Methyl-CpG binding proteins and cancer: are MeCpGs more important than MBDs? (Q34770530)

4 August 2017

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title

Methyl-CpG binding proteins and cancer: are MeCpGs more important than MBDs? (English)

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4 August 2017

Brian Hendrich

2

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author name string

Egor Prokhortchouk

series ordinal

1

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4 August 2017

language of work or name

English

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publication date

1 August 2002

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4 August 2017

number of pages

6

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inferred from page(s)

published in

Oncogene

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4 August 2017

volume

21

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4 August 2017

issue

35

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4 August 2017

page(s)

5394-5399

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Clues to the pathogenesis of familial colorectal cancer

4 August 2017

cites work

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Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

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Most microsatellite unstable sporadic colorectal carcinomas carry MBD4 mutations

21 January 2018

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Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency.

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MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1

21 January 2018

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DNA methylation patterns and epigenetic memory

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Methylation-induced repression--belts, braces, and chromatin

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Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene

21 January 2018

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Reduced rates of gene loss, gene silencing, and gene mutation in Dnmt1-deficient embryonic stem cells.

21 January 2018

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Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

21 January 2018

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Cytosine methylation and the fate of CpG dinucleotides in vertebrate genomes.

21 January 2018

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Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

21 January 2018

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A component of the transcriptional repressor MeCP1 shares a motif with DNA methyltransferase and HRX proteins

21 January 2018

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The catenin p120(ctn) interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factor

21 January 2018

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Inactivation of p16 in human mammary epithelial cells by CpG island methylation

21 January 2018

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A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

21 January 2018

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Identification and characterization of a family of mammalian methyl-CpG binding proteins

21 January 2018

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21 January 2018

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The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

21 January 2018

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Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

21 January 2018

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Cancer epigenetics comes of age

21 January 2018

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Methylation, mutation and cancer

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Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

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A cell cycle regulator potentially involved in genesis of many tumor types

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Reduced mRNA expression of the DNA demethylase, MBD2, in human colorectal and stomach cancers.

21 January 2018

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DNA methylation directs a time-dependent repression of transcription initiation

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Guidelines for reporting clinical features in cases with MECP2 mutations

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Hereditary predisposition to cancer.

21 January 2018

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Suppression of intestinal neoplasia by DNA hypomethylation.

21 January 2018

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Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA

21 January 2018

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DNA excision repair pathways

21 January 2018

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Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia

21 January 2018

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Loss of expression of HDAC-recruiting methyl-CpG-binding domain proteins in human cancer

21 January 2018

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MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

21 January 2018

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Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2

21 January 2018

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

21 January 2018

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DNA methylation specifies chromosomal localization of MeCP2.

21 January 2018

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Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase

21 January 2018

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21 January 2018

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7 January 2021

Active repression of methylated genes by the chromosomal protein MBD1

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Altered chromatin structure associated with methylation-induced gene silencing in cancer cells: correlation of accessibility, methylation, MeCP2 binding and acetylation

21 January 2018

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In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis

21 January 2018

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Investigation of the substrate spectrum of the human mismatch-specific DNA N-glycosylase MED1 (MBD4): fundamental role of the catalytic domain

21 January 2018

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The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor

21 January 2018

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The DNA repair gene MBD4 (MED1) is mutated in human carcinomas with microsatellite instability

21 January 2018

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The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.

21 January 2018

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Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

21 January 2018

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The expected equilibrium of the CpG dinucleotide in vertebrate genomes under a mutation model

21 January 2018

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Microsatellite instability in cancer of the proximal colon

21 January 2018

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Nuclear localization of the p120(ctn) Armadillo-like catenin is counteracted by a nuclear export signal and by E-cadherin expression

21 January 2018

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Methyl CpG binding proteins: coupling chromatin architecture to gene regulation

21 January 2018

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In vitro correction of G.T mispairs to G.C pairs in nuclear extracts from human cells

21 January 2018

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Mutagenic deamination of cytosine residues in DNA

21 January 2018

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Mammalian methyltransferases and methyl-CpG-binding domains: proteins involved in DNA methylation

21 January 2018

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7 January 2021

Rett's syndrome in the west of Scotland

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7 January 2021

Expression of mRNA for DNA methyltransferases and methyl-CpG-binding proteins and DNA methylation status on CpG islands and pericentromeric satellite regions during human hepatocarcinogenesis

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205631

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Dimensions Publication ID

4 August 2017

1045799913

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1 reference