset primary open angle glaucoma.

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7 January 2021

Targeted Disruption of the Myocilin Gene (Myoc) Suggests that Human Glaucoma-Causing Mutations Are Gain of Function

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Regulation of human myocilin/TIGR gene transcription in trabecular meshwork cells and astrocytes: role of upstream stimulatory factor

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7 January 2021

Morphological study of the anterior segment of cynomolgus monkey eyes following treatment with prostaglandin F2 alpha

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Upstream stimulatory factor 1 regulates osteopontin expression in smooth muscle cells

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7 January 2021

Novel mutations in the TIGR gene in early and late onset open angle glaucoma

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7 January 2021

A GLC1A gene Gln368Stop mutation in a patient with normal-tension open-angle glaucoma.

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7 January 2021

Juvenile open angle glaucoma: fine mapping of the TIGR gene to 1q24.3-q25.2 and mutation analysis

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7 January 2021

Transient loss of alphaB-crystallin: an early cellular response to mechanical stretch

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7 January 2021

Homozygotes carrying an autosomal dominant TIGR mutation do not manifest glaucoma

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7 January 2021

A rat model of chronic pressure-induced optic nerve damage

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7 January 2021

Differentially expressed olfactomedin-related glycoproteins (Pancortins) in the brain.

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The basic helix-loop-helix protein upstream stimulating factor regulates the cardiac ventricular myosin light-chain 2 gene via independent cis regulatory elements

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7 January 2021

Gene structure and properties of TIGR, an olfactomedin-related glycoprotein cloned from glucocorticoid-induced trabecular meshwork cells

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7 January 2021

Myocilin expression in the astrocytes of the optic nerve head

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7 January 2021

Immunofluorescence method for quantifying the trabecular meshwork glucocorticoid response (TIGR) protein in trabecular meshwork and Schlemm's canal cells

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7 January 2021

Identification of a contractile-responsive element in the cardiac alpha-myosin heavy chain gene

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7 January 2021

Cloning and characterization of subtracted cDNAs from a human ciliary body library encoding TIGR, a protein involved in juvenile open angle glaucoma with homology to myosin and olfactomedin.

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7 January 2021

Novel TIGR sequence alteration Val53Ala

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Transforming growth factor beta 2 levels in the aqueous humor in different types of glaucoma and the relation to filtering bleb development

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Cellular pharmacology and molecular biology of the trabecular meshwork inducible glucocorticoid response gene product

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Regulation of TIGR/MYOC gene expression in human trabecular meshwork cells

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TIGR/myocilin in human aqueous humor

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7 January 2021

Expression of myocilin/TIGR in normal and glaucomatous primate optic nerves

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7 January 2021

Transforming growth factor beta 1-responsive element: closely associated binding sites for USF and CCAAT-binding transcription factor-nuclear factor I in the type 1 plasminogen activator inhibitor gene

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7 January 2021

Binding of upstream stimulatory factor to an E-box in the 3'-flanking region stimulates alpha1(I) collagen gene transcription.

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7 January 2021

Why is intraocular pressure elevated in chronic simple glaucoma? Anatomical considerations

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7 January 2021

Electron microscopic studies on the trabecular meshwork in two cases of corticosteroid-glaucoma

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7 January 2021

Topical prostaglandin F2alpha treatment reduces collagen types I, III, and IV in the monkey uveoscleral outflow pathway

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7 January 2021

Transcriptional regulation of the mouse alpha A-crystallin gene: binding of USF to the -7/+5 region

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7 January 2021

Genetic linkage of familial open angle glaucoma to chromosome 1q21–q31

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7 January 2021

Age-dependent prevalence of mutations at the GLC1A locus in primary open-angle glaucoma

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7 January 2021

Ubiquitous expression of the 43- and 44-kDa forms of transcription factor USF in mammalian cells

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The mouse anterior chamber angle and trabecular meshwork develop without cell death

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7 January 2021

Olfactomedin: purification, characterization, and localization of a novel olfactory glycoprotein

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Identification of a new 'TIGR' mutation in a family with juvenile-onset primary open angle glaucoma.

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7 January 2021

Novel TIGR/MYOC mutations in families with juvenile onset primary open angle glaucoma

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7 January 2021

Identification of a gene that causes primary open angle glaucoma.

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7 January 2021

Mutations in the TIGR gene in familial primary open-angle glaucoma in Japan

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7 January 2021

Promoter mutations of myocilin gene in Japanese patients with open angle glaucoma including normal tension glaucoma

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7 January 2021

Expression pattern and in situ localization of the mouse homologue of the human MYOC (GLC1A) gene in adult brain.

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7 January 2021

Molecular cloning and expression profile of rat myocilin

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7 January 2021

Mouse myocilin (Myoc) gene expression in ocular tissues

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7 January 2021

The TIGR/MYOC gene and glaucoma: opportunities for new understandings

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7 January 2021

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7 January 2021

Contractile cells in the human scleral spur

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7 January 2021

Clinical phenotype of a Japanese family with primary open angle glaucoma caused by a Pro370Leu mutation in the MYOC/TIGR gene.

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7 January 2021

Immunohistochemical localization of MYOC/TIGR protein in the trabecular tissue of normal and glaucomatous eyes.

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7 January 2021

Characterization of the mouse Myoc/Tigr gene.

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7 January 2021

Aqueous humor in glaucomatous eyes contains an increased level of TGF-beta 2

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7 January 2021

Ultrastructural localization of myocilin in human trabecular meshwork cells and tissues

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7 January 2021

Myocilin is associated with mitochondria in human trabecular meshwork cells

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7 January 2021

Clinical features of five pedigrees genetically linked to the juvenile glaucoma locus on chromosome 1q21-q31

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7 January 2021

Genetic linkage of autosomal dominant juvenile glaucoma to 1q21-q31 in three affected pedigrees

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7 January 2021

Molecular and clinical evaluation of a patient hemizygous for TIGR/MYOC.

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7 January 2021

Prevalence of mutations in TIGR/Myocilin in patients with adult and juvenile primary open-angle glaucoma

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7 January 2021

Regulation of cardiac alpha-myosin heavy chain gene transcription by a contractile-responsive E-box binding protein

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7 January 2021

Molecular cloning of olfactomedin, an extracellular matrix protein specific to olfactory neuroepithelium

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7 January 2021

Detection of a new TIGR gene mutation in a Japanese family with primary open angle glaucoma.

1 reference

https://api.crossref.org/works/10.1016%2FS1350-9462%2802%2900010-1

7 January 2021

Mutations of the TIGR/MYOC gene in primary open-angle glaucoma in Korea

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7 January 2021

A cellular assay distinguishes normal and mutant TIGR/myocilin protein

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7 January 2021

10.1016/S1350-9462(02)00010-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150989%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference